Diethyl fluoromalonate
- CAS No.
- 685-88-1
- Chemical Name:
- Diethyl fluoromalonate
- Synonyms
- DIETHYL 2-FLUOROMALONATE;Propanedio;FLUOROMALONIC ACID DIETHYL ESTER;1,2-Difluoromalonate;Ethyl fluoromalonate;DIETHYL FLUOROMALONATE;Diethyl fluoromalonnate;DiethylfluoroMalonate96%;DiethylFluoromalonate>Diethylfluoromalonate,97%
- CBNumber:
- CB6479224
- Molecular Formula:
- C7H11FO4
- Molecular Weight:
- 178.16
- MDL Number:
- MFCD00009139
- MOL File:
- 685-88-1.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Boiling point | 121-122 °C30 mm Hg(lit.) |
|---|---|
| Density | 1.129 g/mL at 25 °C(lit.) |
| refractive index |
n |
| Flash point | 144 °F |
| storage temp. | under inert gas (nitrogen or Argon) at 2-8°C |
| pka | 10.40±0.46(Predicted) |
| form | Liquid |
| Specific Gravity | 1.129 |
| color | Clear colorless to pale yellow |
| BRN | 1775686 |
| InChI | InChI=1S/C7H11FO4/c1-3-11-6(9)5(8)7(10)12-4-2/h5H,3-4H2,1-2H3 |
| InChIKey | GOWQBFVDZPZZFA-UHFFFAOYSA-N |
| SMILES | C(OCC)(=O)C(F)C(OCC)=O |
| CAS DataBase Reference | 685-88-1(CAS DataBase Reference) |
| EWG's Food Scores | 1 |
| FDA UNII | 9RG5PXU326 |
| NIST Chemistry Reference | Diethyl fluoromalonate(685-88-1) |
| UNSPSC Code | 12352100 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS05 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H314 | |||||||||
| Precautionary statements | P280-P303+P361+P353-P304+P340+P310-P305+P351+P338-P363-P405 | |||||||||
| PPE | Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter | |||||||||
| Hazard Codes | C,T | |||||||||
| Risk Statements | 34 | |||||||||
| Safety Statements | 26-36/37/39-45-25-27 | |||||||||
| RIDADR | UN 3265 8/PG 2 | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | OO1670000 | |||||||||
| F | 19 | |||||||||
| Hazard Note | Corrosive | |||||||||
| HazardClass | 8 | |||||||||
| PackingGroup | III | |||||||||
| HS Code | 29171900 | |||||||||
| Storage Class | 8A - Combustible corrosive hazardous materials | |||||||||
| Hazard Classifications | Skin Corr. 1B | |||||||||
| REACH Registrations | Inactive | |||||||||
| Limited Quantities | 1.0 L (0.3 gallons) (liquid) or 1 Kg (2.2 lbs) (solid) | |||||||||
| Excepted Quantities | Max Inner Pack (30g or 30ml) and Max Outer Pack (500g or 500ml) | |||||||||
| NFPA 704 |
|
Diethyl fluoromalonate price More Price(57)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 285587 | Diethyl fluoromalonate 97% | 685-88-1 | 1ml | $102 | 2026-04-30 | Buy |
| TCI Chemical | F0283 | Diethyl Fluoromalonate >95.0%(GC) | 685-88-1 | 1g | $27 | 2026-04-30 | Buy |
| TCI Chemical | F0283 | Diethyl Fluoromalonate >95.0%(GC) | 685-88-1 | 5g | $87 | 2026-04-30 | Buy |
| Usbiological | 271096 | Diethyl 2-fluoromalonate ≥97%(GC) | 685-88-1 | 5g | $425 | 2026-06-03 | Buy |
| Usbiological | 271096 | Diethyl 2-fluoromalonate ≥97%(GC) | 685-88-1 | 10g | $638 | 2026-06-03 | Buy |
Diethyl fluoromalonate Chemical Properties, Uses, Production
Chemical Properties
CLEAR COLOURLESS TO PALE YELLOW LIQUID
Uses
The kinetic parameters of diethyl fluoromalonate in hemolysates were used to study carboxylesterase activities in complex systems.
General Description
The reaction of diethyl fluoromalonate with electron-poor and electron-rich, sterically hindered and unhindered aryl bromides and chlorides were studied.
Synthesis
In a 250m1 round bottom flask, 5g of sodium carbonate, 10g of cobalt octacarbonyl, 72ml (57g, 1. 25mol) of ethanol and 53ml (61g, 0. 5mol) of ethyl chloroacetate were added, and CO2 was passed through the gas at a flow rate of 50m1/min for 6h, and the reaction was completed. To the system was added 5 m1 of concentrated sulfuric acid, shaken for 15 min, and then distilled under reduced pressure to collect the 80C/4 mmHg fraction. Add 60ml of water to the distillate, adjust the pH to 0.3 with concentrated sulfuric acid, vibrate, separate the organic layer, and then carry out decompression distillation to collect 80C/ 4mmHg fraction, obtaining diethyl malonate 66~69ml (69.6g ~ 72.8g), the yield was about 87% ~ 91%.
16.0g(0.1mol) diethyl malonate and 47.0g(0.12mol) HTIB were added to an aluminum container, and heated by irradiation for 3min in a 700W microwave oven, cooled, and 19.0g of MgCl was added, and heated by irradiation for 2min, cooled, and extracted with 50ml of CH,Cl2 for two times, dried with anhydrous magnesium sulfate, and evaporated to remove the CH2Cl2 to obtain Diethyl chloromalonate. Diethyl chloromalonate 15.7g, yield 81%.
Diethyl fluoromalonate Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Xuchang Fengfei New Materials Technology Co., Ltd | 19713077352; 19713077352 | 1038096457@qq.com | China | 2333 | 58 |
| Yangzhou modier Electronic Materials Co., Ltd | 13761402923 19975033992 | market@modeltemol.com | China | 7841 | 58 |
| Dongguan Walixi Chemical Co., Ltd | 0796-8612228 18664658771 | 1489577060@qq.com | China | 4844 | 58 |
| Nanjing shengyilai Chemical Co., Ltd | 19951936396 | 3158688292@qq.com | China | 4850 | 58 |
| Changzhou Fourman Chemical Co., Ltd. | 0519-89882557 13912311481 | fourmanchem@163.com | China | 69 | 60 |
| SHANG FLUORO | 021-65170832 15601903708 | qinba_1@163.com | China | 401 | 60 |
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Meryer (Shanghai) Chemical Technology Co., Ltd. | 4006356688 18621169109 | market03@meryer.com | China | 40202 | 62 |
| Alfa Aesar | 400-6106006 | saleschina@alfa-asia.com | China | 30103 | 84 |
| TCI (Shanghai) Development Co., Ltd. | 021-67121386 | Sales-CN@TCIchemicals.com | China | 24512 | 81 |
View Latest Price from Diethyl fluoromalonate manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-08-25 | Diethyl fluoromalonate
685-88-1
|
$2.00-5.00 | 1kg | 99% | 100kg | ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD | |
 |
2025-05-23 | Diethyl fluoromalonate
685-88-1
|
$10.00 | 1kg | 99% | 20 ton | Hebei Zhuanglai Chemical Trading Co Ltd | |
 |
2025-04-04 | Diethyl fluoromalonate
685-88-1
|
1kg | 98% | 1Ton | Henan Aochuang Chemical Co.,Ltd.
|
-
- Diethyl fluoromalonate
685-88-1
- $2.00-5.00
- 99%
- ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD
-
- Diethyl fluoromalonate
685-88-1
- $10.00
- 99%
- Hebei Zhuanglai Chemical Trading Co Ltd
-
- Diethyl fluoromalonate
685-88-1
- 98%
- Henan Aochuang Chemical Co.,Ltd.
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