2,3-Dimethoxyphenylboronic acid
- CAS No.
- 40972-86-9
- Chemical Name:
- 2,3-Dimethoxyphenylboronic acid
- Synonyms
- AKOS BRN-0202;3-Boronoveratrole;2,3-DimethoxyphenyL;2,3-DimethoxybenzeneboronicAci;2,3-dimethoxyphenylboronci acid;2,3-DIMETHOXYPHENYLBORONIC ACID;2,3-DIMETHOXYBENZENEBORONIC ACID;2,3-DiMethoxyphenylboronic acid 97%;B-(2,3-Dimethoxy-phenyl)boronic acid;2,3-Dimethoxyphenylboronic acid ,98%
- CBNumber:
- CB6728027
- Molecular Formula:
- C8H11BO4
- Molecular Weight:
- 181.98
- MDL Number:
- MFCD02683112
- MOL File:
- 40972-86-9.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Melting point | 67-71 °C (lit.) |
|---|---|
| Boiling point | 347.9±52.0 °C(Predicted) |
| Density | 1.19±0.1 g/cm3(Predicted) |
| storage temp. | Inert atmosphere,2-8°C |
| pka | 8.12±0.58(Predicted) |
| form | powder to crystal |
| color | White to Almost white |
| BRN | 3051295 |
| InChI | InChI=1S/C8H11BO4/c1-12-7-5-3-4-6(9(10)11)8(7)13-2/h3-5,10-11H,1-2H3 |
| InChIKey | VREWSCMOGIXMDQ-UHFFFAOYSA-N |
| SMILES | B(C1=CC=CC(OC)=C1OC)(O)O |
| CAS DataBase Reference | 40972-86-9(CAS DataBase Reference) |
| UNSPSC Code | 12352103 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P280a-P304+P340-P305+P351+P338-P405-P501a | |||||||||
| PPE | Eyeshields, Gloves, type N95 (US) | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 36/37/38 | |||||||||
| Safety Statements | 26-36/37/39-36/37-37 | |||||||||
| WGK Germany | 3 | |||||||||
| Hazard Note | Irritant/Keep Cold | |||||||||
| HazardClass | IRRITANT | |||||||||
| HS Code | 29319090 | |||||||||
| Storage Class | 11 - Combustible Solids | |||||||||
| NFPA 704 |
|
2,3-Dimethoxyphenylboronic acid price More Price(78)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 557730 | 2,3-Dimethoxyphenylboronic acid 97% | 40972-86-9 | 5g | $89.2 | 2026-04-30 | Buy |
| TCI Chemical | D3853 | 2,3-Dimethoxyphenylboronic Acid (contains varying amounts of Anhydride) | 40972-86-9 | 1g | $18 | 2026-04-30 | Buy |
| TCI Chemical | D3853 | 2,3-Dimethoxyphenylboronic Acid (contains varying amounts of Anhydride) | 40972-86-9 | 5g | $54 | 2026-04-30 | Buy |
| Usbiological | 273035 | 2,3-Dimethoxyphenylboronic acid | 40972-86-9 | 1g | $322 | 2026-06-03 | Buy |
| Usbiological | 273035 | 2,3-Dimethoxyphenylboronic acid | 40972-86-9 | 2g | $438 | 2026-06-03 | Buy |
2,3-Dimethoxyphenylboronic acid Chemical Properties, Uses, Production
Chemical Properties
Off-white Cryst
Uses
suzuki reaction
General Description
2,3-Dimethoxyphenylboronic acid is a useful research chemical for organic synthesis and other chemical processes.
Synthesis
91-16-7
121-43-7
40972-86-9
To a solution of N,N,N',N'-tetramethylethylenediamine (6.1 mL, 40.5 mmol) in diethyl ether (100 mL) was added n-butyllithium (26 mL, 1.6 M in hexane, 41.6 mmol) dropwise at 0° C. After 30 min the reaction mixture was cooled to -78° C., 1,2-dimethoxybenzene (5.0 g, 36.4 mmol) and stirred for 3 h at this temperature. Subsequently, trimethyl borate (9.7 mL, 86.4 mmol) was added, the cold bath was removed and the reaction mixture was stirred at room temperature for 18 hours. After completion of the reaction, the mixture was cooled to 0 °C, 150 mL of aqueous 2 M hydrochloric acid was added and stirred for 3 hours. The mixture was extracted with ethyl acetate (3 x 20 mL), the organic layers were combined, dried over magnesium sulfate, filtered, and concentrated in vacuum to afford 2,3-dimethoxyphenylboronic acid (1 g, 37% yield) as white crystals. 6-Bromo-2,2,4-trimethyl-1,2-dihydroquinoline (256 mg, 1.02 mmol) and 2,3-dimethoxyphenylboronic acid (370 mg, 2.03 mmol) were dissolved in DMSO (2 mL), and 2 M aqueous K3PO4 (1 mL) was added, followed by PdCl2 (dppf) (50 mg). The mixture was transferred to a microwave reaction tube and microwave irradiated at 120 °C for 15 min. After completion of the reaction, it was cooled to room temperature and the crude product was purified by column chromatography to afford 6-(2,3-dimethoxyphenyl)-2,2,4-trimethyl-1,2-dihydroquinoline (190 mg, 61% yield) as a white solid. The product was brominated with N-bromosuccinimide, followed by a coupling reaction with 2-phenylethanethiol as described in Example 7 to give 45 mg of 2,3-dimethoxyphenylboronic acid as an oil.
References
[1] Chemical Communications, 1999, # 22, p. 2259 - 2260
[2] Patent: WO2004/18429, 2004, A2. Location in patent: Page 85
[3] Bulletin de la Societe Chimique de France, 1973, p. 767 - 769
2,3-Dimethoxyphenylboronic acid Preparation Products And Raw materials
Raw materials
1of2
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Tianjin Xinshengjiahe Technology Development Co., Ltd. | 022-83719186 13212251377 | 18522618860@163.com | China | 82 | 55 |
| Zhengzhou HQ Material Co., Ltd. | +86-0371-67759225 13526468238 | 3165471285@qq.com | China | 342 | 55 |
| Xi'an Kaixiang Photoelectric Technology Co., Ltd. | 18592059708 | sales@kxmaterials.com | China | 987 | 55 |
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Meryer (Shanghai) Chemical Technology Co., Ltd. | 4006356688 18621169109 | market03@meryer.com | China | 40202 | 62 |
| Alfa Aesar | 400-6106006 | saleschina@alfa-asia.com | China | 30103 | 84 |
| TCI (Shanghai) Development Co., Ltd. | 021-67121386 | Sales-CN@TCIchemicals.com | China | 24512 | 81 |
| Beijing HwrkChemical Technology Co., Ltd | 89508211 18501085097 | sales.bj@hwrkchemical.com | China | 9407 | 55 |
| Energy Chemical | 400-0056266 | sales8178@energy-chemical.com | China | 44850 | 61 |
| Wuhan Chemwish Technology Co., Ltd | 86-027-67849912 | sales@chemwish.com | China | 35884 | 56 |
View Latest Price from 2,3-Dimethoxyphenylboronic acid manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-09-02 | (2,3-Dimethoxyphenyl)boronic acid
40972-86-9
|
$30.00 | 1KG | 99% | Henan Fengda Chemical Co., Ltd | ||
 |
2026-07-16 | 2,3-Dimethoxyphenylboronic acid
40972-86-9
|
1KG | 98% | 1000kgs | Shaanxi Dideu New Materials Co. Ltd | ||
 |
2025-05-23 | (2,3-Dimethoxyphenyl)boronic acid
40972-86-9
|
$10.00 | 1kg | 99% | 20 ton | Hebei Zhuanglai Chemical Trading Co Ltd |
-
- (2,3-Dimethoxyphenyl)boronic acid
40972-86-9
- $30.00
- 99%
- Henan Fengda Chemical Co., Ltd
-
- 2,3-Dimethoxyphenylboronic acid
40972-86-9
- $0.00
- 98%
- Shaanxi Dideu New Materials Co. Ltd
-
- (2,3-Dimethoxyphenyl)boronic acid
40972-86-9
- $10.00
- 99%
- Hebei Zhuanglai Chemical Trading Co Ltd
