7-Fluoroisatin
- CAS No.
- 317-20-4
- Chemical Name:
- 7-Fluoroisatin
- Synonyms
- 7-FLUOROINDOLINE-2,3-DIONE;1H-Indole-2,3-dione, 7-fluoro-;7-Flouroisatin;7-FL;7-FLUOROISATIN;7-Fluoroisation;7-FLUOROISATINE;7- fluorineisatin;BUTTPARK 24\07-37;7-Fluoroisatin>
- CBNumber:
- CB0181767
- Molecular Formula:
- C8H4FNO2
- Molecular Weight:
- 165.12
- MDL Number:
- MFCD01569508
- MOL File:
- 317-20-4.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Melting point | 192-196°C |
|---|---|
| Density | 1.477±0.06 g/cm3(Predicted) |
| storage temp. | Store at room temperature |
| pka | 8.44±0.20(Predicted) |
| form | powder to crystal |
| color | Light yellow to Brown |
| Water Solubility | Sparingly Soluble in water (0.022 g/L) |
| InChI | InChI=1S/C8H4FNO2/c9-5-3-1-2-4-6(5)10-8(12)7(4)11/h1-3H,(H,10,11,12) |
| InChIKey | HGBGVEOXPHGSOS-UHFFFAOYSA-N |
| SMILES | N1C2=C(C=CC=C2F)C(=O)C1=O |
| CAS DataBase Reference | 317-20-4(CAS DataBase Reference) |
| UNSPSC Code | 12352100 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302-H317 | |||||||||
| Precautionary statements | P280-P301+P312+P330-P302+P352 | |||||||||
| PPE | dust mask type N95 (US), Eyeshields, Faceshields, Gloves | |||||||||
| Hazard Codes | Xn,Xi | |||||||||
| Risk Statements | 22-43 | |||||||||
| Safety Statements | 37/39 | |||||||||
| WGK Germany | 3 | |||||||||
| HazardClass | IRRITANT | |||||||||
| HS Code | 29337900 | |||||||||
| Storage Class | 11 - Combustible Solids | |||||||||
| Hazard Classifications | Acute Tox. 4 Oral Skin Sens. 1 |
|||||||||
| NFPA 704 |
|
7-Fluoroisatin price More Price(60)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 679119 | 7-Fluoroisatin 96% | 317-20-4 | 5g | $155 | 2026-04-30 | Buy |
| TCI Chemical | F0551 | 7-Fluoroisatin >98.0%(GC)(T) | 317-20-4 | 5g | $85 | 2026-04-30 | Buy |
| TCI Chemical | F0551 | 7-Fluoroisatin >98.0%(GC)(T) | 317-20-4 | 25g | $309 | 2026-04-30 | Buy |
| Usbiological | 276802 | 7-Fluoroisatin Asreported | 317-20-4 | 10g | $369 | 2026-06-03 | Buy |
| Usbiological | 276802 | 7-Fluoroisatin Asreported | 317-20-4 | 25g | $512 | 2026-06-03 | Buy |
7-Fluoroisatin Chemical Properties, Uses, Production
Chemical Properties
White solid
Uses
7-Fluoroisatin is used as the intermediate of cardiovascular, anti-inflammatory and bactericidal drugs.
Synthesis Reference(s)
Organic Syntheses, Coll. Vol. 10, p. 23, 2004
Tetrahedron Letters, 35, p. 7303, 1994 DOI: 10.1016/0040-4039(94)85299-5
Synthesis
349-24-6
317-20-4
Step 2: 7-fluoroindoline-2,3-dione N-(2-fluorophenyl)-2-(hydroxyimino)acetamide (30 g, 164.84 mmol) was dissolved in concentrated sulfuric acid (100 mL), and the reaction was stirred at 80 °C for 2 hours. Upon completion of the reaction, the mixture was slowly poured into an ice-water mixture, and the precipitated brick-red solid was collected by filtration and dried to give 25 g of 7-fluorodihydroindole-2,3-dione in 90% yield. The product was analyzed by LCMS to confirm that the molecular ion peak was 166 (M + H)+.
References
[1] Patent: US2008/139558, 2008, A1. Location in patent: Page/Page column 55
[2] Journal of Heterocyclic Chemistry, 1990, vol. 27, # 7, p. 2151 - 2163
[3] Proceedings of the Royal Society of London, Series B: Biological Sciences, 1958, vol. 148, p. 481,488
[4] Journal of Medicinal Chemistry, 1992, vol. 35, # 11, p. 2085 - 2094
[5] European Journal of Medicinal Chemistry, 1994, vol. 29, # 10, p. 743 - 751
7-Fluoroisatin Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Weifang Yuda Pharmaceutical Technology Co., Ltd. | 17663603912 | 2710256076@qq.com | China | 119 | 56 |
| Carbott PharmTech Inc. | 0535-6385396 | info@carbottpharm.com | China | 996 | 56 |
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Meryer (Shanghai) Chemical Technology Co., Ltd. | 4006356688 18621169109 | market03@meryer.com | China | 40202 | 62 |
| INTATRADE GmbH | +49 3493/605464 | sales@intatrade.de | Germany | 3563 | 66 |
| Alfa Aesar | 400-6106006 | saleschina@alfa-asia.com | China | 30103 | 84 |
| TCI (Shanghai) Development Co., Ltd. | 021-67121386 | Sales-CN@TCIchemicals.com | China | 24512 | 81 |
| Beijing HwrkChemical Technology Co., Ltd | 89508211 18501085097 | sales.bj@hwrkchemical.com | China | 9407 | 55 |
| Energy Chemical | 400-0056266 | sales8178@energy-chemical.com | China | 44850 | 61 |
| Wuhan Chemwish Technology Co., Ltd | 86-027-67849912 | sales@chemwish.com | China | 35884 | 56 |
View Latest Price from 7-Fluoroisatin manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-09-02 | 7-Fluoroisatin
317-20-4
|
$1.50-36.00 | 1kg | 99% | Henan Fengda Chemical Co., Ltd | ||
 |
2026-05-18 | 7-Fluoroisatin
317-20-4
|
1kg | 98% | Hefei Lbao Physical & Chemical Science Co.,Ltd | |||
 |
2026-03-20 | 7-Fluoroisatin
317-20-4
|
$1.00 | 1KG | 99% | 10 mt | Hebei Chuanghai Biotechnology Co., Ltd |
-
- 7-Fluoroisatin
317-20-4
- $1.50-36.00
- 99%
- Henan Fengda Chemical Co., Ltd
-
- 7-Fluoroisatin
317-20-4
- $0.00
- 98%
- Hefei Lbao Physical & Chemical Science Co.,Ltd
-
- 7-Fluoroisatin
317-20-4
- $1.00
- 99%
- Hebei Chuanghai Biotechnology Co., Ltd
