Thiazole-2-carboxylic acid
- CAS No.
- 14190-59-1
- Chemical Name:
- Thiazole-2-carboxylic acid
- Synonyms
- Thiazolic acid;2-Carboxythiazole;RARECHEM AL BE 0750;2-THIAZOLECARBOXYLIC;Thiazole formic acid;2-Carboxy-1,3-thiazole;Thiazole-2- forMic acid;Thiazole-2-carboxylicaci;thiazol-2-carboxylic acid;Thiazole-2-carboxylic acid
- CBNumber:
- CB6758187
- Molecular Formula:
- C4H3NO2S
- Molecular Weight:
- 129.14
- MDL Number:
- MFCD02094169
- MOL File:
- 14190-59-1.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Melting point | 91.6-93°C |
|---|---|
| Boiling point | 310.6±25.0 °C(Predicted) |
| Density | 1.525±0.06 g/cm3(Predicted) |
| storage temp. | -20°C |
| pka | 2.95±0.10(Predicted) |
| form | Solid |
| Appearance | White to off-white Solid |
| Water Solubility | Slightly soluble in water. |
| InChI | 1S/C4H3NO2S/c6-4(7)3-5-1-2-8-3/h1-2H,(H,6,7) |
| InChIKey | IJVLVRYLIMQVDD-UHFFFAOYSA-N |
| SMILES | OC(=O)c1nccs1 |
| CAS DataBase Reference | 14190-59-1(CAS DataBase Reference) |
| UNSPSC Code | 12352100 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P280a-P304+P340-P305+P351+P338-P405-P501a | |||||||||
| Risk Statements | 36/37/38-22 | |||||||||
| Safety Statements | 26-36/37/39-22 | |||||||||
| WGK Germany | 1 | |||||||||
| HS Code | 29349990 | |||||||||
| Storage Class | 11 - Combustible Solids | |||||||||
| NFPA 704 |
|
Thiazole-2-carboxylic acid price More Price(82)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 734748 | Thiazole-2-carboxylic acid | 14190-59-1 | 1g | $97.7 | 2026-04-30 | Buy |
| Apolloscientific | OR15912 | 1,3-Thiazole-2-carboxylic acid 97% | 14190-59-1 | 1g | $40 | 2026-06-04 | Buy |
| Apolloscientific | OR15912 | 1,3-Thiazole-2-carboxylic acid 97% | 14190-59-1 | 5g | $107 | 2026-06-04 | Buy |
| Apolloscientific | OR15912 | 1,3-Thiazole-2-carboxylic acid 97% | 14190-59-1 | 10g | $128 | 2026-06-04 | Buy |
| Apolloscientific | OR15912 | 1,3-Thiazole-2-carboxylic acid 97% | 14190-59-1 | 25g | $281 | 2026-06-04 | Buy |
Thiazole-2-carboxylic acid Chemical Properties, Uses, Production
Chemical Properties
Beige to light yellow powder
Uses
Thiazole-2-carboxylic acid is an important raw material and intermediate used in organic synthesis, pharmaceuticals, agrochemicals and dyestuff.
Synthesis
14527-42-5
14190-59-1
General procedure for the synthesis of thiazole-2-carboxylic acid from ethyl 2-thiazolecarboxylate: 2N aqueous KOH solution (3.5 mL, 5 eq.) was added to a solution of ethyl 2-thiazolecarboxylate (213 mg, 1.355 mmol) in ethanol (3 mL) at 116 °C. The reaction mixture was stirred at room temperature for 2 hours and then acidified with 2N HCl (3.5 mL). The acidified mixture was allowed to stand overnight and needle-like crystals were precipitated and collected by filtration to give thiazole-2-carboxylic acid (43.3 mg, 25% yield).
References
[1] Patent: US2007/185056, 2007, A1. Location in patent: Page/Page column 49
[2] Helvetica Chimica Acta, 1945, vol. 28, p. 924
[3] Patent: WO2008/76243, 2008, A2. Location in patent: Page/Page column 75
[4] Patent: WO2008/85316, 2008, A1. Location in patent: Page/Page column 73
[5] Patent: WO2006/138373, 2006, A2. Location in patent: Page/Page column 128-129
Thiazole-2-carboxylic acid Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Meryer (Shanghai) Chemical Technology Co., Ltd. | 4006356688 18621169109 | market03@meryer.com | China | 40202 | 62 |
| Alfa Aesar | 400-6106006 | saleschina@alfa-asia.com | China | 30103 | 84 |
| Energy Chemical | 400-0056266 | sales8178@energy-chemical.com | China | 44850 | 61 |
| Wuhan Chemwish Technology Co., Ltd | 86-027-67849912 | sales@chemwish.com | China | 35884 | 56 |
| Capot Chemical Co., Ltd | +86 (0) 571 85 58 67 18 | China | 18187 | 66 | |
| JinYan Chemicals(ShangHai) Co.,Ltd. | 13817811078 | sales@jingyan-chemical.com | China | 9963 | 60 |
| Jia Xing Isenchem Co.,Ltd | 0573-85285100 18627885956 | isenchem@163.com | China | 9389 | 66 |
| Pure Chemistry Scientific Inc. | 001-857-928-2050 or 1-888-588-9418 | sales@chemreagents.com | United States | 10174 | 62 |
| Shanghai Longsheng chemical Co.,Ltd. | 58099637 13585536065 | sales@shlschem.com | China | 9880 | 59 |
View Latest Price from Thiazole-2-carboxylic acid manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-03-28 | Thiazole-2-carboxylic acid
14190-59-1
|
25kg | 98% | PNP Biotech Co. Ltd | |||
 |
2022-01-27 | Thiazole-2-carboxylic acid
14190-59-1
|
1KG | 98.5% | 100 tons | Honest Joy Holdings Limited | ||
 |
2020-01-13 | THIAZOLE-2-CARBOXYLIC ACID
14190-59-1
|
$9.80 | 1KG | ≥98% | 20 tons | Career Henan Chemical Co |
-
- Thiazole-2-carboxylic acid
14190-59-1
- $0.00
- 98%
- PNP Biotech Co. Ltd
-
- Thiazole-2-carboxylic acid
14190-59-1
- $0.00
- 98.5%
- Honest Joy Holdings Limited
-
- THIAZOLE-2-CARBOXYLIC ACID
14190-59-1
- $9.80
- ≥98%
- Career Henan Chemical Co
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