ChemicalBook >> CAS DataBase List >>6-chloro-1H-indazol-3-amine

6-chloro-1H-indazol-3-amine

6-chloro-1H-indazol-3-amine structure

CAS No.: 16889-21-7

Chemical Name:: 6-chloro-1H-indazol-3-amine

Synonyms: Zinc00154498;Einecs 240-925-9;6-chloro-1H-indazol-3-amine;3-Amino-6-chloro-1H-indazole;1H-Indazol-3-amine, 6-chloro-;6-chloro-1H-indoleazole-3-amine;6-Chloro-1H-Indazol-3-Amine (6-Chloro-1H-Indazol-3-Yl)Amine

CBNumber:: CB7932205

Molecular Formula:: C7H6ClN3

Molecular Weight:: 167.6

MDL Number:: MFCD00047207

MOL File:: 16889-21-7.mol

MSDS File:: SDS

Last updated:2026-05-28 02:56:32

Product description	Number	Pack Size	Price
6-Chloro-1H-indazol-3-amine	C-4160	10g	$262.4
6-Chloro-1H-indazol-3-amine	C-4160	25g	$570.25
6-Chloro-1H-indazol-3-amine	C-4160	50g	$991.5
6-Chloro-1H-indazol-3-amine	C-4160	100g	$1724
6-Chloro-1H-indazol-3-amine	C-4160	250g	$3745
More product size

Request For Quotation

6-chloro-1H-indazol-3-amine Properties

Boiling point	408.7±25.0 °C(Predicted)
Density	1.533±0.06 g/cm3(Predicted)
storage temp.	2-8°C(protect from light)
pka	13.72±0.40(Predicted)
Appearance	Off-white to pale purple Solid
InChI	InChI=1S/C7H6ClN3/c8-4-1-2-5-6(3-4)10-11-7(5)9/h1-3H,(H3,9,10,11)
InChIKey	BPTYMRSBTUERSW-UHFFFAOYSA-N
SMILES	N1C2=C(C=CC(Cl)=C2)C(N)=N1

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H302-H315-H319-H335
Precautionary statements	P261-P305+P351+P338

6-chloro-1H-indazol-3-amine price More Price(42)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Biosynth	C-4160	6-Chloro-1H-indazol-3-amine	16889-21-7	10g	$262.4	2026-06-04	Buy
Biosynth	C-4160	6-Chloro-1H-indazol-3-amine	16889-21-7	25g	$570.25	2026-06-04	Buy
Biosynth	C-4160	6-Chloro-1H-indazol-3-amine	16889-21-7	50g	$991.5	2026-06-04	Buy
Biosynth	C-4160	6-Chloro-1H-indazol-3-amine	16889-21-7	100g	$1724	2026-06-04	Buy
Biosynth	C-4160	6-Chloro-1H-indazol-3-amine	16889-21-7	250g	$3745	2026-06-04	Buy

Product number	Packaging	Price	Buy
C-4160	10g	$262.4	Buy
C-4160	25g	$570.25	Buy
C-4160	50g	$991.5	Buy
C-4160	100g	$1724	Buy
C-4160	250g	$3745	Buy

6-chloro-1H-indazol-3-amine Chemical Properties,Uses,Production

Uses

Starting from 6-chloro-1H-indazol-3-amine, the EDC/HOAt promoted coupling with the (S)-carboxylic acid derivative furnished (S)-1-(3-Amino-6-chloro-1H-indazol-1-yl)-2-methyl-3-phenoxypro-pan-1-one. This synthesis was performed to explore the structure-activity relationships (SAR) by substituting the indazole scaffold at the 6-position with a chlorine atom, facilitating the identification of novel CFTR potentiators.^[1]

References

[1] Liu, F., Kaplan, A. L., Levring, J., Einsiedel, J., Tiedt, S., Distler, K., Omattage, N. S., Kondratov, I. S., Moroz, Y. S., Pietz, H. L., Irwin, J. J., Gmeiner, P., Shoichet, B. K., & Chen, J. (2024). Structure-based discovery of CFTR potentiators and inhibitors. Cell, 42 1. https://doi.org/10.1016/j.cell.2024.04.046

6-chloro-1H-indazol-3-amine synthesis

Synthesis of 6-chloro-1H-indazol-3-amine from 4-Chloro-2-iodoaniline

6-chloro-1H-indazol-3-amine Preparation Products And Raw materials

Raw materials

Ammonium hydroxide N-Methyl-2-pyrrolidone Hydrazine hydrate Thionyl chloride 2,4-Dichlorobenzoic acid

4-Chloro-2-iodoaniline Benzonitrile, 2-broMo-4-hydrazinyl- 2-CHLORO-4-HYDRAZINYLBENZONITRILE(WX191485) 2-BROMO-4-CHLOROBENZONITRILE 2-Bromo-4-chlorobenzamide

4-Chloro-2-fluorobenzonitrile 2,4-Dichlorobenzonitrile

1of3

Preparation Products

6-chloro-1H-indazol-3-amine Suppliers

Global( 57)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Jinan Honest Pharm Co., Ltd	+8615318812076	zpy8217@163.com	China	286	58
Aladdin Scientific		tp@aladdinsci.com	United States	52923	58
Accela ChemBio Inc.	+1-858-6993322	info@accelachem.com	United States	21193	58
Alchem Pharmtech,Inc.	8485655694	sales@alchempharmtech.com	United States	63687	58
Guangzhou Yuheng Pharmaceutical Technology Co., Ltd	+8613580539051	joe@yuhengpharm.com	CHINA	21142	58
Zhengzhou Alfa Chemical Co.,Ltd	+8618530059196	sale04@alfachem.cn	China	9553	58
Career Henan Chemica Co	+86-0371-86658258 +8613203830695	laboratory@coreychem.com	China	30224	58
Dayang Chem (Hangzhou) Co.,Ltd.	+86-0571-88938639 +8617705817739	info@dycnchem.com	China	52704	58
Coresyn Pharmatech Co., Ltd.	+86-571-86626709 +86-18157142896	cbc@coresyn.com	China	9984	58
PT CHEM GROUP LIMITED	+86-85511178;	peter68@ptchemgroup.com	China	35425	58

Supplier	Advantage
Jinan Honest Pharm Co., Ltd	58
Aladdin Scientific	58
Accela ChemBio Inc.	58
Alchem Pharmtech,Inc.	58
Guangzhou Yuheng Pharmaceutical Technology Co., Ltd	58
Zhengzhou Alfa Chemical Co.,Ltd	58
Career Henan Chemica Co	58
Dayang Chem (Hangzhou) Co.,Ltd.	58
Coresyn Pharmatech Co., Ltd.	58
PT CHEM GROUP LIMITED	58

6-chloro-1H-indazol-3-amine Spectrum

6-chloro-1H-indazol-3-amine(16889-21-7)¹HNMR

16889-21-7(6-chloro-1H-indazol-3-amine)Related Search:

3-Amino-6-morpholin-4-ylpyridazine 5-CHLORO-1H-INDAZOL-3-YLAMINE (3-AMINO-5-NITROPHENYL)METHANOL 3-AMINO-4-CYANOPYRIDINE 3-AMINO-6-BROMOPYRAZINE-2-CARBONITRILE

3-aMino-5-broMo-4-chloropyridine 3-Amino-6-trifluoromethyl-pyridin-2-ol 3-AMINO-6-IODOPYRAZINE-2-CARBOXYLIC ACID METHYL ESTER 3-amino-6-chloropyrazine-2-carboxylic acid 3-AMINO-4-METHOXYPYRIDINE

3-AMINO-3-(4-CYANOPHENYL)PROPANOIC ACID 3-Amino-5-chloropyridin-2-ol HCl (3-aminopyrazin-2-yl)methanol 3-Amino-3-(4-methoxyphenyl)propionic acid 3-PYRIDINAMINE, 6-(1-METHYLETHYL)-

3-AMINO-5-HYDROXYBENZOIC ACID 2-CHLORO-5-IODO-PYRIDIN-3-YLAMINE 2-CHLORO-5-(TRIFLUOROMETHYL)-3-PYRIDINAMINE

1of4

6-Chloro-1H-Indazol-3-Amine (6-Chloro-1H-Indazol-3-Yl)Amine Zinc00154498 6-chloro-1H-indazol-3-amine Einecs 240-925-9 3-Amino-6-chloro-1H-indazole 1H-Indazol-3-amine, 6-chloro- 6-chloro-1H-indoleazole-3-amine 16889-21-7