4-Methoxy-indoline-2,3-dione
- CAS No.
- 108937-87-7
- Chemical Name:
- 4-Methoxy-indoline-2,3-dione
- Synonyms
- 4-Methoxyindole-2,3-dione;Isalexin;4-Methoxy-indoline-2,3-dione;4-Methoxy-1H-Indole-2,3-dione;1H-Indole-2,3-dione, 4-methoxy-;2,3-Dihydro-4-methoxy-1H-indole-2,3-dione
- CBNumber:
- CB62598505
- Molecular Formula:
- C9H7NO3
- Molecular Weight:
- 177.16
- MDL Number:
- MFCD10000746
- MOL File:
- 108937-87-7.mol
- MSDS File:
- SDS
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319 |
| Precautionary statements | P261-P305+P351+P338 |
4-Methoxy-indoline-2,3-dione price More Price(32)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| AstaTech | 50156 | 4-METHOXYINDOLINE-2,3-DIONE 95% | 108937-87-7 | 0.1G | $77 | 2026-04-30 | Buy |
| AstaTech | 50156 | 4-METHOXYINDOLINE-2,3-DIONE 95% | 108937-87-7 | 0.25G | $123 | 2026-04-30 | Buy |
| AstaTech | 50156 | 4-METHOXYINDOLINE-2,3-DIONE 95% | 108937-87-7 | 1G | $357 | 2026-04-30 | Buy |
| aablocks | AA0082V7 | 4-Methoxyindoline-2,3-dione 95% | 108937-87-7 | 100mg | $111 | 2026-05-28 | Buy |
| aablocks | AA0082V7 | 4-Methoxyindoline-2,3-dione 95% | 108937-87-7 | 250mg | $162 | 2026-05-28 | Buy |
4-Methoxy-indoline-2,3-dione Chemical Properties, Uses, Production
Synthesis Reference(s)
Tetrahedron Letters, 35, p. 7303, 1994 DOI: 10.1016/0040-4039(94)85299-5
Synthesis
4837-90-5
108937-87-7
General procedure for the synthesis of 4-methoxyindoline-2,3-dione from 4-methoxyindole: 4-methoxyindole (18.25 mg, 0.17 mmol, 1.0 eq.) was dissolved in 1,2-dichloroethane (DCE) (2 mL), which was subsequently added to a solution containing pyridinium chlorochromate (PCC) (273 mg, 1.36 mmol, 8.0 equivalents) in a DCE solution (2 mL) and aluminum chloride (7 mg, 0.05 mmol, 0.3 equivalents) was added. The reaction mixture was heated at 80 °C for 2 h and then concentrated to dryness. The residue was purified by fast column chromatography (FCC) (eluent: ethyl acetate-hexane, 1:1) to afford 4-methoxyindoline-2,3-dione (16 mg, 0.09 mmol, 53% yield) in yellow powder form. The spectral data of the obtained compound were in agreement with literature reports.
References
[1] RSC Advances, 2015, vol. 5, # 46, p. 37018 - 37022
[2] Bioorganic and Medicinal Chemistry, 2017, vol. 25, # 2, p. 1 - 22
4-Methoxy-indoline-2,3-dione Preparation Products And Raw materials
4-Methoxy-indoline-2,3-dione Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| AstaTech (Chengdu) Pharma. Co., Ltd. | 15928766785 15928766785 | wupengcheng@astatech.cn | China | 1995 | 55 |
| Shanghai Tombiopharma Chemical Co. Ltd. | 13391076197 | tombiopharma@163.com | China | 4986 | 55 |
| SanoChem (Chengdu) Tech. Co., Ltd. | 28-87999436 02887999436 | sales@sano-chem.com | China | 3792 | 55 |
| ShangHai Angti Biotechnology Co., Ltd. | 13764913901 | info@angtibio.com | China | 4975 | 55 |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131885 | 58 |
| Hangzhou Molcore Biopharmatech Co.,Ltd | 400-711-5280 86-571-81025280 | sales@molcore.com | China | 9957 | 58 |
| Aikon International Limited | 025-58859352 15955137747 | sales01@aikonchem.com | China | 16021 | 58 |
| SuZhou Medinoah Co.,LTD. | 0512-69561983 13914027025 | zhang_q@medinoah.com | China | 3925 | 58 |
| Cool Pharm, Ltd | 021-58581007 18019463053 | sales@coolpharm.com | China | 9999 | 58 |
| Fan De(Beijing) Biotechnology Co., Ltd. | 15911056312 | liming@bio-fount.com | China | 9718 | 58 |
