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1H-Pyrazolo[3,4-b]pyridin-3-amine

1H-Pyrazolo[3,4-b]pyridin-3-amine Structure
1H-Pyrazolo[3,4-b]pyridin-3-amine structure
CAS No.
6752-16-5
Chemical Name:
1H-Pyrazolo[3,4-b]pyridin-3-amine
Synonyms
NSC 48665;OTAVA-BB BB7110952567;3-AMino-7-azaindazole;3-Amino-7-aza-1H-indazole;1H-pyrazolo[3,4-b]pyridin...;3-Aminopyrazol[3,4-b]pyridine;3-AMINOPYRAZOLO[3,4-B]PYRIDINE;3-Aminopyrazolo[3,4-β]pyridine;1H-Pyrazol[3,4]pyridin-3-amine;1H-PYRAZOLO[3,4-B]PYRIDIN-3-AMINE
CBNumber:
CB7186251
Molecular Formula:
C6H6N4
Molecular Weight:
134.14
MDL Number:
MFCD04113611
MOL File:
6752-16-5.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-05-28 02:39:13
Request For Quotation

1H-Pyrazolo[3,4-b]pyridin-3-amine Properties

Melting point 189-192°C
Boiling point 315.3±25.0 °C(Predicted)
Density 1.61±0.1 g/cm3(Predicted)
storage temp. Keep in dark place,Inert atmosphere,Room temperature
solubility DMSO, Methanol
form Solid
pka 7.17±0.20(Predicted)
color Yellow
InChI 1S/C6H6N4/c7-5-4-2-1-3-8-6(4)10-9-5/h1-3H,(H3,7,8,9,10)
InChIKey LUAQTQAFUORQHV-UHFFFAOYSA-N
SMILES Nc1n[nH]c2ncccc12
CAS DataBase Reference 6752-16-5(CAS DataBase Reference)
UNSPSC Code 12352100
NACRES NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)  Skull and Crossbones (GHS06)
GHS06
Signal word  Danger
Hazard statements  H301
Precautionary statements  P301+P310
Hazard Codes  Xi,T
Risk Statements  25
Safety Statements  45
RIDADR  2811
WGK Germany  1
HazardClass  IRRITANT
PackingGroup  Ⅲ
HS Code  29331990
Storage Class 6.1C - Combustible acute toxic Cat.3
toxic compounds or compounds which causing chronic effects
Hazard Classifications Acute Tox. 3 Oral

1H-Pyrazolo[3,4-b]pyridin-3-amine price More Price(88)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 729469 3-Amino-7-azaindazole 97% 6752-16-5 500mg $98.6 2026-04-30 Buy
Usbiological 286486 1H-Pyrazolo[3,4-b]pyridine-3-amine Asreported 6752-16-5 1g $345 2026-06-03 Buy
Usbiological 286486 1H-Pyrazolo[3,4-b]pyridine-3-amine Asreported 6752-16-5 2g $475 2026-06-03 Buy
Usbiological 286486 1H-Pyrazolo[3,4-b]pyridine-3-amine Asreported 6752-16-5 5g $638 2026-06-03 Buy
Usbiological 286486 1H-Pyrazolo[3,4-b]pyridine-3-amine Asreported 6752-16-5 10g $858 2026-06-03 Buy
Product number Packaging Price Buy
729469 500mg $98.6 Buy
286486 1g $345 Buy
286486 2g $475 Buy
286486 5g $638 Buy
286486 10g $858 Buy

1H-Pyrazolo[3,4-b]pyridin-3-amine Chemical Properties, Uses, Production

Chemical Properties

Yellow Solid

Synthesis

2-Chloro-3-cyanopyridine

6602-54-6

1H-Pyrazolo[3,4-b]pyridin-3-amine

6752-16-5

General procedure for the synthesis of 3-amino-1H-pyrazolo[3,4-b]pyridine from 2-chloro-3-cyanopyridine: 2-chloro-3-cyanopyridine (1.4 mmol) was dissolved in ethanol (10 mL) in a microwave reactor tube, followed by the addition of 5 equivalents of hydrazine hydrate (NH2NH2-H2O). The reaction mixture was placed in a microwave reactor and radiantly heated at 170 °C for 10 min. Upon completion of the reaction, the solvent was removed by rotary evaporator to afford 3-amino-1H-pyrazolo[3,4-b]pyridine in quantitative yield.

References

[1] Patent: WO2007/59219, 2007, A1. Location in patent: Page/Page column 56
[2] Chemical Communications, 2014, vol. 50, # 85, p. 12911 - 12914
[3] Canadian Journal of Chemistry, 1988, vol. 66, # 3, p. 420-428
[4] Journal of Heterocyclic Chemistry, 2012, vol. 49, # 4, p. 763 - 767
[5] European Journal of Medicinal Chemistry, 2013, vol. 68, p. 361 - 371

1H-Pyrazolo[3,4-b]pyridin-3-amine Preparation Products And Raw materials

Raw materials

3-Aminopyrazole Ethanol Zinc chloride Palladium Nitric acid
1,1,3,3-Tetramethoxypropane Sulfuric acid 2-Chloro-3-cyanopyridine HYDRAZINE

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Preparation Products

1H-Pyrazolo[3,4-b]pyridin-3-amine Suppliers

Global Suppliers ( 160)
Supplier Tel Email Country ProdList Advantage
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
Meryer (Shanghai) Chemical Technology Co., Ltd. 4006356688 18621169109 market03@meryer.com China 40202 62
Energy Chemical 400-0056266 sales8178@energy-chemical.com China 44850 61
Wuhan Chemwish Technology Co., Ltd 86-027-67849912 sales@chemwish.com China 35884 56
Capot Chemical Co., Ltd +86 (0) 571 85 58 67 18 China 18187 66
Jia Xing Isenchem Co.,Ltd 0573-85285100 18627885956 isenchem@163.com China 9389 66
Shangchem Co., Ltd. +86-21-68182121 China 881 52
Shanghai Hanhong Scientific Co.,Ltd. 021-54306202 13764082696 info@hanhongsci.com China 42917 64
Chemsky（shanghai）International Co.,Ltd. 021-50135380 shchemsky@sina.com China 32273 50
ChangZhou SIDU chemical Co., Ltd. 0519-81291281 18015082300 siduchem@hotmail.com China 274 62
Supplier Advantage
J & K SCIENTIFIC LTD. 76
Meryer (Shanghai) Chemical Technology Co., Ltd. 62
Energy Chemical 61
Wuhan Chemwish Technology Co., Ltd 56
Capot Chemical Co., Ltd 66
Jia Xing Isenchem Co.,Ltd 66
Shangchem Co., Ltd. 52
Shanghai Hanhong Scientific Co.,Ltd. 64
Chemsky（shanghai）International Co.,Ltd. 50
ChangZhou SIDU chemical Co., Ltd. 62

View Latest Price from 1H-Pyrazolo[3,4-b]pyridin-3-amine manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
1H-Pyrazolo[3,4-b]pyridin-3-amine pictures 2026-08-20 1H-Pyrazolo[3,4-b]pyridin-3-amine
6752-16-5
 $1.10 1g 99.00% 100 Tons Min Dideu Industries Group Limited
1H-Pyrazolo[3,4-b]pyridin-3-amine pictures 2019-07-06 1H-Pyrazolo[3,4-b]pyridin-3-amine
6752-16-5
 $1.00 1kg 98% 100KG Career Henan Chemical Co

1H-Pyrazolo[3,4-b]pyridin-3-amine Spectrum

1H-Pyrazolo[3,4-b]pyridin-3-amine(6752-16-5)1HNMR

6752-16-5 (1H-Pyrazolo[3,4-b]pyridin-3-amine) Related Search:

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2H-pyrazolo[3,4-b]pyridin-3-amine 1H-Pyrazolo[3,4-β]pyridin-3-amine 1H-Pyrazolo[3,4-β]pyridin-3-ylamine 3-Amino-1H-pyrazolo[3,4-β]pyridine 3-Aminopyrazolo[3,4-β]pyridine NSC 48665 OTAVA-BB BB7110952567 1H-PYRAZOLO[3,4-B]PYRIDIN-3-AMINE 1H-PYRAZOLO[3,4-B]PYRIDIN-3-YLAMINE 3-AMINOPYRAZOLO[3,4-B]PYRIDINE 1H-Pyrazolo[3,4-b]pyridine-3-amine 1H-Pyrazol[3,4]pyridin-3-amine 3-Amino-1H-pyrazolo[3,4-b]pyridine 1H-Pyrazolo[3,4-b]pyridin-3-ylamine ,97% 3-Aminopyrazol[3,4-b]pyridine 3-AMino-7-azaindazole 3-Amino-7-aza-1H-indazole 1H-Pyrazolo[3,4-b]pyridin-3-amine ,97% 1H-pyrazolo[3,4-b]pyridin... 1H-pyrazolo[3,4-b]pyridin-3-amine(SALTDATA: FREE) 1H-Pyrazolo[3,4-b]pyridin-3-amine ISO 9001：2015 REACH 6752-16-5 1H-Pyrazolo[3,4-b]pyridin-3-amine 6752-16-5 Heterocycles Fused Ring Systems Chemical Amines Amines blocks Pyridines Heterocycles series