ChemicalBook >> CAS DataBase List >>5-Amino-1-(4-fluorophenyl)-1H-pyrazole-4-carboxylic acid
5-Amino-1-(4-fluorophenyl)-1H-pyrazole-4-carboxylic acid
- CAS No.
- 187949-90-2
- Chemical Name:
- 5-Amino-1-(4-fluorophenyl)-1H-pyrazole-4-carboxylic acid
- Synonyms
- BUTTPARK 23\09-45;RARECHEM AL BO 0714;SALOR-INT L252034-1EA;5-Amino-4-carboxy-1-(4-fluorophenyl)-1H-pyrazole;5-AMINO-1-(4-FLUOROPHENYL)-1H-PYRAZOLE-4-CARBOXYLIC;5-amino-1-(4-fluorophenyl)-4-pyrazolecarboxylic acid;5-Amino-1-(4-fluorophenyl)pyrazole-4-carboxylic Acid;5-Amino-1-(4-fluorophenyl)-1H-pyrazole-4-carboxylic acid;1H-Pyrazole-4-carboxylic acid, 5-amino-1-(4-fluorophenyl)-;5-Amino-4-carboxy-1-(4-fluorophenyl)-1H-pyrazole, 1-(5-Amino-4-carboxy-1H-pyrazol-1-yl)-4-fluorobenzene
- CBNumber:
- CB7737262
- Molecular Formula:
- C10H8FN3O2
- Molecular Weight:
- 221.19
- MDL Number:
- MFCD01569434
- MOL File:
- 187949-90-2.mol
- MSDS File:
- SDS
- TDS File:
- TDS
Last updated:2026-09-12 18:55:06
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H315-H319-H335 |
| Precautionary statements | P261-P305+P351+P338 |
| HS Code | 2933199090 |
5-Amino-1-(4-fluorophenyl)-1H-pyrazole-4-carboxylic acid price More Price(45)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | L252034 | 5-AMINO-1-(4-FLUOROPHENYL)-1H-PYRAZOLE-4-CARBOXYLIC ACID AldrichCPR | 187949-90-2 | 1 unit | $32.7 | 2026-04-30 | Buy |
| Sigma-Aldrich | L252034 | 5-AMINO-1-(4-FLUOROPHENYL)-1H-PYRAZOLE-4-CARBOXYLIC ACID AldrichCPR | 187949-90-2 | 250MG | $29.8 | 2024-03-01 | Buy |
| Usbiological | 261340 | 5-Amino-1-(4-fluorophenyl)-1H-pyrazole-4-carboxylic acid Asreported | 187949-90-2 | 250mg | $358 | 2026-06-03 | Buy |
| Usbiological | 261340 | 5-Amino-1-(4-fluorophenyl)-1H-pyrazole-4-carboxylic acid Asreported | 187949-90-2 | 500mg | $496 | 2026-06-03 | Buy |
| Usbiological | 261340 | 5-Amino-1-(4-fluorophenyl)-1H-pyrazole-4-carboxylic acid Asreported | 187949-90-2 | 1g | $847 | 2026-06-03 | Buy |
5-Amino-1-(4-fluorophenyl)-1H-pyrazole-4-carboxylic acid Chemical Properties,Uses,Production
Synthesis
138907-68-3
187949-90-2
mmol) in a solvent mixture of methanol (200 mL). The reaction mixture was heated to reflux for 17 h, followed by cooling to room temperature and filtration. The filtrate was acidified with 2 N HCl solution to pH=7. The precipitated solid was collected by filtration and dried under reduced pressure to afford the target compound 5-amino-1-(4-fluorophenyl)-1H-pyrazole-4-carboxylic acid as a light yellow solid (18.64 g, 95% yield), which was used in subsequent reactions without further purification.
References
[1] Patent: WO2008/53136, 2008, A1. Location in patent: Page/Page column 36
[2] Bioorganic and Medicinal Chemistry Letters, 2016, vol. 26, # 20, p. 5032 - 5038
[3] Journal of Medicinal Chemistry, 2006, vol. 49, # 5, p. 1562 - 1575
[4] Patent: WO2008/74814, 2008, A1. Location in patent: Page/Page column 56
[5] Patent: WO2008/777, 2008, A2. Location in patent: Page/Page column 58-59
Synthesis of 5-Amino-1-(4-fluorophenyl)-1H-pyrazole-4-carboxylic acid from Ethyl 5-amino-1-(4-fluorophenyl)pyrazole-4-carboxylate
5-Amino-1-(4-fluorophenyl)-1H-pyrazole-4-carboxylic acid Preparation Products And Raw materials
Raw materials
Preparation Products
5-Amino-1-(4-fluorophenyl)-1H-pyrazole-4-carboxylic acid Suppliers
Global( 77)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Chemsky（shanghai）International Co.,Ltd. | 021-50135380 | shchemsky@sina.com | China | 32273 | 50 |
| Shanghai Topbiochem Technology Co., Ltd | 021-58170097 | info@topbiochem.com | China | 9513 | 58 |
| Shanghai T&W Pharmaceutical Co., Ltd. | +86 21 61551611 | China | 9874 | 58 | |
| Shanghai Aladdin Bio-Chem Technology Co.,LTD | 400-6206333 13167063860 | anhua.mao@aladdin-e.com | China | 29985 | 65 |
| Shanghai Worldyang Chemical Co.,Ltd. | 021-56795766 | sales@worldyachem.com | China | 9475 | 58 |
| ShangHai AmK Pharmaceutical Technology Co., Ltd. | 微信 18019252918 18019252918 | sale@amkchem.com | China | 14982 | 55 |
| Shanghai Tombiopharma Chemical Co. Ltd. | 13391076197 | tombiopharma@163.com | China | 4986 | 55 |
| Cool Pharm, Ltd | 021-60455363 18019463053 | sales@coolpharm.com | China | 8455 | 58 |
| JW & Y Pharmlab Co., Ltd. | 021-64340559 | xinyu_shi@jwypharmlab.com.cn | China | 11999 | 58 |
| ShangHai Angti Biotechnology Co., Ltd. | 13764913901 | info@angtibio.com | China | 4975 | 55 |
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1of3
SALOR-INT L252034-1EA
RARECHEM AL BO 0714
BUTTPARK 23\09-45
5-amino-1-(4-fluorophenyl)-4-pyrazolecarboxylic acid
5-Amino-4-carboxy-1-(4-fluorophenyl)-1H-pyrazole
5-Amino-4-carboxy-1-(4-fluorophenyl)-1H-pyrazole, 1-(5-Amino-4-carboxy-1H-pyrazol-1-yl)-4-fluorobenzene
5-Amino-1-(4-fluorophenyl)pyrazole-4-carboxylic Acid
1H-Pyrazole-4-carboxylic acid, 5-amino-1-(4-fluorophenyl)-
5-AMINO-1-(4-FLUOROPHENYL)-1H-PYRAZOLE-4-CARBOXYLIC
5-Amino-1-(4-fluorophenyl)-1H-pyrazole-4-carboxylic acid
187949-90-2
