4,5-Dimethoxy-2-nitrobenzoic acid
- CAS No.
- 4998-07-6
- Chemical Name:
- 4,5-Dimethoxy-2-nitrobenzoic acid
- Synonyms
- 6-NITROVERATRIC ACID;4-Nitroveratic acid;RARECHEM AL BO 1523;6-Nitroveratriceacid;4,5-Dimethoxy-2-nitr;6-Nitroveratricacid,99%;6-NITROVERATRIC ACID 99%;4,5-Dimethoxy-2-nitrobenzoic;4,5-dimethoxy-2-nitrobenzoate;3,4-DIMETHOXY-6-NITROBENZOIC ACID
- CBNumber:
- CB7364668
- Molecular Formula:
- C9H9NO6
- Molecular Weight:
- 227.17
- MDL Number:
- MFCD00014697
- MOL File:
- 4998-07-6.mol
- MSDS File:
- SDS
| Melting point | 195-197 °C(lit.) |
|---|---|
| Boiling point | 368.87°C (rough estimate) |
| Density | 1.4777 (rough estimate) |
| refractive index | 1.5800 (estimate) |
| storage temp. | Sealed in dry,Room Temperature |
| solubility | Acetonitrile (Slightly), DMSO (Slightly), Methanol (Slightly) |
| pka | 2.34±0.25(Predicted) |
| form | Crystalline Powder |
| color | Yellow |
| Water Solubility | Insoluble in water. Soluble in DMSO and methanol. Solubility in hot 1mol/L NaOH (almost transparency). |
| BRN | 2123903 |
| InChI | InChI=1S/C9H9NO6/c1-15-7-3-5(9(11)12)6(10(13)14)4-8(7)16-2/h3-4H,1-2H3,(H,11,12) |
| InChIKey | WWCMFGBGMJAJRX-UHFFFAOYSA-N |
| SMILES | C(O)(=O)C1=CC(OC)=C(OC)C=C1[N+]([O-])=O |
| CAS DataBase Reference | 4998-07-6(CAS DataBase Reference) |
| FDA UNII | ND4L58599P |
| UNSPSC Code | 12352100 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
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|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P264-P271-P280-P302+P352-P305+P351+P338 | |||||||||
| target organs | Respiratory system | |||||||||
| PPE | dust mask type N95 (US), Eyeshields, Gloves | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 36/37/38 | |||||||||
| Safety Statements | 26-37/39 | |||||||||
| WGK Germany | 3 | |||||||||
| HS Code | 29189900 | |||||||||
| Storage Class | 11 - Combustible Solids | |||||||||
| Hazard Classifications | Eye Irrit. 2 Skin Irrit. 2 STOT SE 3 |
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| NFPA 704 |
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4,5-Dimethoxy-2-nitrobenzoic acid price More Price(71)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 329231 | 4,5-Dimethoxy-2-nitrobenzoic acid 99% | 4998-07-6 | 5g | $67.1 | 2023-06-20 | Buy |
| TCI Chemical | D2628 | 4,5-Dimethoxy-2-nitrobenzoic Acid >98.0%(GC)(T) | 4998-07-6 | 5g | $53 | 2026-04-30 | Buy |
| TCI Chemical | D2628 | 4,5-Dimethoxy-2-nitrobenzoic Acid >98.0%(GC)(T) | 4998-07-6 | 25g | $162 | 2026-04-30 | Buy |
| TRC | TRC-D460695-500G | 4,5-Dimethoxy-2-nitrobenzoic Acid | 4998-07-6 | 500g | $2521 | 2026-06-03 | Buy |
| TRC | TRC-D460695-250G | 4,5-Dimethoxy-2-nitrobenzoic Acid | 4998-07-6 | 250g | $1541 | 2026-06-03 | Buy |
4,5-Dimethoxy-2-nitrobenzoic acid Chemical Properties,Uses,Production
Chemical Properties
Yellow crystalline powder
Uses
4,5-Dimethoxy-2-nitrobenzoic acid was used in the synthesis of 4,5-dimethoxy-2-nitrobenzamide and 6,7-dimethoxyquinazoline derivatives.
Application
4,5-dimethoxy-2-nitrobenzoic acid in the reaction with organotin oxides/halides yields the organotin carboxylates in anhydrous toluene. The resulting triorganotin carboxylates are one-dimensional polymers that are solid with trigonal bipyramidal geometry, while in solution, they are tetrahedral. Reaction of di-n-butyl tin oxide with 4,5-dimethoxy-2-nitrobenzoic acid yields Tetrabutylbis(4,5-dimethoxy-2-nitro benzoate)Distannoxane Dimer crystallizes as the usual dicarboxylatotetraorganodistannoxane dimer[1-2].
General Description
4,5-Dimethoxy-2-nitrobenzoic acid is a nitroaromatic compound.
Synthesis
In 3,4-dimethoxy-6-nitrobenzaldehyde (10 g)The reaction medium (20 mL of water, 30 mL of methanol)Acetic acid (3.5 mL), 30% hydrogen peroxide (9 mL)Stir well and add sodium chlorite (content 80%, 9g) in water (5mL); Stirring warming to about 50, monitoring the reaction, After the reaction was completed, sodium bisulfite (10.5 g) was added to quench the reaction, The solvent was evaporated to dryness, the product was dissolved in a solution of sodium hydroxide (6g × 10mL)Filtered to remove impurities, the filtrate was added sulfuric acid to pH 1 precipitated product, Filter and dry and obtained product 4,5-Dimethoxy-2-nitrobenzoic acid 10g (93% yield, high-performance liquid chromatography 99.5% purity).
References
[1] Farooq Ali Shah. “Synthesis, Characterization and Crystal Structure of Tetrabutylbis(4,5-dimethoxy-2-nitro benzoato)Distannoxane Dimer.” Journal of Chemical Crystallography 41 9 (2011).
[2] F. A. Shah. “Organotin(IV) complexes of 4,5-dimethoxy-2-nitrobenzoic acid: Synthesis, characterization, and biological activity.” Russian Journal of Coordination Chemistry 35 12 (2009).
4,5-Dimethoxy-2-nitrobenzoic acid Preparation Products And Raw materials
Raw materials
1of2
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shanghai Taijilin Industrial Co., Ltd. | 02150630626 17717886015 | kate@tajilin.com | China | 1340 | 58 |
| Zibo tailize Chemical Co. , Ltd. | 0533-5200592 13173271895 | 283531267@qq.com | China | 24 | 58 |
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| 3B Pharmachem (Wuhan) International Co.,Ltd. | 18930552037 | 3bsc@sina.com | China | 15813 | 69 |
| Alfa Aesar | 400-6106006 | saleschina@alfa-asia.com | China | 30103 | 84 |
| TCI (Shanghai) Development Co., Ltd. | 021-67121386 | Sales-CN@TCIchemicals.com | China | 24512 | 81 |
| ShangHai DEMO Chemical Co.,Ltd | 400-021-7337 2355568890 | sales@demochem.com | China | 2569 | 57 |
| Energy Chemical | 400-0056266 | sales8178@energy-chemical.com | China | 44850 | 61 |
| Beijing Ouhe Technology Co., Ltd | 13552068683 13522913783 | 2355560935@qq.com | China | 11777 | 60 |
| JinYan Chemicals(ShangHai) Co.,Ltd. | 13817811078 | sales@jingyan-chemical.com | China | 9963 | 60 |
View Lastest Price from 4,5-Dimethoxy-2-nitrobenzoic acid manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-09-02 | 4,5-Dimethoxy-2-nitrobenzoic acid
4998-07-6
|
$2.00-8.00 | 1kg | 99% | Henan Fengda Chemical Co., Ltd | ||
 |
2026-06-30 | 4,5-Dimethoxy-2-nitrobenzoic acid
4998-07-6
|
1KG | 98 | 10000KGS | Shaanxi Dideu New Materials Co. Ltd | ||
 |
2025-06-20 | 4,5-Dimethoxy-2-nitrobenzoic acid
4998-07-6
|
1kg | 0.99 | 1000kg | Hebei Yanxi Chemical Co., Ltd. |
-
- 4,5-Dimethoxy-2-nitrobenzoic acid
4998-07-6
- $2.00-8.00
- 99%
- Henan Fengda Chemical Co., Ltd
-
- 4,5-Dimethoxy-2-nitrobenzoic acid
4998-07-6
- 98
- Shaanxi Dideu New Materials Co. Ltd
-
- 4,5-Dimethoxy-2-nitrobenzoic acid
4998-07-6
- $0.00
- 0.99
- Hebei Yanxi Chemical Co., Ltd.
