ChemicalBook >> CAS DataBase List >>2-(2-Aminothiazole-4-yl)-2-hydroxyiminoacetic acid

2-(2-Aminothiazole-4-yl)-2-hydroxyiminoacetic acid

2-(2-Aminothiazole-4-yl)-2-hydroxyiminoacetic acid structure

CAS No.: 66338-96-3

Chemical Name:: 2-(2-Aminothiazole-4-yl)-2-hydroxyiminoacetic acid

Synonyms: HATA;ATHAA;-2-(hydroxyimino);4-Thiazylacetic acid;Ceftazidime Impurity 21;(Z)-2-Hydroxyimino-2-(2-aminot;(2-AMINOTHIAZOL-4-YL)HYDROXYIMINO ACETIC ACID;2-(2-Amino-4-thiazolyl)-2-hydroxyiminoaceticacid;2-Amino-alpha-(hydroxyimino)-4-thiazoleaceticacid;2-(2-aminothiazole-4-yl)-z-hydroxyiminoaceticacid

CBNumber:: CB7418271

Molecular Formula:: C5H5N3O3S

Molecular Weight:: 187.18

MDL Number:: MFCD00062754

MOL File:: 66338-96-3.mol

MSDS File:: SDS

Last updated:2025-07-24 18:13:49

Product description	Number	Pack Size	Price
(Z)-2-(2-Aminothiazol-4-yl)-2-(hydroxyimino)acetic acid	118898	1.00g	$36
(Z)-2-(2-Aminothiazol-4-yl)-2-(hydroxyimino)acetic acid	118898	5.00g	$108
(Z)-2-(2-Aminothiazol-4-yl)-2-(hydroxyimino)acetic acid	118898	10.00g	$162
(Z)-2-(2-Aminothiazol-4-yl)-2-(hydroxyimino)acetic acid 98%	A92221	10g	$70
(Z)-2-(2-Aminothiazol-4-yl)-2-(hydroxyimino)acetic acid 98%	A92221	25g	$75
More product size

Request For Quotation

2-(2-Aminothiazole-4-yl)-2-hydroxyiminoacetic acid Properties

Melting point	190-192°C
Boiling point	539.4±42.0 °C(Predicted)
Density	1.92±0.1 g/cm3(Predicted)
storage temp.	Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
solubility	DMSO (Slightly, Heated)
pka	10.37±0.70(Predicted)
form	Solid
color	Pale Beige
CAS DataBase Reference	66338-96-3(CAS DataBase Reference)

SAFETY

Risk and Safety Statements

NFPA 704

	0
2		0

2-(2-Aminothiazole-4-yl)-2-hydroxyiminoacetic acid price More Price(36)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Matrix Scientific	118898	(Z)-2-(2-Aminothiazol-4-yl)-2-(hydroxyimino)acetic acid	66338-96-3	1.00g	$36	2026-05-18	Buy
Matrix Scientific	118898	(Z)-2-(2-Aminothiazol-4-yl)-2-(hydroxyimino)acetic acid	66338-96-3	5.00g	$108	2026-05-18	Buy
Matrix Scientific	118898	(Z)-2-(2-Aminothiazol-4-yl)-2-(hydroxyimino)acetic acid	66338-96-3	10.00g	$162	2026-05-18	Buy
Synthonix	A92221	(Z)-2-(2-Aminothiazol-4-yl)-2-(hydroxyimino)acetic acid 98%	66338-96-3	10g	$70	2026-05-06	Buy
Synthonix	A92221	(Z)-2-(2-Aminothiazol-4-yl)-2-(hydroxyimino)acetic acid 98%	66338-96-3	25g	$75	2026-05-06	Buy

Product number	Packaging	Price	Buy
118898	1.00g	$36	Buy
118898	5.00g	$108	Buy
118898	10.00g	$162	Buy
A92221	10g	$70	Buy
A92221	25g	$75	Buy

2-(2-Aminothiazole-4-yl)-2-hydroxyiminoacetic acid Chemical Properties,Uses,Production

Uses

(Z)-2-(2-Aminothiazol-4-yl)-2-(hydroxyimino)acetic Acidcan be used to synthesize cephalosporin derivatives and β-lactam antibiotics.

Synthesis

4-Thiazoleacetic acid, 2-amino-α-(ethoxyimino)-, (αZ)-

68401-22-9

2-(2-Aminothiazole-4-yl)-2-hydroxyiminoacetic acid

66338-96-3

GENERAL METHOD: NaOH (2.4 g, 0.06 mol) was dissolved in water (100 mL) and stirred under cooling in an ice bath. To this solution was added ethyl 2-(2-aminothiazol-4-yl)-2-(trans)-hydroxyiminoacetate or ethyl 2-(2-aminothiazol-4-yl)-2-(cis)-hydroxyiminoacetate (10.76 g, 0.05 mol). The reaction mixture was stirred at 15-20°C for 2-3 hours. After completion of the reaction, the solvent was removed by distillation under reduced pressure. The residual solid was dissolved in water (100 mL), decolorized by the addition of Norit (1.0 g) and filtered. Glacial acetic acid was slowly added dropwise to the filtrate under stirring until the pH reached neutral. The resulting precipitate was collected by filtration, washed with water and finally the product was purified by two ethanol recrystallizations.

References

[1] Polyhedron, 2015, vol. 85, p. 208 - 220

2-(2-Aminothiazole-4-yl)-2-hydroxyiminoacetic acid synthesis

Synthesis of 2-(2-Aminothiazole-4-yl)-2-hydroxyiminoacetic acid from Ethanamine, N-[(3,5-dichlorophenyl)methylene]-2,2-diethoxy-

2-(2-Aminothiazole-4-yl)-2-hydroxyiminoacetic acid Preparation Products And Raw materials

Raw materials

Ethyl 2-(2-aminothiazole-4-yl)-2-hydroxyiminoacetate 4-Thiazoleacetic acid, 2-amino-α-(ethoxyimino)-, (αZ)- Water Sodium hydroxide

Preparation Products

(Z)-2-(2-AMinothiazol-4-yl)-N-(2-hydroxyethyl)-2-(hydroxyiMino)acetaMide

2-(2-Aminothiazole-4-yl)-2-hydroxyiminoacetic acid Suppliers

Global( 137)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	info@tianfuchem.com	China	21588	55
Standardpharm Co. Ltd.	86-714-3992388	overseasales1@yongstandards.com	United States	14332	58
Alchem Pharmtech,Inc.	8485655694	sales@alchempharmtech.com	United States	63687	58
CONIER CHEM AND PHARMA LIMITED	+8618523575427	sales@conier.com	China	49977	58
career henan chemical co	+86-0371-86658258 +8613203830695	factory@coreychem.com	China	29794	58
SIMAGCHEM CORP	+86-5922680277 +86-13806087780	sale@simagchem.com	China	17346	58
AFINE CHEMICALS LIMITED	+86-0571-85134551	sales@afinechem.com	China	15082	58
Dayang Chem (Hangzhou) Co.,Ltd.	+86-0571-88938639 +8617705817739	info@dycnchem.com	China	52705	58
Hefei TNJ Chemical Industry Co.,Ltd.	+86-0551-65418684 +8618949823763	sales@tnjchem.com	China	25356	58
GIHI CHEMICALS CO.,LIMITED	+86-571-86217390; +8618058761490	info@gihichemicals.com	China	49967	58

Supplier	Advantage
Henan Tianfu Chemical Co.,Ltd.	55
Standardpharm Co. Ltd.	58
Alchem Pharmtech,Inc.	58
CONIER CHEM AND PHARMA LIMITED	58
career henan chemical co	58
SIMAGCHEM CORP	58
AFINE CHEMICALS LIMITED	58
Dayang Chem (Hangzhou) Co.,Ltd.	58
Hefei TNJ Chemical Industry Co.,Ltd.	58
GIHI CHEMICALS CO.,LIMITED	58

View Lastest Price from 2-(2-Aminothiazole-4-yl)-2-hydroxyiminoacetic acid manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2020-01-01	2-(2-Aminothiazole-4-yl)-2-hydroxyiminoacetic acid 66338-96-3	US $7.00 / KG	1KG	99%	100KG	Career Henan Chemical Co

2-(2-Aminothiazole-4-yl)-2-hydroxyiminoacetic acid
66338-96-3
US $7.00 / KG
99%
Career Henan Chemical Co

2-(2-Aminothiazole-4-yl)-2-hydroxyiminoacetic acid Spectrum

2-(2-Aminothiazole-4-yl)-2-hydroxyiminoacetic acid(66338-96-3)¹HNMR

66338-96-3(2-(2-Aminothiazole-4-yl)-2-hydroxyiminoacetic acid)Related Search:

2-Aminothiazole-4-acetic acid Molasses 2-(2-Aminothiazol-4-yl)glyoxylic acid Cefotaxime sodium Cefotaxime

2-(2-Aminothiazole-4-yl)-2-methoxyiminoacetic acid Glycine Ethyl 2-(2-aminothiazole-4-yl)-2-hydroxyiminoacetate 2-(TRITYLAMINO)-ALPHA-(METHOXYIMINO)-4-THIAZOLEACETIC ACID HYDROCHLORIDE (Z)-2-(2-Aminothiazol-4-yl)-2-(1-carboxy-1-methyl)ethoxyiminoacetic acid

(Z)-2-(2-Aminothiazol-4-yl)-2-(tert-butoxycarbonylmethoxyimino)acetic acid (Z)-2-(5-AMINO-1,2,4-THIADIAZOL-3-YL)-2-METHOXYIMINO ACETIC ACID Ethyl 2-(2-aminothiazole-4-yl)-2-(1-tert-butoxycarbonyl-1-methylethoxyimino)acetate Ethyl 2-(2-aminothiazol-4-yl)-2-methoxyiminoacetate 2-(2-Formamidothiazole-4-yl)-2-methoxyimino acetic acid

(Z)-2-(Methoxycarbonylmethoxyimino)-2-(2-aminothiazol-4-yl)acetic acid 2-Aminothiazole (Z)-[2-(Chloroacetamido)thiazole-4-yl]methoxyiminoacetic acid

1of4

-2-(hydroxyimino) 2-(2-Amino-4-thiazolyl)-2-hydroxyiminoaceticacid 2-(2-aminothiazole-4-yl)-z-hydroxyiminoaceticacid 2-Amino-alpha-(hydroxyimino)-4-thiazoleaceticacid 2-(2-AMINOTHIAZOLE-4-YL)-2-HYDROXYIMINOACETIC ACID (2-AMINOTHIAZOL-4-YL)HYDROXYIMINO ACETIC ACID (Z)-2-HYDROXYIMINO-2-(2-AMINOTHIAZOL-4-YL)ACETIC ACID (Z)-2-HYDROXYIMINO-2-(2-AMINOTHIAZOLE-4-YL)ACETIC ACID (Z)-2-(2-aminothiazol-4-yl)-2-hydroxyiminoacetic acid 2-(2-Aminothiazole-4-yl)-2-hydroxyiminoacetic acid(HATA) (Z)-2-Hydroxyimino-2-(2-aminothiazol-4-yl)Acetic acid anhydrous ATHA ( Z )-2-(2-Aminothiazol-4-yl)-2-hydroxyiminoacetic acid (Z)-2-Hydroxyimino-2-(2-aminot (Z)-2-HYDROXYIMINO-2-(2-AMINOTHIAZOL-4-YL) ACETIC ACID/HATA HATA ATHAA (Z)-2-(2-Amino-4-thiazolyl)-2-hydroxyiminoacetic acid (Z)-2-(2-aminothiazol-4-yl)-2-hydroxyiminoacetic Acid (HATA) 2-(2-Aminothiazole-4-yl)-2-hydroxyiminoaceticacid,97% (Z)-2-(2-Aminothiazole-4-yl)-2-hydroxyiminoacetic acid 2-(2-Aminothiazole-4-yl)-2-hydroxyiminoacetic acid ,98% 2-(2-aMino-1,3-thiazol-4-yl)-2-(N-hydroxyiMino)acetic acid Ceftazidime Impurity 21 4-Thiazoleacetic acid, 2-amino-α-(hydroxyimino)-, (αZ)- 4-Thiazoleacetic acid, 2-amino-a-(hydroxyimino)-, (aZ)- 4-Thiazylacetic acid (Z)-2-(2-Aminothiazol-4-yl)-2-(hydroxyimino)acetic acid - [A92221] 66338-96-3 C5H5N3O3S Cephalosporins