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4-Chloropicolinaldehyde

4-Chloropicolinaldehyde Structure
4-Chloropicolinaldehyde structure
CAS No.
63071-13-6
Chemical Name:
4-Chloropicolinaldehyde
Synonyms
4-Chloro-2-pyridinecarboxaldehyde;oropyridine-2-carbaL;4-Chloropicolaldehyde;4-Chloropicolinaldehyde;Picolinaldehyde, 4-chloro-;4-Chloro-2-aldehyde pyridine;4-chloropyridine-2-carbaldehyde;4-chloro-2-pyridinecarbaldehyde;4-CHLOROPYRIDINE-2-CARBOXALDEHYDE;2-Pyridinecarboxaldehyde,4-chloro-
CBNumber:
CB6782472
Molecular Formula:
C6H4ClNO
Molecular Weight:
141.56
MDL Number:
MFCD07437896
MOL File:
63071-13-6.mol
MSDS File:
SDS
Last updated:2026-09-12 18:54:24
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4-Chloropicolinaldehyde Properties

Melting point 32-34°
Boiling point 206℃
Density 1.332
Flash point 79℃
storage temp. Inert atmosphere,Store in freezer, under -20°C
solubility Chloroform (Slightly), Methanol (Slightly)
pka 1.78±0.10(Predicted)
form Solid
color Off-White to Pale Yellow
Stability Air Sensitive

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H319-H315-H335-H302
Precautionary statements  P264-P270-P301+P312-P330-P501-P264-P280-P305+P351+P338-P337+P313P-P264-P280-P302+P352-P321-P332+P313-P362
Risk Statements  43
Safety Statements  36/37
HazardClass  IRRITANT
HS Code  2933399990

4-Chloropicolinaldehyde price More Price(40)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Usbiological 269065 4-Chloro-2-pyridinecarbaldehyde Asreported 63071-13-6 5g $470 2026-06-03 Buy
Usbiological 269065 4-Chloro-2-pyridinecarbaldehyde Asreported 63071-13-6 10g $645 2026-06-03 Buy
Usbiological 269065 4-Chloro-2-pyridinecarbaldehyde Asreported 63071-13-6 25g $1021 2026-06-03 Buy
Usbiological 269065 4-Chloro-2-pyridinecarbaldehyde Asreported 63071-13-6 50g $1426 2026-06-03 Buy
Usbiological 269065 4-Chloro-2-pyridinecarbaldehyde Asreported 63071-13-6 100g $2018 2026-06-03 Buy
Product number Packaging Price Buy
269065 5g $470 Buy
269065 10g $645 Buy
269065 25g $1021 Buy
269065 50g $1426 Buy
269065 100g $2018 Buy

4-Chloropicolinaldehyde Chemical Properties, Uses, Production

Uses

4-Chloro-2-pyridinecarboxaldehyde is a useful synthetic intermediate. It is used in the synthesis of 2,2''-bipyridines, (chloropyridyl)(pyridyl)ethylamine and aryl and heteroaryl fluoromethyl ketones.

Synthesis

Methyl 4-chloropicolinate

24484-93-3

4-CHLOROPICOLINALDEHYDE

63071-13-6

General procedure for the synthesis of 4-chloro-2-pyridinecarboxaldehyde from methyl 4-chloropyridinecarboxylate: to a solution of methyl 4-chloropyridinecarboxylate (2.5 g, 14.6 mmol) in anhydrous THF (100 mL) was added slowly and dropwise diisobutylaluminum hydride (1.0 M solution in THF, 29.1 mmol) at -78 °C and the reaction was stirred in an argon atmosphere at that temperature mixture for 2 hours. Upon completion of the reaction, the reaction was quenched with methanol (MeOH) at -78 °C, followed by the addition of potassium sodium tartrate solution (1.0 M, 180 mL), and the mixture was stirred and gradually warmed to room temperature over a period of 1 hour. The reaction mixture was diluted with ethyl acetate (EtOAc, 60 mL) and the organic layer was separated, washed with saturated saline and dried with anhydrous sodium sulfate. The solvent was removed by mild decompression distillation at room temperature to afford the target product 4-chloro-2-pyridinecarboxaldehyde (1.87 g, 91% yield), which solidified to light yellow crystals after standing at room temperature.

References

[1] Patent: US2004/186114, 2004, A1. Location in patent: Page/Page column 69; 70
[2] Patent: EP1897880, 2008, A1. Location in patent: Page/Page column 16
[3] Inorganic Chemistry, 2013, vol. 52, # 11, p. 6481 - 6501
[4] Bulletin of the Chemical Society of Japan, 2015, vol. 88, # 6, p. 784 - 791

4-Chloropicolinaldehyde Preparation Products And Raw materials

Raw materials

Methyl 4-chloropicolinate (4-Chloro-pyridin-2-yl)-methanol Diisobutylaluminium hydride Tetrahydrofuran Methanol
Potassium sodium tartrate

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Preparation Products

4-Chloropicolinaldehyde Suppliers

Global Suppliers ( 159)
Supplier Tel Email Country ProdList Advantage
PharmaBlock Sciences (Nanjing),Inc. 025-86918202 4000255188 sales@pharmablock.com China 5000 55
Energy Chemical 400-0056266 sales8178@energy-chemical.com China 44850 61
Wuhan Chemwish Technology Co., Ltd 86-027-67849912 sales@chemwish.com China 35884 56
Jia Xing Isenchem Co.,Ltd 0573-85285100 18627885956 isenchem@163.com China 9389 66
ChengDu TongChuangYuan Pharmaceutical Co.Ltd 28-83379370 13880556291 tcy@tcypharm.com China 509 57
Tetranov Biopharm 13526569071 sales@leadmedpharm.com China 7881 64
Accela ChemBio Co.,Ltd. 021-50795510 4000665055 marketing@accelachem.com China 10972 64
Changzhou Woyan Chemical Co., Ltd. 0510-83782303 13771177691 sales@itppharm.com China 91 62
Shanghai Sunway Pharmaceutical Technology Co., Ltd 13761987713 hxzheng@sunwaypharm.cn China 8663 57
Shanghai yirong biology science and technology co., ltd 18049974220 3060526242@qq.com China 999 60
Supplier Advantage
PharmaBlock Sciences (Nanjing),Inc. 55
Energy Chemical 61
Wuhan Chemwish Technology Co., Ltd 56
Jia Xing Isenchem Co.,Ltd 66
ChengDu TongChuangYuan Pharmaceutical Co.Ltd 57
Tetranov Biopharm 64
Accela ChemBio Co.,Ltd. 64
Changzhou Woyan Chemical Co., Ltd. 62
Shanghai Sunway Pharmaceutical Technology Co., Ltd 57
Shanghai yirong biology science and technology co., ltd 60

View Latest Price from 4-Chloropicolinaldehyde manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
4-CHLOROPICOLINALDEHYDE pictures 2026-08-20 4-CHLOROPICOLINALDEHYDE
63071-13-6
 $1.10 1g 99.00% 100 Tons Min Dideu Industries Group Limited
4-CHLOROPICOLINALDEHYDE pictures 2023-03-19 4-CHLOROPICOLINALDEHYDE
63071-13-6
 1kg 98% Min 1000kg LY Global chemicals co.,ltd .
4-CHLOROPICOLINALDEHYDE pictures 2020-01-09 4-CHLOROPICOLINALDEHYDE
63071-13-6
 $1.00 1ASSAYS 85.0-99.8% 20tons Career Henan Chemical Co

4-Chloropicolinaldehyde Spectrum

4-CHLOROPICOLINALDEHYDE(63071-13-6)1HNMR

63071-13-6 (4-Chloropicolinaldehyde) Related Search:

Tetrachloropyridine-2-carboxylic acid 4-Chloropyridine-2-carboxylic acid 4-Chloropyridine-2-carboxamide dimethyl 4-chloropyridine-2,6-dicarboxylate 4-Chloro-pyridine-2-carboxylic acid hydrazide
2,3,5-Trichloropyridine-4-carboxaldehyde 2-Chloropyridine-5-carbaldehyde 2-Chloroisonicotinaldehyde 6-Chloropicolinaldehyde 2-Chloro-3-pyridinecarboxaldehyde
4-Chloro-N-methylpicolinamide 3,4,5-Trichloropyridine-2-carboxylic acid 4-Chloropyridine-2,6-dicarbohydrazide 2 6-Dichloropyridine-3-carboxaldehyde 3,4,5-Trichloro-6-hydroxypyridine-2-carboxylic acid
Diethyl 4-chloro-2,6-pyridinedicarboxylate Ethyl 3,4,5,6-tetrachloropyridine-2-carboxylate Methyl 3,4,5,6-tetrachloropyridine-2-carboxylate

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4-CHLOROPYRIDINE-2-CARBOXALDEHYDE 4-chloro-2-pyridinecarbaldehyde 4-Chloropyridin-2-ylcarboxaldehyde 2-Pyridinecarboxaldehyde,4-chloro- Picolinaldehyde, 4-chloro- 4-chloropyridine-2-carbaldehyde oropyridine-2-carbaL 4-CHLOROPICOLINALDEHYDE ISO 9001：2015 REACH 4-Chloropyridine-2-carbaldehyde4-Chloropyridine-2-carbaldehyde 4-Chloro-2-aldehyde pyridine 4-Chloropicolaldehyde 4-Chloro-2-pyridinecarboxaldehyde 4-Chloropicolinaldehyde 63071-13-6 Pyridines