1-Hydroxy-2-naphthoic acid
- CAS No.
- 86-48-6
- Chemical Name:
- 1-Hydroxy-2-naphthoic acid
- Synonyms
- NSC 3717;Xinafoic acid.;RARECHEM AL BE 0359;2-Carboxy-1-naphthol;1-Hydroxy-2-naphthoi;LABOTEST-BB LT00452757;1-Hydroxy-2-phthoic acid;hydroxy-2-naphthoic acid;1-Hydroxy-2-naphthoicaci;1-hydroxy-β-naphthoic acid
- CBNumber:
- CB6317591
- Molecular Formula:
- C11H8O3
- Molecular Weight:
- 188.18
- MDL Number:
- MFCD00003960
- MOL File:
- 86-48-6.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Melting point | 195-200 °C (dec.) (lit.) |
|---|---|
| Boiling point | 283.17°C (rough estimate) |
| Density | 1.2100 (rough estimate) |
| refractive index | 1.6310 (estimate) |
| Flash point | 150 °C |
| storage temp. | Sealed in dry,Room Temperature |
| solubility | alcohol: freely soluble |
| form | Powder or Crystals |
| pka | 3.02±0.30(Predicted) |
| color | White to slightly pink to tan |
| Water Solubility | SOLUBLE IN HOT WATER |
| Merck | 14,4834 |
| BRN | 974438 |
| InChI | 1S/C11H8O3/c12-10-8-4-2-1-3-7(8)5-6-9(10)11(13)14/h1-6,12H,(H,13,14) |
| InChIKey | SJJCQDRGABAVBB-UHFFFAOYSA-N |
| SMILES | OC(=O)c1ccc2ccccc2c1O |
| LogP | 3.196 (est) |
| CAS DataBase Reference | 86-48-6(CAS DataBase Reference) |
| FDA UNII | U8LZ3R07L8 |
| EPA Substance Registry System | 1-Hydroxy-2-naphthoic acid (86-48-6) |
| UNSPSC Code | 12352100 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P264-P271-P280-P302+P352-P305+P351+P338 | |||||||||
| target organs | Respiratory system | |||||||||
| PPE | dust mask type N95 (US), Eyeshields, Gloves | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 36/37/38 | |||||||||
| Safety Statements | 26-36-37/39-37 | |||||||||
| WGK Germany | 3 | |||||||||
| TSCA | TSCA listed | |||||||||
| HS Code | 29182910 | |||||||||
| Storage Class | 11 - Combustible Solids | |||||||||
| Hazard Classifications | Eye Irrit. 2 Skin Irrit. 2 STOT SE 3 |
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| NFPA 704 |
|
1-Hydroxy-2-naphthoic acid price More Price(47)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 109630 | 1-Hydroxy-2-naphthoic acid ≥97.0% | 86-48-6 | 5g | $37.5 | 2026-04-30 | Buy |
| Sigma-Aldrich | 109630 | 1-Hydroxy-2-naphthoic acid ≥97.0% | 86-48-6 | 100g | $65.3 | 2026-04-30 | Buy |
| TCI Chemical | H0279 | 1-Hydroxy-2-naphthoic Acid >98.0%(HPLC)(T) | 86-48-6 | 25g | $32 | 2026-04-30 | Buy |
| TCI Chemical | H0279 | 1-Hydroxy-2-naphthoic Acid >98.0%(HPLC)(T) | 86-48-6 | 500g | $322 | 2026-04-30 | Buy |
| TRC | TRC-H950850-5G | 1-Hydroxy-2-naphthoic Acid | 86-48-6 | 5g | $78 | 2026-06-03 | Buy |
1-Hydroxy-2-naphthoic acid Chemical Properties, Uses, Production
Chemical Properties
beige to brown-grey powder. 1-Hydroxy-2-naphthoic acid [86-48-6], C11H8O3, Mr 188.17, mp 200℃, is only sparingly soluble in hot water but readily soluble in alkali and ethanol. It couples with diazo compounds in the 4-position and, with excess, in the 4,7-positions. It is sulfonated by oleum to give the 4-sulfonic and then the 4,7-disulfonic acids. Halogenation occurs in the 4-position, and nitrosation gives 2-nitroso-1-naphthol.
Uses
Metabolite from phenanthrene degradation. 1-Hydroxy-2-naphthoic acid is used as an intermediate for azo and triphenylmethane dyes and, more recently, for color-film dyes.
Uses
It is an important raw material and intermediate used in Organic Synthesis, Pharmaceuticals, Agrochemicals and Dyestuff.
Definition
ChEBI: 1-hydroxy-2-naphthoic acid is a naphthoic acid with the carboxy group at position 2 and carrying a hydroxy substituent at the 1-position. It is a xenobiotic metabolite produced by the biodegradation of phenanthrene by microorganisms. It has a role as a bacterial xenobiotic metabolite and a fungal xenobiotic metabolite. It is a naphthoic acid, a member of naphthols and a hydroxy monocarboxylic acid. It is functionally related to a 2-naphthoic acid. It is a conjugate acid of a 1-hydroxy-2-naphthoate.
Preparation
Treatment of the dried sodium salt of 1-naphthol with carbon dioxide at 135℃ under pressure gives an 80 % yield of product.
General Description
1-Hydroxy-2-naphthoic acid is produced by the transformation of phenanthrene by NCIB 9816 clones.
Purification Methods
Successively crystallise the acid from EtOH/water, diethyl ether and acetonitrile, with filtration through a column of charcoal and Celite. [Tong & Glesmann J Am Chem Soc 79 583 1957, Beilstein 10 H 331, 10 IV 1194.]
1-Hydroxy-2-naphthoic acid Preparation Products And Raw materials
Raw materials
1of2
Preparation Products
1of2
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shanghai Kangtuo Chemical Co., Ltd. | 021-69185552 13701777608 | kangtuochem@163.com | China | 4224 | 55 |
| Shandong Xuchen Chemical Technology | 15698059122 15698059122 | 15698059122@163.com | China | 1673 | 58 |
| Hangzhou Copiore Chemical Co., Ltd. | 17300981287 13757145729 | sales@copiore.com | China | 291 | 58 |
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Meryer (Shanghai) Chemical Technology Co., Ltd. | 4006356688 18621169109 | market03@meryer.com | China | 40202 | 62 |
| Alfa Aesar | 400-6106006 | saleschina@alfa-asia.com | China | 30103 | 84 |
| TCI (Shanghai) Development Co., Ltd. | 021-67121386 | Sales-CN@TCIchemicals.com | China | 24512 | 81 |
| Ark Pharm, Inc. | 847-367-3680 | sales@arkpharminc.com | United States | 1669 | 56 |
| Beijing dtftchem Technology Co., Ltd. | 010-60275820 13031183356 | elainezt@sina.com | China | 1386 | 62 |
| Beijing HwrkChemical Technology Co., Ltd | 89508211 18501085097 | sales.bj@hwrkchemical.com | China | 9407 | 55 |
View Latest Price from 1-Hydroxy-2-naphthoic acid manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-08-27 | 1-Hydroxy-2-naphthoic acid
86-48-6
|
$29.00 | 99.85% | 10g | TargetMol Chemicals Inc. | ||
 |
2026-03-20 | 1-Hydroxy-2-naphthoic acid
86-48-6
|
$10.00 | 1KG | 99% | 10 mt | Hebei Chuanghai Biotechnology Co., Ltd | |
 |
2025-12-24 | 1-Hydroxy-2-naphthoic acid
86-48-6
|
1KG | 99.0% | 10000KG | Shaanxi Dideu Medichem Co. Ltd |
-
- 1-Hydroxy-2-naphthoic acid
86-48-6
- $29.00
- 99.85%
- TargetMol Chemicals Inc.
-
- 1-Hydroxy-2-naphthoic acid
86-48-6
- $10.00
- 99%
- Hebei Chuanghai Biotechnology Co., Ltd
-
- 1-Hydroxy-2-naphthoic acid
86-48-6
- 99.0%
- Shaanxi Dideu Medichem Co. Ltd
