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(S,S)-(+)-N,N'-Bis(3,5-di-tert-butylsalicylidene)-1,2-cyclohexanediamino-cobalt(II)

(S,S)-(+)-N,N'-Bis(3,5-di-tert-butylsalicylidene)-1,2-cyclohexanediamino-cobalt(II) structure

CAS No.: 188264-84-8

Chemical Name:: (S,S)-(+)-N,N'-Bis(3,5-di-tert-butylsalicylidene)-1,2-cyclohexanediamino-cobalt(II)

Synonyms: S-SALEN-CO;(S,S)-Jacobsen cobalt (II) catalyst;(S,S)-(+)-N,N′-Bis(3,5-di-tert-butyL;(1S,2S)-(+)-1,2-Cyclohexanediamino-N,N'-bis(3,5-di-t-butylsa...;(S,S)-(+)-N,N'-Bis(3,5-di-tert-butylsalicylidene)-1,2-cyclohexane;-Bis(3,5-di-tert-butylsalicylidene)-1,2-cyclohexanediaminocobalt(II);(S,S)-(+)-N,N'-BIS(3,5-DI-TERT-BUTYLSALICYLIDENE)-1,2-CYCLOHEXANEDIAMINO-;(S,S)-N,N'-Bis(3,5-di-tert-butylsalicylidene)-1,2-cyclohexanediaminocobalt;(S,S)-N,N’-Bis(3,5-di-tert-butylsalicylidene)-1,2-cyclohexanediaminocobalt;(S,S)-N,N'-BIS(3,5-DI-T-BUTYLSALICYLIDEN E) -1,2-CYCLOHEXANEDIAMINOCOBALT(II)

CBNumber:: CB8331377

Molecular Formula:: C36H52CoN2O2

Molecular Weight:: 603.76

MDL Number:: MFCD01631278

MOL File:: 188264-84-8.mol

MSDS File:: SDS

TDS File:: TDS

Last updated:2026-09-12 18:55:38

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(S,S)-(+)-N,N'-Bis(3,5-di-tert-butylsalicylidene)-1,2-cyclohexanediamino-cobalt(II) Properties

Melting point	>350 °C(lit.)
storage temp.	Keep in dark place,Inert atmosphere,Room temperature
form	Powder
color	red-brown
InChIKey	ZFWPDJKMASHRPT-DKZUAMKGNA-L
SMILES	C(C1C=C(C(C)(C)C)C=C2C=N3[C@@]4([H])CCCC[C@]4([H])N4=CC5=CC(C(C)(C)C)=CC(C(C)(C)C)=C5[O-][Co+2]43[O-]C=12)(C)(C)C \|&1:12,18,r\|
UNSPSC Code	12352001
NACRES	NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS06
Signal word	Danger
Hazard statements	H302-H311-H332
Precautionary statements	P261-P271-P304+P340-P312-P264-P270-P301+P312-P330-P501-P280-P302+P352-P312-P322-P361-P363-P405-P501
PPE	dust mask type N95 (US), Eyeshields, Gloves
Hazard Codes	Xn
Risk Statements	20/21/22
Safety Statements	36/37/39-36/37
WGK Germany	3
Storage Class	11 - Combustible Solids

(S,S)-(+)-N,N'-Bis(3,5-di-tert-butylsalicylidene)-1,2-cyclohexanediamino-cobalt(II) price More Price(35)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	474606	(S,S)-(+)-N,N′-Bis(3,5-di-tert-butylsalicylidene)-1,2-cyclohexanediaminocobalt(II)	188264-84-8	1g	$57.6	2026-04-30	Buy
Sigma-Aldrich	474606	(S,S)-(+)-N,N′-Bis(3,5-di-tert-butylsalicylidene)-1,2-cyclohexanediaminocobalt(II)	188264-84-8	5g	$193	2026-04-30	Buy
Strem Chemicals	27-0526	(1S,2S)-(+)-1,2-Cyclohexanediamino-N,N'-bis(3,5-di-t-butylsalicylidene)cobalt(II)	188264-84-8	1g	$48	2026-04-30	Buy
Strem Chemicals	27-0526	(1S,2S)-(+)-1,2-Cyclohexanediamino-N,N'-bis(3,5-di-t-butylsalicylidene)cobalt(II)	188264-84-8	5g	$158	2026-04-30	Buy
Strem Chemicals	27-0526	(1S,2S)-(+)-1,2-Cyclohexanediamino-N,N'-bis(3,5-di-t-butylsalicylidene)cobalt(II)	188264-84-8	25g	$622	2026-04-30	Buy

Product number	Packaging	Price	Buy
474606	1g	$57.6	Buy
474606	5g	$193	Buy
27-0526	1g	$48	Buy
27-0526	5g	$158	Buy
27-0526	25g	$622	Buy

(S,S)-(+)-N,N'-Bis(3,5-di-tert-butylsalicylidene)-1,2-cyclohexanediamino-cobalt(II) Chemical Properties, Uses, Production

Reaction

Catalyst used in the kinetic resolution of racemic, terminal epoxides yielding a chiral diol and the unreacted enantiomer of the epoxide.
Precursor to a Co(III) catalyst for the kinetic resolution of terminal epoxides with alcohols.
Desymmetrization of meso-epoxides with carboxylic acids and fluoride.
Catalyst for asymmetric cyclopropanation of styrene.
Catalyst for copolymerization of CO2 and epoxides.
Enantioselective intramolecular openings of oxetanes.

Chemical Properties

red to red-brown powder

Uses

(S,S)-(+)-N,N''-Bis(3,5-di-tert-butylsalicylidene)-1,2-cyclohexanediaminocobalt(ii) i sused as a catalyst for the hydrolytic kinetic resolution of terminal epoxides and the enantioselective ring opening of meso epoxides.

Synthesis

71-48-7

(S,S)-(+)-N,N'-BIS(3,5-DI-TERT-BUTYLSALICYLIDENE)-1,2-CYCLOHEXANEDIAMINE

135616-36-3

(S,S)-(+)-N,N'-BIS(3,5-DI-TERT-BUTYLSALICYLIDENE)-1,2-CYCLOHEXANEDIAMINO-COBALT(II)

188264-84-8

The general procedure for the synthesis of (S,S)-N,N'-bis(3,5-di-tert-butylsalicylidene)-1,2-cyclohexanediamine cobalt(II) from cobalt acetate and 1,2-cyclohexylamine bis(3,5- butyl sulphate) is as follows: with reference to Example 1, (R,R)-N,N'-bis(3,5-di-tert-butylsalicylidene)-1,2-cyclohexanediamine (10.9 g. 20.0 mmol) was dissolved in dichloromethane (80 mL). The solution was slowly added to a methanol solution of cobalt tetrahydrate acetate (5.98 g, 24.0 mmol) (80 mL) and the reaction was stirred at room temperature for 15 min. A red solid gradually precipitated during the reaction. The reaction mixture was then continued to be stirred at 0 °C for 30 min to promote complete precipitation. The red solid was collected by filtration and the target product Co(L3) (11.6 g, red solid) was obtained after drying in 96% yield.

References

[1] Patent: US2006/173210, 2006, A1. Location in patent: Page/Page column 5

(S,S)-(+)-N,N'-Bis(3,5-di-tert-butylsalicylidene)-1,2-cyclohexanediamino-cobalt(II) Preparation Products And Raw materials

Raw materials

Phenol, 2,2'-[(1S,2S)-1,2-cyclohexanediylbis(nitrilomethylidyne)]bis[4,6-bis(1,1-dimethylethyl)- Cobalt acetate (S,S)-(+)-N,N'-Bis(3,5-di-tert-butylsalicylidene)-1,2-cyclohexanediamine

Preparation Products

(S,S)-(+)-N,N'-Bis(3,5-di-tert-butylsalicylidene)-1,2-cyclohexanediamino-cobalt(II) Suppliers

Global Suppliers ( 138)

Supplier	Tel	Email	Country	ProdList	Advantage
Shenzhen Feiming Science and Technology Co.,Ltd.	0755-85232577	sale@fmect.com	China	96	62
SHAOXING ZHIJUN PHARMACEUTICAL TECHNOLOGY CO.,LTD	0575-82126188 13858337171	service@zejunpharma.com	China	487	58
J & K SCIENTIFIC LTD.	18210857532 18210857532	jkinfo@jkchemical.com	China	96815	76
Meryer (Shanghai) Chemical Technology Co., Ltd.	4006356688 18621169109	market03@meryer.com	China	40202	62
ShangHai DEMO Chemical Co.,Ltd	400-021-7337 2355568890	sales@demochem.com	China	2569	57
Beijing HwrkChemical Technology Co., Ltd	89508211 18501085097	sales.bj@hwrkchemical.com	China	9407	55
Energy Chemical	400-0056266	sales8178@energy-chemical.com	China	44850	61
Beijing Ouhe Technology Co., Ltd	13552068683 13522913783	2355560935@qq.com	China	11777	60
Jia Xing Isenchem Co.,Ltd	0573-85285100 18627885956	isenchem@163.com	China	9389	66
Hunan Hui Bai Shi Biotechnology Co., Ltd.	0731-85526065 13308475853	ivy@hnhbsj.com	China	7236	62

Supplier	Advantage
Shenzhen Feiming Science and Technology Co.,Ltd.	62
SHAOXING ZHIJUN PHARMACEUTICAL TECHNOLOGY CO.,LTD	58
J & K SCIENTIFIC LTD.	76
Meryer (Shanghai) Chemical Technology Co., Ltd.	62
ShangHai DEMO Chemical Co.,Ltd	57
Beijing HwrkChemical Technology Co., Ltd	55
Energy Chemical	61
Beijing Ouhe Technology Co., Ltd	60
Jia Xing Isenchem Co.,Ltd	66
Hunan Hui Bai Shi Biotechnology Co., Ltd.	62

View Latest Price from (S,S)-(+)-N,N'-Bis(3,5-di-tert-butylsalicylidene)-1,2-cyclohexanediamino-cobalt(II) manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2026-09-18	(1S,2S)-(-)-N,N-Bis(3,5-di-t-butylsalicylidene)-1,2-cyclohexanediaminocobalt(II) 188264-84-8	$24.00-179.00	1g	0.98	25kg	Shanghai UCHEM Inc.
2025-12-24	(S,S)-(+)-N,N'-BIS(3,5-DI-TERT-BUTYLSALICYLIDENE)-1,2-CYCLOHEXANEDIAMINO-COBALT(II) 188264-84-8		1KG	98.0%	10	Shaanxi Dideu Medichem Co. Ltd
2021-07-02	(S,S)-(+)-N,N′-Bis(3,5-di-tert-butylsalicylidene)-1,2-cyclohexanediaminocobalt(II) 188264-84-8	$10.00-15.00	1KG	99%+ HPLC		Zhuozhou Wenxi import and Export Co., Ltd

(1S,2S)-(-)-N,N-Bis(3,5-di-t-butylsalicylidene)-1,2-cyclohexanediaminocobalt(II)
188264-84-8
$24.00-179.00
0.98
Shanghai UCHEM Inc.

(S,S)-(+)-N,N'-BIS(3,5-DI-TERT-BUTYLSALICYLIDENE)-1,2-CYCLOHEXANEDIAMINO-COBALT(II)
188264-84-8
$0.10
98.0%
Shaanxi Dideu Medichem Co. Ltd

(S,S)-(+)-N,N′-Bis(3,5-di-tert-butylsalicylidene)-1,2-cyclohexanediaminocobalt(II)
188264-84-8
$10.00-15.00
99%+ HPLC
Zhuozhou Wenxi import and Export Co., Ltd

188264-84-8 ((S,S)-(+)-N,N'-Bis(3,5-di-tert-butylsalicylidene)-1,2-cyclohexanediamino-cobalt(II)) Related Search:

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(1S,2S)-(+)-1,2-CYCLOHEXANEDIAMINO-N N'-BIS(3,5-DI-T-BUTYLSALICYLIDENE)COBALT(II) (1S,2S)-(+)-N,N'-BIS(3,5-DI-T-BUTYLSALICYDENE)-1,2-CYCLOHEXANEDIAMINOCOBALT(II) (1S,2S)-(+)-N,N-Bis(3,5-di-t-butylsalicylidene)-1,2-cyclohexanediaminocobalt(II) (S,S)-N,N'-BIS(3,5-DI-T-BUTYLSALICYLIDEN E) -1,2-CYCLOHEXANEDIAMINOCOBALT(II) (1S,2S)-(+)-1,2-Cyclohexanediamino-N,N'-bis(3,5-di-tert-butylsalicylidene)cobalt(II) (S,S)-(+)-N,N'-Bis(3,5-di-tert-butylsalicylidene)-1,2-cyclohexanediaminocobalt(II),98% (S,S)-(+)-N,N'-Bis(3,5-di-tert-butylsalicylidene)-1,2-cyclohexane (1S,2S)-N,N'-Bis(3,5-di-tert-butylsalicylidene)-1,2- cyclohexanediaminocobalt(II) -Bis(3,5-di-tert-butylsalicylidene)-1,2-cyclohexanediaminocobalt(II) 2,2'-{(1S,2S)-1,2-Cyclohexanediylbis[nitrilo(E)methylylidene]}bis [4,6-bis(2-methyl-2-propanyl)phenol] - cobalt (1:1) Cobalt,[[2,2'-[(1S,2S)-1,2-cyclohexanediylbis[(nitrilo-kN)methylidyne]]bis[4,6-bis(1,1-dimethylethyl)phenolato-kO]](2-)]-, (SP-4-2)- S-SALEN-CO (S,S)-(+)-N,N′-Bis(3,5-di-tert-butyL (S,S)-(+)-N,N'-BIS(3,5-DI-TERT-BUTYLSALICYLIDENE)-1,2-CYCLOHEXANEDIAMINO- Cobalt, [[2,2'-[(1S,2S)-1,2-cyclohexanediylbis[(nitrilo-κN)methylidyne]]bis[4,6-bis(1,1-dimethylethyl)phenolato-κO]](2-)]-, (SP-4-2)- (1S,2S)-(+)-1,2-Cyclohexanediamino-N,N'-bis(3,5-di-t-butylsa... TIANFU CHEM (S,S)-(+)-N,N'-BIS(3,5-DI-TERT-BUTYLSALICYLIDENE)-1,2-CYCLOHEXANEDIAMINO-COBALT(II) (S,S)-Jacobsen cobalt (II) catalyst (S,S)-N,N'-Bis(3,5-di-tert-butylsalicylidene)-1,2-cyclohexanediaminocobalt (1S,2S)-(-)-[1,2-Cyclohexanediamino-N,N'-bis(3,5-di-t-butylsalicylidene)]cobalt(II) (S,S)-(+)-N,N′-Bis(3,5-di-tert-butylsalicylidene)-1,2-cyclohexanediaminocobalt(II) (S,S)-N,N’-Bis(3,5-di-tert-butylsalicylidene)-1,2-cyclohexanediaminocobalt (S,S)-(+)-N,N'-Bis(3,5-di-tert-butylsalicylidene)-1,2-cyclohexanediamino-cobalt(II) 188264-84-8 Kinetic Resolution Asymmetric Synthesis Chiral Catalysts, Ligands, and Reagents Co Jacobsen Metal fine chemicals, specialty chemicals, intermediates, electronic chemical, organic synthesis Asymmetric Synthesis Chiral Catalysts, Ligands, and Reagents Kinetic ResolutionChiral Catalysts, Ligands, and Reagents Privileged Ligands and Complexes SALENs chem001