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3-bromo-5-methylbenzoic acid

3-bromo-5-methylbenzoic acid Structure
3-bromo-5-methylbenzoic acid structure
CAS No.
58530-13-5
Chemical Name:
3-bromo-5-methylbenzoic acid
Synonyms
5-broMo-3-Methylbenzoic acid;3-bromo-5-methylbenzoic acid;Benzoic acid, 3-bromo-5-methyl-
CBNumber:
CB61558780
Molecular Formula:
C8H7BrO2
Molecular Weight:
215.04
MDL Number:
MFCD02684926
MOL File:
58530-13-5.mol
MSDS File:
SDS
Last updated:2026-05-28 03:52:07
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3-bromo-5-methylbenzoic acid Properties

Melting point 178-179.5℃
Boiling point 320.3±30.0 °C(Predicted)
Density 1.599±0.06 g/cm3 (20 ºC 760 Torr)
storage temp. Sealed in dry,Room Temperature
form solid
pka 3.88±0.10(Predicted)
color Pale yellow
InChI InChI=1S/C8H7BrO2/c1-5-2-6(8(10)11)4-7(9)3-5/h2-4H,1H3,(H,10,11)
InChIKey NWOMVQDBDBUANF-UHFFFAOYSA-N
SMILES C(O)(=O)C1=CC(C)=CC(Br)=C1

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P305+P351+P338
HS Code  2916310090

3-bromo-5-methylbenzoic acid price More Price(65)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich S17907 3-BROMO-5-METHYLBENZOIC ACID AldrichCPR 58530-13-5 1 unit $197 2026-04-30 Buy
Sigma-Aldrich S17907 3-BROMO-5-METHYLBENZOIC ACID Aldrich 58530-13-5 100mg $179 2024-03-01 Buy
Usbiological 424501 3-Bromo-5-methylbenzoic Acid 58530-13-5 100mg $319 2026-06-03 Buy
Usbiological 424501 3-Bromo-5-methylbenzoic Acid 58530-13-5 500mg $425 2026-06-03 Buy
Apolloscientific OR400183 3-Bromo-5-methylbenzoic acid >98% 58530-13-5 5g $21 2026-06-04 Buy
Product number Packaging Price Buy
S17907 1 unit $197 Buy
S17907 100mg $179 Buy
424501 100mg $319 Buy
424501 500mg $425 Buy
OR400183 5g $21 Buy

3-bromo-5-methylbenzoic acid Chemical Properties, Uses, Production

Chemical Properties

Off-white powder

Uses

3-Bromo-5-methylbenzoic Acid is an intermediate used to synthesize quinoline amide derivatives as novel VEGFR-2 inhibitors

Synthesis

1-bromo-3,5-dimethylbenzene (15 g, 81 mmol, 1.0 eq) in a mixture of pyridine (133 mL) and H2O (83 mL) was heated to 80°C. KMnO4 (25.6 g, 162 mmol, 2.0 eq) was added in portions over 45 min. After the addition was completed, heating was continued at 80°C for 1.5 h. The hot solution was then filtered, and the filtrate was acidified by addition of concentrated hydrochloric acid. The aqueous solution was extracted with EtOAc and the combined organic extracts washed with water and brine, dried (Na2SO4), filtered and evaporated in vacuo. The residue was purified by column chromatography (CH2Cl2 : MeOH, 80:1 to 40:1) to give 3-bromo-5-methylbenzoic acid. White solid, yield (5.2 g, 29 %). LC-MS: m/z 212.9, 215 [M+H]+. 1H NMR (400 MHz, MeOD) δ 7.91 (s, 1H), 7.79 (s, 1H), 7.57 (s, 1H), 2.38 (s, 3H).
synthesis of 3-bromo-5-methylbenzoic acid

References

[1] Patent: US2009/203657, 2009, A1. Location in patent: Page/Page column 53
[2] Patent: US2009/203677, 2009, A1. Location in patent: Page/Page column 56
[3] Patent: US2009/197871, 2009, A1. Location in patent: Page/Page column 55-56
[4] Patent: WO2009/100169, 2009, A1. Location in patent: Page/Page column 136

3-bromo-5-methylbenzoic acid synthesis

648439-19-4
58530-13-5
Synthesis of 3-bromo-5-methylbenzoic acid from (3-broMo-5-Methylphenyl)Methanol

3-bromo-5-methylbenzoic acid Preparation Products And Raw materials

Raw materials

7-Bromo-5-methyl-1H-indole-2,3-dione (3-broMo-5-Methylphenyl)Methanol 2-Amino-3-bromo-5-methylbenzoic acid 1-BroMo-3-broMoMethyl-5-Methyl-benzene 3-Bromo-5-methylbenzonitrile
2-Amino-5-methylbenzoic acid 5-Bromo-m-xylene Potassium permanganate Water Nitric acid

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Preparation Products

3-(aminomethyl)-5-bromobenzonitrile 3-Bromo-5-cyanobenzyl bromide

3-bromo-5-methylbenzoic acid Suppliers

Global Suppliers ( 137)
Supplier Tel Email Country ProdList Advantage
Shanghai ACT chemical Limited 021-59904146 18001826933 sales@actchemical.com China 476 56
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
Energy Chemical 400-0056266 sales8178@energy-chemical.com China 44850 61
Shijiazhuang Sdyano Fine Chemical Co., Ltd. 0311-89250318 13582355795 master@sjzsdyn.com China 2776 65
Wuhan Chemwish Technology Co., Ltd 86-027-67849912 sales@chemwish.com China 35884 56
Beijing Ouhe Technology Co., Ltd 13552068683 13522913783 2355560935@qq.com China 11777 60
Jia Xing Isenchem Co.,Ltd 0573-85285100 18627885956 isenchem@163.com China 9389 66
Accela ChemBio Co.,Ltd. 021-50795510 4000665055 marketing@accelachem.com China 10972 64
Shanghai Harvest Chemical Industrial Co., Ltd. 15721252604 17321035817 sales@harvest-chem.com China 2829 64
Shanghai Hanhong Scientific Co.,Ltd. 021-54306202 13764082696 info@hanhongsci.com China 42917 64
Supplier Advantage
Shanghai ACT chemical Limited 56
J & K SCIENTIFIC LTD. 76
Energy Chemical 61
Shijiazhuang Sdyano Fine Chemical Co., Ltd. 65
Wuhan Chemwish Technology Co., Ltd 56
Beijing Ouhe Technology Co., Ltd 60
Jia Xing Isenchem Co.,Ltd 66
Accela ChemBio Co.,Ltd. 64
Shanghai Harvest Chemical Industrial Co., Ltd. 64
Shanghai Hanhong Scientific Co.,Ltd. 64

View Latest Price from 3-bromo-5-methylbenzoic acid manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
3-bromo-5-methylbenzoic acid pictures 2026-03-20 3-bromo-5-methylbenzoic acid
58530-13-5
 $10.00 1KG 99% 10 mt Hebei Chuanghai Biotechnology Co., Ltd
3-bromo-5-methylbenzoic acid pictures 2024-08-21 3-bromo-5-methylbenzoic acid
58530-13-5
 1KG 98% 1TON Changzhou Anxuan Chemical Co., Ltd
3-Bromo-5-methylbenzoic acid pictures 2024-04-22 3-Bromo-5-methylbenzoic acid
58530-13-5
 $30.00-100.00 1kg 99.93% 1000kg per week Ouhuang Engineering Materials (Hubei) Co., Ltd

3-bromo-5-methylbenzoic acid Spectrum

3-bromo-5-methylbenzoic acid(58530-13-5)1HNMR

58530-13-5 (3-bromo-5-methylbenzoic acid) Related Search:

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3-bromo-5-methylbenzoic acid 5-broMo-3-Methylbenzoic acid Benzoic acid, 3-bromo-5-methyl- 58530-13-5