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4-BROMO-7-FLUOROINDOLE

CAS No.
883500-66-1
Chemical Name:
4-BROMO-7-FLUOROINDOLE
Synonyms
4-BROMO-7-FLUORO-1H-INDOLE;4-BROMO-7-FLUOROINDOLE;1H-INDOLE,4-BROMO-7-FLUORO
CBNumber:
CB8120829
Molecular Formula:
C8H5BrFN
Molecular Weight:
214.03
MDL Number:
MFCD03095318
MOL File:
883500-66-1.mol
MSDS File:
SDS
Last updated:2026-05-28 03:16:50
Product description Number Pack Size Price
4-Bromo-7-fluoro-1H-indole 98% B47668 100mg $29
4-Bromo-7-fluoro-1H-indole 98% B47668 250mg $30
4-Bromo-7-fluoro-1H-indole 98% B47668 1g $120
4-Bromo-7-fluoro-1H-indole 98% B47668 5g $450
4-Bromo-7-fluoro-1H-indole 95% AA00473O 100mg $17
More product size

4-BROMO-7-FLUOROINDOLE Properties

Melting point 24-25℃
Boiling point 314.2±22.0 °C(Predicted)
Density 1.750±0.06 g/cm3(Predicted)
storage temp. under inert gas (nitrogen or Argon) at 2–8 °C
solubility Sparingly Soluble (0.28 g/L) (25°C)
pka 14.62±0.30(Predicted)
Appearance Colorless to light yellow Liquid
Sensitive Air Sensitive

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P280a-P304+P340-P305+P351+P338-P405-P501a
Hazard Codes  Xi
HazardClass  IRRITANT
HS Code  2933998090
NFPA 704
1
2 0

4-BROMO-7-FLUOROINDOLE price More Price(41)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Synthonix B47668 4-Bromo-7-fluoro-1H-indole 98% 883500-66-1 100mg $29 2026-05-06 Buy
Synthonix B47668 4-Bromo-7-fluoro-1H-indole 98% 883500-66-1 250mg $30 2026-05-06 Buy
Synthonix B47668 4-Bromo-7-fluoro-1H-indole 98% 883500-66-1 1g $120 2026-05-06 Buy
Synthonix B47668 4-Bromo-7-fluoro-1H-indole 98% 883500-66-1 5g $450 2026-05-06 Buy
aablocks AA00473O 4-Bromo-7-fluoro-1H-indole 95% 883500-66-1 100mg $17 2026-05-28 Buy
Product number Packaging Price Buy
B47668 100mg $29 Buy
B47668 250mg $30 Buy
B47668 1g $120 Buy
B47668 5g $450 Buy
AA00473O 100mg $17 Buy

4-BROMO-7-FLUOROINDOLE Chemical Properties,Uses,Production

Uses

It is a pharmaceutical intermediate.

Synthesis

4-Bromo-1-fluoro-2-nitrobenzene

364-73-8

Vinylmagnesium bromide

1826-67-1

4-BROMO-7-FLUOROINDOLE

883500-66-1

Vinylmagnesium bromide (300 mL of a 1.0 M THF solution, 300 mmol) was slowly added dropwise to a solution of 4-bromo-1-fluoro-2-nitrobenzene (22 g, 100 mmol) in anhydrous THF (700 mL) at -40 °C. The reaction temperature was maintained at -40 °C and after 1 h, the reaction was quenched with saturated aqueous NH4Cl solution. Subsequently, the reaction mixture was extracted with EtOAc (ethyl acetate). The organic layers were combined, dried with anhydrous Na2SO4, filtered and concentrated under reduced pressure to give the crude product. The crude product was purified by silica gel column chromatography, eluting with appropriate proportions of eluents to afford the target compound 4-bromo-7-fluoro-1H-indole (5 g, 23.3% yield). The structure of the product was confirmed by 1H NMR (CDCl3, 400 MHz): δ 6.56-6.58 (m, 1H), 6.72-6.79 (m, 1H), 7.06-7.17 (m, 1H), 7.20-7.24 (m, 1H), 8.45 (s, 1H).

References

[1] European Journal of Organic Chemistry, 2006, # 13, p. 2956 - 2969
[2] Patent: WO2013/117522, 2013, A1. Location in patent: Page/Page column 39
[3] Patent: US2015/18367, 2015, A1. Location in patent: Paragraph 0173; 0174
[4] Patent: EP2570125, 2013, A1. Location in patent: Paragraph 0151
[5] Patent: WO2013/37960, 2013, A1. Location in patent: Page/Page column 74

4-BROMO-7-FLUOROINDOLE Preparation Products And Raw materials

Global( 108)Suppliers
Supplier Tel Email Country ProdList Advantage
ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD
+86-15225627621 +86-13213167925 jiuyitime@fdachem.com China 16505 58
Capot Chemical Co.,Ltd.
+86-(0)57185586718 +86-13336195806 sales@capot.com China 29626 60
Alchem Pharmtech,Inc.
8485655694 sales@alchempharmtech.com United States 63645 58
career henan chemical co
+86-0371-86658258 factory@coreychem.com China 29780 58
KARMEL TECHNOLOGY (HK) CO.,LIMITED
+8618795957998 karmelhk@126.com CHINA 2886 58
Finetech Industry Limited
+86-27-8746-5837 +86-18627785180 info@finetechnology-ind.com China 9539 58
Hefei Hirisun Pharmatech Co., Ltd
+8615056975894 shawn@hirisunpharm.com CHINA 9897 58
CR Corporation Limited
fred.wen@crcorporation.cn China 8642 58
Suzhou Victorypharm Co.,Ltd.
+86-13916956214 sales@victory-pharm.com China 1298 58
Suzhou Laing Biotechnology Co.,Ltd
+86-13004516015 +86-18149392822 christina@laingbiotec.com China 777 58

View Lastest Price from 4-BROMO-7-FLUOROINDOLE manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
4-Bromo-7-fluoro-1H-indole pictures 2026-07-02 4-Bromo-7-fluoro-1H-indole
883500-66-1
$1.10-9.90 1KG 99% min 100kg ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD
4-BROMO-7-FLUOROINDOLE pictures 2019-12-20 4-BROMO-7-FLUOROINDOLE
883500-66-1
$1.00 1KG 99% Career Henan Chemical Co

4-BROMO-7-FLUOROINDOLE Spectrum

4-BROMO-7-FLUOROINDOLE 1H-INDOLE,4-BROMO-7-FLUORO 4-BROMO-7-FLUORO-1H-INDOLE 883500-66-1