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Ethyl 5-amino-1-(4-fluorophenyl)pyrazole-4-carboxylate

CAS No.
138907-68-3
Chemical Name:
Ethyl 5-amino-1-(4-fluorophenyl)pyrazole-4-carboxylate
Synonyms
AKOS BBS-00007066;BUTTPARK 23\09-43;TIMTEC-BB SBB000884;SALOR-INT L251488-1EA;Ethyl 5-amino-1-(4-fluorophenyl)pyrazole-4-carboxylate;ETHYL 5-AMINO-1-(4-FLUOROPHENYL)-1H-PYRAZOLE-4-CARBOXYLATE;5-AMINO-1-(4-FLUOROPHENYL)-1H-PYRAZOLE-4-CARBOXYLIC ACID ETHYL ESTER;1H-Pyrazole-4-carboxylic acid, 5-amino-1-(4-fluorophenyl)-, ethyl ester;5-Amino-4-(ethoxycarbonyl)-1-(4-fluorophenyl)-1H-pyrazole, 1-[5-Amino-4-(ethoxycarbonyl)-1H-pyrazol-1-yl]-4-fluorobenzene
CBNumber:
CB8273208
Molecular Formula:
C12H12FN3O2
Molecular Weight:
249.24
MDL Number:
MFCD00173917
MOL File:
138907-68-3.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-09-12 18:55:37

Ethyl 5-amino-1-(4-fluorophenyl)pyrazole-4-carboxylate Properties

Melting point 153 °C
Boiling point 380.0±32.0 °C(Predicted)
Density 1.33±0.1 g/cm3(Predicted)
storage temp. 2-8°C, protect from light
pka 0.99±0.14(Predicted)
Appearance Off-white to light yellow Solid
CAS DataBase Reference 138907-68-3(CAS DataBase Reference)

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P305+P351+P338
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26-36/37/39
Hazard Note  Irritant
HS Code  2933199090

Ethyl 5-amino-1-(4-fluorophenyl)pyrazole-4-carboxylate price More Price(55)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Usbiological 275806 Ethyl 5-Amino-1-(4-fluorophenyl)pyrazole-4-carboxylate Asreported 138907-68-3 2g $353 2026-06-03 Buy
Usbiological 275806 Ethyl 5-Amino-1-(4-fluorophenyl)pyrazole-4-carboxylate Asreported 138907-68-3 5g $556 2026-06-03 Buy
Usbiological 275806 Ethyl 5-Amino-1-(4-fluorophenyl)pyrazole-4-carboxylate Asreported 138907-68-3 10g $769 2026-06-03 Buy
Usbiological 275806 Ethyl 5-Amino-1-(4-fluorophenyl)pyrazole-4-carboxylate Asreported 138907-68-3 25g $1067 2026-06-03 Buy
AstaTech 50175 ETHYL 5-AMINO-1-(4-FLUOROPHENYL)-1H-PYRAZOLE-4-CARBOXYLATE 95% 138907-68-3 1G $84 2026-04-30 Buy
Product number Packaging Price Buy
275806 2g $353 Buy
275806 5g $556 Buy
275806 10g $769 Buy
275806 25g $1067 Buy
50175 1G $84 Buy

Ethyl 5-amino-1-(4-fluorophenyl)pyrazole-4-carboxylate Chemical Properties, Uses, Production

Synthesis

Ethyl (ethoxymethylene)cyanoacetate

94-05-3

ETHYL 5-AMINO-1-(4-FLUOROPHENYL)PYRAZOLE-4-CARBOXYLATE

138907-68-3

The general procedure for the synthesis of ethyl 5-amino-1-(4-fluorophenyl)-1H-pyrazole-4-carboxylate from ethyl ethoxymethylcyanoacetate was as follows: 11.38 g (70.0 mmol) of 4-fluorophenylhydrazine hydrochloride, 11.84 g (70.0 mmol) of ethyl ethoxymethylcyanoacetate and 9.67 g (70.0 mmol) of potassium carbonate were dissolved in 100 mL of ethanol The reaction was heated to reflux overnight. After the reaction was completed, 300 mL of water was added to the reaction mixture and a precipitate was precipitated. The precipitate was collected by filtration and dried under vacuum to give 12.87 g of light yellow crystalline solid in 74% yield. The product was recrystallized from ethanol and the melting point was 151-152 °C. Elemental analysis results (C12H12FN3O2): calculated value C 57.82%, H 4.85%, N 16.86%; measured value C 57.82%, H 4.78%, N 16.79%.

References

[1] Patent: US5064851, 1991, A

Ethyl 5-amino-1-(4-fluorophenyl)pyrazole-4-carboxylate Suppliers

Global Suppliers ( 111)
Supplier Tel Email Country ProdList Advantage
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
Carbott PharmTech Inc. 0535-6385396 info@carbottpharm.com China 996 56
Wuhan Chemwish Technology Co., Ltd 86-027-67849912 sales@chemwish.com China 35884 56
Shanghai Sinch Parmaceuticals Tech. Co. Ltd. +86-21-54098501 sales@sinch.com.cn China 11592 64
Adamas Reagent, Ltd. 400-6009262 15618770481 yhx@titansci.com China 14098 59
Wuhan ariel chemical Co., LTD. 18986259541 18986259541 sales@3stc.com China 3828 58
Acorn PharmaTech Co., Ltd. 025-58395930 sales@acornpharma.com China 982 60
Chengdu HappySyn Pharmaceutical Technology Co., Ltd. 85114309 18982182443 yangli@happysyn.com China 2297 55
Thermo Fisher Scientific 800-810-5118 cnchemical@thermofisher.com China 17752 75
Candia Thamtech Company Limited 0371-86615086 18203638366 0371-86159066 13526786601 China 2011 60

View Latest Price from Ethyl 5-amino-1-(4-fluorophenyl)pyrazole-4-carboxylate manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
ETHYL 5-AMINO-1-(4-FLUOROPHENYL)PYRAZOLE-4-CARBOXYLATE pictures 2019-12-25 ETHYL 5-AMINO-1-(4-FLUOROPHENYL)PYRAZOLE-4-CARBOXYLATE
138907-68-3
$1.00 1KG 99% 200kg Career Henan Chemical Co
ETHYL 5-AMINO-1-(4-FLUOROPHENYL)-1H-PYRAZOLE-4-CARBOXYLATE BUTTPARK 23\09-43 5-AMINO-1-(4-FLUOROPHENYL)-1H-PYRAZOLE-4-CARBOXYLIC ACID ETHYL ESTER AKOS BBS-00007066 SALOR-INT L251488-1EA TIMTEC-BB SBB000884 5-Amino-4-(ethoxycarbonyl)-1-(4-fluorophenyl)-1H-pyrazole, 1-[5-Amino-4-(ethoxycarbonyl)-1H-pyrazol-1-yl]-4-fluorobenzene 1H-Pyrazole-4-carboxylic acid, 5-amino-1-(4-fluorophenyl)-, ethyl ester Ethyl 5-amino-1-(4-fluorophenyl)pyrazole-4-carboxylate 138907-68-3 C12H12FN3O2 ARYL AMINE