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1-BOC-3-METHANESULFONYLOXYPYRROLIDINE

1-BOC-3-METHANESULFONYLOXYPYRROLIDINE structure

CAS No.: 141699-57-2

Chemical Name:: 1-BOC-3-METHANESULFONYLOXYPYRROLIDINE

Synonyms: 138883;(R)-3-(Methylsulphonyloxy)pyrrolidine;1-BOC-3-METHANESULFONYLOXYPYRROLIDINE;1-Boc-3-pyrrolidinyl Methanesulfonate;(3S)-N-Boc-3-[(methylsulphonyl)oxy]pyrrolidine;(R)-3-(Methylsulfonyloxy)pyrrolidine, N-BOC protected;(R)-3-(Methylsulphonyloxy)pyrrolidine, N-BOC protected;1-(tert-Butoxycarbonyl)pyrrolidin-3-yl methanesulfonate;2-(3-pyrrolidinyloxysulfonyl)acetic acid tert-butyl ester;(R)-3-(Methylsulphonyloxy)pyrrolidine, N-BOC protected 95+%

CBNumber:: CB8479581

Molecular Formula:: C10H19NO5S

Molecular Weight:: 265.33

MDL Number:: MFCD04116219

MOL File:: 141699-57-2.mol

Last updated:2025-07-24 18:13:46

Request For Quotation

1-BOC-3-METHANESULFONYLOXYPYRROLIDINE Properties

Boiling point	392.9±31.0 °C(Predicted)
Density	1.25±0.1 g/cm3(Predicted)
storage temp.	2-8°C
form	solid
pka	-3.65±0.40(Predicted)
UNSPSC Code	12352106

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS06
Signal word	Danger
Hazard statements	H301
Precautionary statements	P264-P270-P301+P310-P405-P501
Hazard Codes	Xi,T
Risk Statements	25
Safety Statements	45
WGK Germany	3
HazardClass	IRRITANT
HS Code	2933998090

1-BOC-3-METHANESULFONYLOXYPYRROLIDINE price More Price(35)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	ADE000053	(R)-3-Methanesulfonyloxy-pyrrolidine-1-carboxylic acid tert-butyl ester Aldrich	141699-57-2	1g	$216	2025-07-31	Buy
TRC	B809523	tert-Butyl3-((Methylsulfonyl)oxy)pyrrolidine-1-carboxylate	141699-57-2	100mg	$60	2021-12-16	Buy
TRC	B809523	tert-Butyl3-((Methylsulfonyl)oxy)pyrrolidine-1-carboxylate	141699-57-2	500mg	$155	2021-12-16	Buy
Matrix Scientific	018173	3-Methanesulfonyloxy-pyrrolidine-1-carboxylic acid tert-butyl ester	141699-57-2	1g	$63	2021-12-16	Buy
Biosynth Carbosynth	FB130822	tert-Butyl 3-[(methylsulfonyl)oxy]pyrrolidine-1-carboxylate	141699-57-2	1g	$255	2021-12-16	Buy

Product number	Packaging	Price	Buy
ADE000053	1g	$216	Buy
B809523	100mg	$60	Buy
B809523	500mg	$155	Buy
018173	1g	$63	Buy
FB130822	1g	$255	Buy

1-BOC-3-METHANESULFONYLOXYPYRROLIDINE Chemical Properties,Uses,Production

Synthesis

83220-73-9

124-63-0

141699-57-2

GENERAL STEPS: To a stirred solution of 1-tert-butoxycarbonyl-3-hydroxypyrrolidine (16 g, 85.4 mmol) and triethylamine (19 mL, 129 mmol) in 130 mL of dichloromethane was added slowly and dropwise to a solution of methanesulfonyl chloride (10 mL, 129 mmol) in 20 mL of dichloromethane at 0 °C. After the dropwise addition was completed, the reaction mixture was continued to be stirred at room temperature for 2.5 hours. Upon completion of the reaction, the reaction was quenched with saturated aqueous sodium bicarbonate and extracted with dichloromethane. The organic phases were combined, dried over anhydrous sodium sulfate and concentrated under reduced pressure to give tert-butyl 3-methanesulfonyloxypyrrolidine-1-carboxylate (22.7 g, 100% yield) as a yellow solid.

References

[1] Patent: WO2013/97773, 2013, A1. Location in patent: Paragraph 0150
[2] Patent: US2016/168156, 2016, A1. Location in patent: Paragraph 0494; 0495
[3] Patent: KR2016/103390, 2016, A. Location in patent: Paragraph 0099; 0102
[4] Patent: CN107474024, 2017, A. Location in patent: Paragraph 0385; 0389; 0390; 0391
[5] Patent: US2016/200730, 2016, A1. Location in patent: Paragraph 0278; 0279

1-BOC-3-METHANESULFONYLOXYPYRROLIDINE Preparation Products And Raw materials

Raw materials

1-Boc-(R)-(-)-3-Hydroxypyrrolidine Methanesulfonyl chloride N-Boc-3-pyrrolidinone Triethylamine Dichloromethane

Preparation Products

1-N-Boc-3-Cyanopyrrolidine

1-BOC-3-METHANESULFONYLOXYPYRROLIDINE Suppliers

Global( 75)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Capot Chemical Co.,Ltd.	+8613336195806	sales@capot.com	China	29734	60
Alchem Pharmtech,Inc.	8485655694	sales@alchempharmtech.com	United States	63687	58
CONIER CHEM AND PHARMA LIMITED	+8618523575427	sales@conier.com	China	49975	58
career henan chemical co	+86-0371-86658258 +8613203830695	factory@coreychem.com	China	29800	58
Zhengzhou Alfa Chemical Co.,Ltd	+8618530059196	sale04@alfachem.cn	China	12222	58
Dayang Chem (Hangzhou) Co.,Ltd.	+86-0571-88938639 +8617705817739	info@dycnchem.com	China	52846	58
Hangzhou Huarong Pharm Co., Ltd.	571-86758373 +8613588754946	sales@huarongpharm.com	CHINA	3148	58
Nextpeptide Inc	+86-0571-81612335 +8613336028439	sales@nextpeptide.com	China	19908	58
PT CHEM GROUP LIMITED	+86-85511178;	peter68@ptchemgroup.com	China	35425	58
GIHI CHEMICALS CO.,LIMITED	+8618058761490	info@gihichemicals.com	China	49977	58

Supplier	Advantage
Capot Chemical Co.,Ltd.	60
Alchem Pharmtech,Inc.	58
CONIER CHEM AND PHARMA LIMITED	58
career henan chemical co	58
Zhengzhou Alfa Chemical Co.,Ltd	58
Dayang Chem (Hangzhou) Co.,Ltd.	58
Hangzhou Huarong Pharm Co., Ltd.	58
Nextpeptide Inc	58
PT CHEM GROUP LIMITED	58
GIHI CHEMICALS CO.,LIMITED	58

View Lastest Price from 1-BOC-3-METHANESULFONYLOXYPYRROLIDINE manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2022-01-27	(R)-1-Boc-3-methanesulfonyloxypyrrolidine 141699-57-2	US $0.00 / KG	1KG	98.3%	100 tons	Honest Joy Holdings Limited
	2020-02-01	1-BOC-3-METHANESULFONYLOXYPYRROLIDINE 141699-57-2	US $1.00 / KG	1KG	98%	200kgs	Career Henan Chemical Co

(R)-1-Boc-3-methanesulfonyloxypyrrolidine
141699-57-2
US $0.00 / KG
98.3%
Honest Joy Holdings Limited

1-BOC-3-METHANESULFONYLOXYPYRROLIDINE
141699-57-2
US $1.00 / KG
98%
Career Henan Chemical Co

141699-57-2(1-BOC-3-METHANESULFONYLOXYPYRROLIDINE)Related Search:

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1-(tert-Butoxycarbonyl)pyrrolidin-3-yl methanesulfonate 1-BOC-3-METHANESULFONYLOXYPYRROLIDINE 3-METHANESULFONYLOXY-PYRROLIDINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER (R)-3-(Methylsulphonyloxy)pyrrolidine (R)-3-(Methylsulphonyloxy)pyrrolidine, N-BOC protected 138883 (R)-3-(Methylsulphonyloxy)pyrrolidine, N-BOC protected 95+% 2-(3-pyrrolidinyloxysulfonyl)acetic acid tert-butyl ester (R)-3-(Methylsulfonyloxy)pyrrolidine, N-BOC protected 1-Pyrrolidinecarboxylic acid, 3-[(methylsulfonyl)oxy]-, 1,1-dimethylethyl ester (3S)-N-Boc-3-[(methylsulphonyl)oxy]pyrrolidine 1-Boc-3-pyrrolidinyl Methanesulfonate 141699-57-2