2-METHYL-1,3-THIAZOLE-4-CARBONITRILE
- CAS No.
- 21917-76-0
- Chemical Name:
- 2-METHYL-1,3-THIAZOLE-4-CARBONITRILE
- Synonyms
- BUTTPARK 43\57-58;2-Methyl-4-cyanothiazole;4-Cyano-2-methyl-1,3-thiazole;2-methylthiazol-4-carbonitrile;2-METHYLTHIAZOLE-4-CARBONITRILE;2-Methyl-4-thiazolecarbonitrile;4-THIAZOLECARBONITRILE, 2-METHYL-;2-Methyl-1,3-thiazole-4-carbonitile;2-METHYL-1,3-THIAZOLE-4-CARBONITRILE
- CBNumber:
- CB8277039
- Molecular Formula:
- C5H4N2S
- Molecular Weight:
- 124.16
- MDL Number:
- MFCD00068103
- MOL File:
- 21917-76-0.mol
| Product description | Number | Pack Size | Price |
| 2-Methylthiazole-4-carbonitrile | M336543 | 1g | $240 |
| 2-Methyl-1,3-thiazole-4-carbonitrile | OR29666 | 1g | $86 |
| 2-Methyl-1,3-thiazole-4-carbonitrile | 7H70-1-6Q | 1g | $95 |
| 2-METHYL-1,3-THIAZOLE-4-CARBONITRILE 95.00% | CHM0021265 | 250MG | $632.8 |
| 2-METHYL-1,3-THIAZOLE-4-CARBONITRILE 95.00% | CHM0021265 | 1G | $676.46 |
| More product size | |||
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H332-H335 |
| Precautionary statements | P280-P305+P351+P338-P310 |
| Hazard Codes | Xi |
| Risk Statements | 20/21/22-41 |
| Safety Statements | 23-36/37/39-39-26 |
| RIDADR | 3276 |
| Hazard Note | Irritant |
| HS Code | 2934100090 |
2-METHYL-1,3-THIAZOLE-4-CARBONITRILE price More Price(18)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TRC | M336543 | 2-Methylthiazole-4-carbonitrile | 21917-76-0 | 1g | $240 | 2021-12-16 | Buy |
| Apolloscientific | OR29666 | 2-Methyl-1,3-thiazole-4-carbonitrile | 21917-76-0 | 1g | $86 | 2021-12-16 | Buy |
| SynQuest Laboratories | 7H70-1-6Q | 2-Methyl-1,3-thiazole-4-carbonitrile | 21917-76-0 | 1g | $95 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | CHM0021265 | 2-METHYL-1,3-THIAZOLE-4-CARBONITRILE 95.00% | 21917-76-0 | 250MG | $632.8 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | CHM0021265 | 2-METHYL-1,3-THIAZOLE-4-CARBONITRILE 95.00% | 21917-76-0 | 1G | $676.46 | 2021-12-16 | Buy |
2-METHYL-1,3-THIAZOLE-4-CARBONITRILE Chemical Properties,Uses,Production
Definition
ChEBI: 2-Methyl-1,3-thiazole-4-carbonitrile is a member of thiazoles.
Synthesis
31825-95-3
21917-76-0
The general procedure for synthesizing 2-methyl-1,3-thiazole-4-carbonitrile from 2-methylthiazole-4-carboxamide is as follows: general method: after completing the preparation of the amide intermediate, carry out the operation in Example A. According to the relationship between the boiling point of the amide intermediate and the reaction temperature TB, decide the state of the reaction vessel: if the boiling point of the amide intermediate at atmospheric pressure is equal to or lower than TB, close the reaction vessel; if the boiling point is higher than TB, keep the reaction vessel open. The stirring rate was maintained at 600 rpm, the reaction temperature was adjusted to TB and maintained at this temperature for TD hours until the reaction was nearly complete. Subsequently, the reaction vessel was sealed and connected to a vacuum pump, the vacuum in the reaction vessel was adjusted to 20-50 mbar (depending on the nature of the nitrile product) and the distillate was collected as the nitrile product. The yield was calculated and samples were taken for NMR spectroscopy and elemental analysis to characterize the obtained nitrile product. The specific reaction conditions and characterization results are detailed in Tables A-7, A-8, A-9, A-10, and A-11. The characterization results showed that the resulting nitrile product was of very high purity (over 99%). In some embodiments of the preparation of the nitrile product, 10 g of phosphorus pentoxide was selectively added as a catalyst at the initial stage of the reaction.
References
[1] Patent: CN104557357, 2018, B. Location in patent: Paragraph 0150; 0151; 0152; 0162
[2] ACS Medicinal Chemistry Letters, 2014, vol. 5, # 6, p. 628 - 633
[3] Bioorganic and Medicinal Chemistry Letters, 2002, vol. 12, # 8, p. 1203 - 1208
[4] Patent: WO2011/106414, 2011, A1. Location in patent: Page/Page column 83
[5] Journal of the Chemical Society [Section] C: Organic, 1969, p. 707 - 710
2-METHYL-1,3-THIAZOLE-4-CARBONITRILE Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 33024 | 60 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29850 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418671 +8618949823763 | sales@tnjchem.com | China | 34563 | 58 |
| Wuxi Rejoys chemical Technology Co., Ltd. | 0510-86103381 | sales@rejoyschem.com | CHINA | 976 | 58 |
| Dayang Chem (Hangzhou) Co.,Ltd. | +86-0571-88938639 +8617705817739 | info@dycnchem.com | China | 52846 | 58 |
| Golden Pharma Co., Limited | +undefined18958062155 | sales@zjgoldpharm.com | China | 5899 | 58 |
| PT CHEM GROUP LIMITED | +86-85511178; | peter68@ptchemgroup.com | China | 35425 | 58 |
| GIHI CHEMICALS CO.,LIMITED | +8618058761490 | info@gihichemicals.com | China | 49948 | 58 |
| Aceschem Inc. | +1-817863-6948 +1-（817）863-6948 | sales@aceschem.com | United States | 19632 | 58 |
View Lastest Price from 2-METHYL-1,3-THIAZOLE-4-CARBONITRILE manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2019-07-06 | 2-METHYL-1,3-THIAZOLE-4-CARBONITRILE
21917-76-0
|
US $8.00 / KG | 1KG | 99% | 10tons | Career Henan Chemical Co |
-
- 2-METHYL-1,3-THIAZOLE-4-CARBONITRILE
21917-76-0
- US $8.00 / KG
- 99%
- Career Henan Chemical Co
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