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5-Bromo-2-pyridinecarbonitrile

5-Bromo-2-pyridinecarbonitrile Structure
5-Bromo-2-pyridinecarbonitrile structure
CAS No.
97483-77-7
Chemical Name:
5-Bromo-2-pyridinecarbonitrile
Synonyms
5-BROMOPICOLINONITRILE;5-BROMO-2-CYANOPYRIDINE;2-CYANO-5-BROMOPYRIDINE;2-PYRIDI;Torezolid-12;IFLAB-BB F1926-0030;Tedizolid Impurity 40;Tedizolid Impurity 65;Tedizolid impurity587;2-CYANO-5-BROMOPYRIDIN
CBNumber:
CB2402716
Molecular Formula:
C6H3BrN2
Molecular Weight:
183.01
MDL Number:
MFCD00234144
MOL File:
97483-77-7.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-08-04 11:17:55
Product description Number Pack Size Price
5-Bromo-2-pyridinecarbonitrile 97% 641359 5g $47.8
5-Bromo-2-pyridinecarbonitrile 97% 641359 1g $20
5-Bromo-2-cyanopyridine >98.0%(GC) B3610 5g $39
5-Bromo-2-cyanopyridine >98.0%(GC) B3610 25g $122
3-Bromo-6-pyridinecarbonitrile (2-Cyano-5-Bromopyridine|5-Bromo-2-Cyanopyridine) B2866-50 2.5mg $319
More product size
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5-Bromo-2-pyridinecarbonitrile Properties

Melting point 128-132 °C (lit.)
Boiling point 100-110 °C/3 mmHg (lit.)
Density 1.72±0.1 g/cm3(Predicted)
storage temp. Inert atmosphere,Room Temperature
solubility Soluble in dichloromethane, ether, ethyl acetate and methanol
pka -2.68±0.10(Predicted)
form powder to crystal
color White to Light yellow to Light orange
BRN 5498624
InChI InChI=1S/C6H3BrN2/c7-5-1-2-6(3-8)9-4-5/h1-2,4H
InChIKey DMSHUVBQFSNBBL-UHFFFAOYSA-N
SMILES C1(C#N)=NC=C(Br)C=C1
CAS DataBase Reference 97483-77-7(CAS DataBase Reference)
UNSPSC Code 12352100
NACRES NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)  Corrosion (GHS05)Skull and Crossbones (GHS06)
GHS05,GHS06
Signal word  Danger
Hazard statements  H301-H315-H318-H335
Precautionary statements  P280-P301+P310+P330-P302+P352-P305+P351+P338+P310
target organs Respiratory system
PPE dust mask type N95 (US), Eyeshields, Faceshields, Gloves
Hazard Codes  Xn,T,Xi
Risk Statements  22-37/38-41-36/37/38-20/21/22-43
Safety Statements  26-36/37/39-36/37-9
RIDADR  UN 2811 6.1/PG 3
WGK Germany  3
Hazard Note  Harmful
HazardClass  6.1
PackingGroup  III
HS Code  29339900
Storage Class 6.1C - Combustible acute toxic Cat.3
toxic compounds or compounds which causing chronic effects
Hazard Classifications Acute Tox. 3 Oral
Eye Dam. 1
Skin Irrit. 2
STOT SE 3
Limited Quantities 5.0 kg (11 lbs) (solid)
Excepted Quantities Max Inner Pack (30g or 30ml) and Max Outer Pack (1Kg or 1L)
NFPA 704
1
2 0

5-Bromo-2-pyridinecarbonitrile price More Price(79)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 641359 5-Bromo-2-pyridinecarbonitrile 97% 97483-77-7 5g $47.8 2026-04-30 Buy
Sigma-Aldrich 641359 5-Bromo-2-pyridinecarbonitrile 97% 97483-77-7 1g $20 2023-06-20 Buy
TCI Chemical B3610 5-Bromo-2-cyanopyridine >98.0%(GC) 97483-77-7 5g $39 2026-04-30 Buy
TCI Chemical B3610 5-Bromo-2-cyanopyridine >98.0%(GC) 97483-77-7 25g $122 2026-04-30 Buy
Usbiological B2866-50 3-Bromo-6-pyridinecarbonitrile (2-Cyano-5-Bromopyridine|5-Bromo-2-Cyanopyridine) 97483-77-7 2.5mg $319 2026-06-03 Buy
Product number Packaging Price Buy
641359 5g $47.8 Buy
641359 1g $20 Buy
B3610 5g $39 Buy
B3610 25g $122 Buy
B2866-50 2.5mg $319 Buy

5-Bromo-2-pyridinecarbonitrile Chemical Properties,Uses,Production

Chemical Properties

Light yellow Cryst

Uses

5-Bromo-2-pyridinecarbonitrile can be used in the synthesis of aza-terphenyl diamidine analogs, which exhibits potent antiprotozoal activity. It can also be used in the synthesis of pyridine-diketopyrrolopyrrole(PyDPP), a building block for preparing low band-gap copolymers for use as electron donor in polymer solar cells.

Synthesis

A 3-step reaction was carried out to synthesize 5-bromo-2-cyanopyridine using 2-amino-5-bromopyridine as the starting material and the phosphorous trichloride/dichloromethane/pyridine (POCl3/CH2Cl2/Pyridine) system as the dehydrating reagent.

Chemical Properties

The intramolecular hyperconjugative interactions of the p to p* transitions from (C1—C2, C3—C4. C5—N6) p bonds in pyridine ring lead to strong delocalization. In particular, there is a little deviation in the energetic contributions from p (C1—C2 and C3—C4) bonds to p* [(C3—C4, C5—N6) and (C1—C2, C5—N6)] antibond transitions of (22.96, 17.04 kJ mol1 ) and (18.04, 24.81 kJ mol1 ), respectively, compared to other contributions in the ring. As well as the hyperconjugative interactions of the s / s* transitions occur from various bonds in our molecule; particularly, σ (C1—C11) and (C11—N12) having the bigger energetic contribution of their antibonding σ* (C11—N12) and (C1—C11) interactions at 8.28 and 8.68 kJ mol1 , respectively[1]. The most interaction energy, related to the resonance in the molecule, electron donating from the LP(2) N12 to the antibonding σ* (C1—C11) leads to moderate stabilization energy of 11.95 kJ mol1 is shown below.
5-Bromo-2-pyridinecarbonitrile

References

[1] Kandasamy, M. , and G. Velraj . "Ab initio/DFT electronic structure calculations, spectroscopic studies of 5-bromo-2-pyridinecarbonitrile – A comparative study." Solid State Sciences 14.8(2012):1071-1079.

5-Bromo-2-pyridinecarbonitrile synthesis

90145-48-5
97483-77-7
Synthesis of 5-Bromo-2-pyridinecarbonitrile from 5-BROMOPYRIDINE-2-CARBOXAMIDE 97%5-BROMOPICOLINAMIDE

5-Bromo-2-pyridinecarbonitrile Preparation Products And Raw materials

Raw materials

Preparation Products

2-Cyano-5-fluoropyridine 3-Bromo-2-cyanopyridine 5-BROMO-2-(2-METHYL-2H-TETRAZOL-5-YL)-PYRIDINE 5-BROMO-2-(1-METHYL-1H-TETRAZOL-5-YL)-PYRIDINE 5-Bromo-2-hydroxymethylpyridine
5-Bromo-2-pyridinecarboxylic Acid 5-((4-Methoxybenzyl)oxy)picolinonitrile 5-(4-bromophenyl)picolinonitrile 5-(4-FLUOROPHENYL)PYRIDINE-2-CARBONITRILE

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5-Bromo-2-pyridinecarbonitrile Suppliers

Global( 680)Suppliers
Supplier Tel Email Country ProdList Advantage
Shanghai Xinchem Co., Ltd.
+86-021-34123252 18049800532 xinchem@xinchem.com China 49 58
Shanghai Medfine Bio-pharmaceutical Co., Ltd
+86-86-13013810076 +86-13013810076 tina.lv@bio-medfine.com China 296 58
Hebei Chuanghai Biotechnology Co., Ltd 		+86-15350571055 Sibel@chuanghaibio.com China 8737 58
Capot Chemical Co.,Ltd. 		+86-（0）57185586718 +86-13336195806 sales@capot.com China 29626 60
Shanghai Bojing Chemical Co.,Ltd. 		+86-86-02137122233 +86-13795318958 bj1@bj-chem.com China 299 55
Henan Tianfu Chemical Co.,Ltd. 		+86-0371-55170693 +86-19937530512 info@tianfuchem.com China 21533 55
Shanghai Time Chemicals CO., Ltd. 		+86-021-57951555 +8618017249410 jack.li@time-chemicals.com China 1796 55
Nanjing ChemLin Chemical Industry Co., Ltd. 		025-83697070 product@chemlin.com.cn CHINA 3004 60
ATK CHEMICAL COMPANY LIMITED 		+undefined-21-51877795 ivan@atkchemical.com China 32997 60
Shanghai Zheyan Biotech Co., Ltd. 		18017610038 zheyansh@163.com CHINA 3618 58
Supplier Advantage
Shanghai Xinchem Co., Ltd.
58
Shanghai Medfine Bio-pharmaceutical Co., Ltd
58
Hebei Chuanghai Biotechnology Co., Ltd 		58
Capot Chemical Co.,Ltd. 		60
Shanghai Bojing Chemical Co.,Ltd. 		55
Henan Tianfu Chemical Co.,Ltd. 		55
Shanghai Time Chemicals CO., Ltd. 		55
Nanjing ChemLin Chemical Industry Co., Ltd. 		60
ATK CHEMICAL COMPANY LIMITED 		60
Shanghai Zheyan Biotech Co., Ltd. 		58

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View Lastest Price from 5-Bromo-2-pyridinecarbonitrile manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
5-Bromo-2-pyridinecarbonitrile pictures 2026-08-03 5-Bromo-2-pyridinecarbonitrile
97483-77-7
 1kg 98% 1000kgs Shaanxi Dideu New Materials Co. Ltd
5-Bromo-2-pyridinecarbonitrile pictures 2026-03-20 5-Bromo-2-pyridinecarbonitrile
97483-77-7
 $1.00 1KG 99% 10 mt Hebei Chuanghai Biotechnology Co., Ltd
5-Bromo-2-pyridinecarbonitrile pictures 2025-11-18 5-Bromo-2-pyridinecarbonitrile
97483-77-7
 $1.10 1g 99.00% 100 Tons Min Dideu Industries Group Limited

5-Bromo-2-pyridinecarbonitrile Spectrum

5-Bromo-2-pyridinecarbonitrile(97483-77-7)1HNMR

97483-77-7(5-Bromo-2-pyridinecarbonitrile)Related Search:

ETHYL 2-CYANOACRYLATE 3-Bromoanisole 4-Cyanopyridine 1-Hexadecylpyridinium bromide 3-Cyanopyridine
2-Hydroxypyridine 2-Cyanopyridine 2,6-Lutidine Methylene dithiocyanate Sodium cyanoborohydride
3-BROMO-2-PYRIDINECARBONITRILE 5-Bromo-2-nitropyridine (5R)-3-(4-BROMO-3-FLUOROPHENYL)-5-HYDROXYMETHYLOXAZOLIDIN-2-ONE 5-BROMO-4-METHYL-PYRIDINE-2-CARBONITRILE Torezolid
bis(((R)-3-(3-fluoro-4-(6-(2-methyl-2H-tetrazol-5-yl)pyridin-3-yl)phenyl)-2-oxooxazolidin-5-yl)methyl) hydrogen phosphate Tedizolid Impurity 36 (S)-(+)-Glycidyl butyrate

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Torezolid-12 5-Bromopicolinonitrile, 5-Bromo-2-cyanopyridine 5-Bromopyridine-2-carbonitrile 97% 5-BROMO-2-CYANOPYRIDINE99.0% 5-BroMo-2-pyridinecarbonitrile 97% 5 - broMine - 2 - cyanopyridine 2-PYRIDI Tedizolid Impurity 40 IFLAB-BB F1926-0030 5-BROMO-2-PYRIDINECARBONITRILE 5-BROMOPYRIDINE-2-CARBONITRILE 3-BROMO-6-PYRIDINECARBONITRILE 2-CYANO-5-BROMOPYRIDINE / 5-BROMO-2-CYANOPYRIDINE 2-PYRIDINECARBONITRILE, 5-BROMO- 2-CYANO-5-BROMOPYRIDIN 5-Bromopicolinonitrile, 5-Bromopyridine-2-carbonitrile 5-Bromo-2-pyridine nitrile 5-Bromo-2-cyanopyridine 97% 5-Bromo-2-cyanopyridine > 5-Bromo-2-cyanopyridine,>97% Tedizolid Impurity 65 5-Bromo-2-pyridinecarbonitrile ISO 9001：2015 REACH 5-Bromo-2-cyanopyridine-95% Tedizolid impurity587 2,7-DIBROMOPYRENE-4,5,9,14-TETRAONE 5-Bromo-2-cynopyridine 5-Bromopyridin-2-carbonitrile 5-bromo2-cyano pyrdine 2-Cyano-5-bromopyrdine Terazolamide impurity 13 2-cyno-5-Bromo pyridine Terdazolamide Impurity 13 2-CYANO-5-BROMOPYRIDINE 5-BROMO-2-CYANOPYRIDINE 5-BROMOPICOLINONITRILE 97483-77-7 97487-77-7 497483-77-7 97843-77-7 483-77-7 C6H3N2Br Pyridines Halogenated Heterocycles Heterocyclic Building Blocks Building Blocks Heterocyclic Building Blocks Cyano Organohalides Heterocyclic Compounds Pyridine Derivertives Pyridines, Pyrimidines, Purines and Pteredines Pyridines derivates Boron, Nitrile, Thio,& TM-Cpds Heterocycles blocks Bromides Carboxes Pyridines