Ethyl hydrogen malonate
- CAS No.
- 1071-46-1
- Chemical Name:
- Ethyl hydrogen malonate
- Synonyms
- MONOETHYL MALONATE;3-ethoxy-3-oxopropanoate;3-ethoxy-3-oxo-propanoic acid;Monoethyl malonic acid;3-ethoxy-3-oxapropanoic acid;en maL;BROP-001;hydrogen maL;Ethyl hydrogen malon;Malonic acid 1-ethyl
- CBNumber:
- CB6477583
- Molecular Formula:
- C5H8O4
- Molecular Weight:
- 132.11
- MDL Number:
- MFCD00020490
- MOL File:
- 1071-46-1.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Melting point | -13°C(lit.) |
|---|---|
| Boiling point | 106.5 °C/3 mmHg (lit.) |
| Density | 1.119 g/mL at 25 °C (lit.) |
| refractive index |
n |
| Flash point | >230 °F |
| storage temp. | Sealed in dry,Room Temperature |
| solubility | Chloroform (Sparingly) |
| pka | pK1:3.55 (25°C) |
| form | Liquid |
| color | Pale yellow |
| Water Solubility | Miscible with water, chloroform and other solvents. |
| BRN | 1758845 |
| InChI | InChI=1S/C5H8O4/c1-2-9-5(8)3-4(6)7/h2-3H2,1H3,(H,6,7) |
| InChIKey | HGINADPHJQTSKN-UHFFFAOYSA-N |
| SMILES | C(OCC)(=O)CC(O)=O |
| CAS DataBase Reference | 1071-46-1(CAS DataBase Reference) |
| UNSPSC Code | 12352100 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P264-P271-P280-P302+P352-P305+P351+P338 | |||||||||
| target organs | Respiratory system | |||||||||
| PPE | Eyeshields, Gloves, type ABEK (EN14387) respirator filter | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 36/37/38 | |||||||||
| Safety Statements | 26-36 | |||||||||
| WGK Germany | 3 | |||||||||
| HS Code | 29171900 | |||||||||
| Storage Class | 10 - Combustible liquids | |||||||||
| Hazard Classifications | Eye Irrit. 2 Skin Irrit. 2 STOT SE 3 |
|||||||||
| REACH Registrations | Active | |||||||||
| NFPA 704 |
|
Ethyl hydrogen malonate price More Price(45)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 445088 | mono-Ethyl malonate | 1071-46-1 | 5g | $63.8 | 2026-04-30 | Buy |
| TCI Chemical | M2700 | Monoethyl Malonate >98.0%(T) | 1071-46-1 | 5g | $35 | 2026-04-30 | Buy |
| TCI Chemical | M2700 | Monoethyl Malonate >98.0%(T) | 1071-46-1 | 25g | $105 | 2026-04-30 | Buy |
| Usbiological | 275525 | Ethyl hydrogen malonate Asreported | 1071-46-1 | 10g | $319 | 2026-06-03 | Buy |
| Usbiological | 275525 | Ethyl hydrogen malonate Asreported | 1071-46-1 | 25g | $442 | 2026-06-03 | Buy |
Ethyl hydrogen malonate Chemical Properties,Uses,Production
Chemical Properties
Yellow liquid
Uses
Ethyl Hydrogen Malonate has been shown to impair brain mitochondrial succinate and malate transport. It is also found in the extract of Hericum erinaceus mushroom which shows antitumor effects in tumo r-bearing mice.
Uses
Ethyl hydrogen malonate is used as a reactant for the preparation of tetramic acids through Dieckmann ring closure and organocatalytic decarboxylative Doebner-Knoevenagel reactions. It is involved in the acylation reactions and Knoevenagel condensation with aldehydes. It is also used in the preparation of gamma-lactones from olefins by intermolecular carbolactonization in presence of Mn(III) acetate as a catalyst.
Definition
ChEBI: Monoethyl malonic acid is a dicarboxylic acid.
Synthesis Reference(s)
Organic Syntheses, Coll. Vol. 4, p. 417, 1963
Tetrahedron Letters, 26, p. 1411, 1985 DOI: 10.1016/S0040-4039(00)99058-0
Ethyl hydrogen malonate Preparation Products And Raw materials
Raw materials
Preparation Products
1of4
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Tianjin Ji Ping Jia Chemical Co., Ltd. | 18622448868 | jpjchem@163.com | China | 489 | 62 |
| Heze Chuangfa Biotechnology Co., Ltd. | 15864743015 15864743015 | 1187939516@qq.com | China | 144 | 58 |
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Meryer (Shanghai) Chemical Technology Co., Ltd. | 4006356688 18621169109 | market03@meryer.com | China | 40202 | 62 |
| Alfa Aesar | 400-6106006 | saleschina@alfa-asia.com | China | 30103 | 84 |
| TCI (Shanghai) Development Co., Ltd. | 021-67121386 | Sales-CN@TCIchemicals.com | China | 24512 | 81 |
| ShangHai DEMO Chemical Co.,Ltd | 400-021-7337 2355568890 | sales@demochem.com | China | 2569 | 57 |
| Energy Chemical | 400-0056266 | sales8178@energy-chemical.com | China | 44850 | 61 |
| JinYan Chemicals(ShangHai) Co.,Ltd. | 13817811078 | sales@jingyan-chemical.com | China | 9963 | 60 |
| Jia Xing Isenchem Co.,Ltd | 0573-85285100 18627885956 | isenchem@163.com | China | 9389 | 66 |
View Lastest Price from Ethyl hydrogen malonate manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-08-16 | 3-Ethoxy-3-oxopropanoic acid
1071-46-1
|
$29.00 | 99.72% | 10g | TargetMol Chemicals Inc. | ||
 |
2025-12-24 | Ethyl hydrogen malonate
1071-46-1
|
1KG | 98.0% | 10 | Shaanxi Dideu Medichem Co. Ltd | ||
 |
2025-04-04 | Ethyl hydrogen malonate
1071-46-1
|
1kg | 98% | 1Ton | Henan Aochuang Chemical Co.,Ltd.
|
-
- 3-Ethoxy-3-oxopropanoic acid
1071-46-1
- $29.00
- 99.72%
- TargetMol Chemicals Inc.
-
- Ethyl hydrogen malonate
1071-46-1
- $0.10
- 98.0%
- Shaanxi Dideu Medichem Co. Ltd
-
- Ethyl hydrogen malonate
1071-46-1
- 98%
- Henan Aochuang Chemical Co.,Ltd.
