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4-Chloropyridine-3-carboxaldehyde

4-Chloropyridine-3-carboxaldehyde structure

CAS No.: 114077-82-6

Chemical Name:: 4-Chloropyridine-3-carboxaldehyde

Synonyms: 4-Chloronicotinaldehyde;4-CHLORO-3-FORMYLPYRIDINE;4-chloro-3-pyridylazaldehyde;4-chloropyridin-3-carbaldehyde;4-chloropyridine-3-carbaldehyde;4-chloro-3-pyridinecarbaldehyde;4-chloro-3-pyridincarboxaldehyde;4-Chloro-3-pyridinecarboxaldehyde;4-CHLOROPYRIDINE-3-CARBOXALDEHYDE;4-Chhloropyridine-3-carboxaldehyde

CBNumber:: CB8687487

Molecular Formula:: C6H4ClNO

Molecular Weight:: 141.56

MDL Number:: MFCD04112523

MOL File:: 114077-82-6.mol

MSDS File:: SDS

TDS File:: TDS

Last updated:2026-05-28 05:03:46

Product description	Number	Pack Size	Price
4-Chloropyridine-3-carboxaldehyde Asreported	270323	500mg	$333
4-Chloropyridine-3-carboxaldehyde Asreported	270323	1g	$478
4-Chloropyridine-3-carboxaldehyde Asreported	270323	2g	$644
4-Chloropyridine-3-carboxaldehyde Asreported	270323	5g	$1093
4-Chloropyridine-3-carboxaldehyde Asreported	270323	10g	$1543
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4-Chloropyridine-3-carboxaldehyde Properties

Boiling point	228.8±20.0 °C(Predicted)
Density	1.332±0.06 g/cm3(Predicted)
storage temp.	Inert atmosphere,Store in freezer, under -20°C
pka	1.89±0.10(Predicted)
form	solid
color	Pale yellow
InChI	InChI=1S/C6H4ClNO/c7-6-1-2-8-3-5(6)4-9/h1-4H
InChIKey	DYRMBQRXOMOMNW-UHFFFAOYSA-N
SMILES	C1=NC=CC(Cl)=C1C=O

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H302-H317-H319
Precautionary statements	P280-P305+P351+P338
Hazard Codes	Xn
Risk Statements	22-36-43
Safety Statements	26-36/37
HS Code	2933399990

4-Chloropyridine-3-carboxaldehyde price More Price(65)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Usbiological	270323	4-Chloropyridine-3-carboxaldehyde Asreported	114077-82-6	500mg	$333	2026-06-03	Buy
Usbiological	270323	4-Chloropyridine-3-carboxaldehyde Asreported	114077-82-6	1g	$478	2026-06-03	Buy
Usbiological	270323	4-Chloropyridine-3-carboxaldehyde Asreported	114077-82-6	2g	$644	2026-06-03	Buy
Usbiological	270323	4-Chloropyridine-3-carboxaldehyde Asreported	114077-82-6	5g	$1093	2026-06-03	Buy
Usbiological	270323	4-Chloropyridine-3-carboxaldehyde Asreported	114077-82-6	10g	$1543	2026-06-03	Buy

Product number	Packaging	Price	Buy
270323	500mg	$333	Buy
270323	1g	$478	Buy
270323	2g	$644	Buy
270323	5g	$1093	Buy
270323	10g	$1543	Buy

4-Chloropyridine-3-carboxaldehyde Chemical Properties,Uses,Production

Chemical Properties

White to light yellow powder

Synthesis

626-61-9

68-12-2

114077-82-6

General procedure: a tetrahydrofuran solution (50 ml) of 4-chloropyridine (25.0 g, 0.22 mol) was slowly added dropwise to a solution of diisopropylammonium lithium prepared from a hexane solution of 1.6 M n-butyllithium (179 ml, 0.29 mol) with diisopropylamine (33.4 g, 0.33 mol) in tetrahydrofuran (300 ml) under the protection of argon gas, keeping the reaction temperature at -78°C. After dropwise addition, stirring was continued for 30 min. Subsequently, N,N-dimethylformamide (DMF, 19.3 g, 0.26 mol) was added and the reaction mixture was gradually warmed up to room temperature. After completion of the reaction, extraction was carried out with ethyl acetate (200 ml) and 5% aqueous ammonium chloride solution (300 ml). The organic layer was separated, dried with anhydrous magnesium sulfate and concentrated under reduced pressure to remove the solvent to give the crude product 4-chloro-3-pyridinecarboxaldehyde (27 g, 86% yield) as an oil. The product was characterized by 1H-NMR (200 MHz, CDCl3): δ 7.45 (1H, d, J = 5.0 Hz), 8.69 (1H, d, J = 5.0 Hz), 9.05 (1H, s), 10.51 (1H, s).

References

[1] Patent: EP1348706, 2003, A1. Location in patent: Page/Page column 37
[2] Patent: US2011/53975, 2011, A1. Location in patent: Page/Page column 60
[3] Journal of the American Chemical Society, 2013, vol. 135, # 40, p. 14916 - 14919
[4] Patent: WO2018/152329, 2018, A1. Location in patent: Page/Page column 44
[5] Patent: WO2004/41806, 2004, A2. Location in patent: Page 88-89

4-Chloropyridine-3-carboxaldehyde Preparation Products And Raw materials

Raw materials

Nitrogen Ethyl formate Sodium sulfate Sodium Diisopropylamine

Tetrahydrofuran Ethyl acetate Methanol 4-Chloropyridinium chloride n-Butyllithium

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Preparation Products

4-Chloro-3-difluoromethyl-pyridine

4-Chloropyridine-3-carboxaldehyde Suppliers

Global( 182)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Capot Chemical Co.,Ltd.	+86-（0）57185586718 +86-13336195806	sales@capot.com	China	29626	60
career henan chemical co	+86-0371-86658258	sales@coreychem.com	China	29766	58
CONIER CHEM AND PHARMA LIMITED		sales@conier.com	China	49906	58
Fuxin Pharmaceutical	+86-021-021-50872116	contact@fuxinpharm.com	China	9976	58
Dideu Industries Group Limited	+8617392712697	1022@dideu.com	China	29095	58
Finetech Industry Limited	+86-27-8746-5837 +86-18627785180	info@finetechnology-ind.com	China	9539	58
Dayang Chem (Hangzhou) Co.,Ltd.	+86-0571-88938639 17705817739	info@dycnchem.com	China	52693	58
GIHI CHEMICALS CO.,LIMITED	+86-571-86217390; +8618058761490	info@gihichemicals.com	China	49859	58
Protheragen-ING	+86-15618352007	info@protheragen-ing.com	United States	3867	58
HANGZHOU LEAP CHEM CO., LTD.	+86-571-87711850 +86-15355479329	market18@leapchem.com	China	43303	58

Supplier	Advantage
Capot Chemical Co.,Ltd.	60
career henan chemical co	58
CONIER CHEM AND PHARMA LIMITED	58
Fuxin Pharmaceutical	58
Dideu Industries Group Limited	58
Finetech Industry Limited	58
Dayang Chem (Hangzhou) Co.,Ltd.	58
GIHI CHEMICALS CO.,LIMITED	58
Protheragen-ING	58
HANGZHOU LEAP CHEM CO., LTD.	58

View Lastest Price from 4-Chloropyridine-3-carboxaldehyde manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2026-08-20	4-Chloropyridine-3-carboxaldehyde 114077-82-6	$1.10	1g	99.00%	100 Tons min	Dideu Industries Group Limited
2024-03-28	4-Chloropyridine-3-carboxaldehyde 114077-82-6		25kg	98%		PNP Biotech Co. Ltd
2019-07-06	4-Chloropyridine-3-carboxaldehyde 114077-82-6	$1.00	1kg	99%		Career Henan Chemical Co

4-Chloropyridine-3-carboxaldehyde
114077-82-6
$1.10
99.00%
Dideu Industries Group Limited

4-Chloropyridine-3-carboxaldehyde
114077-82-6
$0.00
98%
PNP Biotech Co. Ltd

4-Chloropyridine-3-carboxaldehyde
114077-82-6
$1.00
99%
Career Henan Chemical Co

4-Chloropyridine-3-carboxaldehyde Spectrum

4-Chloropyridine-3-carboxaldehyde(114077-82-6)¹HNMR

114077-82-6(4-Chloropyridine-3-carboxaldehyde)Related Search:

Chlorosulfonyl isocyanate Pentachloropyridine MCPA SODIUM N-Chlorosuccinimide 2-Chloro-5-chloromethylpyridine

3-Aminopyridine Clopidol 2-Chloro-3-cyanopyridine 3-Hydroxypyridine 4-Chloropyridinium chloride

4-CHLORO-1,3-DIMETHYLPYRAZOLO[3,4-B]PYRIDINE-5-CARBOXYLIC ACID 4-Chloronicotinic acid ETHYL 4-CHLORO-1,3-DIMETHYL-1H-PYRAZOLO[3,4-B]PYRIDINE-5-CARBOXYLATE 4-CHLORO-1,3-DIMETHYLPYRAZOLO[3,4-B]PYRIDINE-5-CARBONYL CHLORIDE 5-CHLORO-2-FORMYLPYRIDINE

5-Chloropyridine-3-carboxaldehyde 3-CHLOROISONICOTINALDEHYDE 2-CHLOROPYRIDINE-3-CARBOXALDEHYDE,2-Chloropyridine-3-carboxaldehyde, 2-Chloro-3-formylpyridine

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4-CHLOROPYRIDINE-3-CARBOXALDEHYDE 4-CHLORO-3-FORMYLPYRIDINE 3-Pyridinecarboxaldehyde,4-chloro-(9CI) 4-chloro-3-pyridincarboxaldehyde 4-Chloro-3-pyridinecarboxaldehyde 4-chloropyridin-3-carbaldehyde 4-Chloro-pyridine-3-carbaldehyde/4- Chloronicotinaldehyde 4-chloro-3-pyridinecarbaldehyde 4-chloropyridine-3-carbaldehyde 3-Pyridinecarboxaldehyde, 4-chloro- 4-Chloropyridine-3-carboxaldehyde≥ 98.5% (HPLC) 4-Chloropyridine-3-carboxaldehyde, 4-Chloro-3-formylpyridine 4-Chhloropyridine-3-carboxaldehyde 4-chloro-3-pyridylazaldehyde 4-Chloropyridine-3-carboxaldehyde ISO 9001：2015 REACH 4-Chloropyridine-3-carboxaldehyde CAS NO.114077-82-6 4-Chloronicotinaldehyde 114077-82-6 104077-82-6 Pyridines pyridine series PYRIDINE Building Blocks Heterocycle-Pyridine series