ChemicalBook >> CAS DataBase List >>3-Fluorophenylboronic acid
3-Fluorophenylboronic acid
- CAS No.
- 768-35-4
- Chemical Name:
- 3-Fluorophenylboronic acid
- Synonyms
- 3-FLUOROBENZENEBORONIC ACID;AKOS BRN-0105;3- Fluoroborate;RARECHEM AH PB 0217;3-Fluorophenylboroni;RSSYY(Iberdomide)-11;RSSYY(Iberdomide)-10;3-Fluorphenylboric acid;3-Fluorophenylboronic ac;3-FLUOROPHENYLBORNIC ACID
- CBNumber:
- CB9350601
- Molecular Formula:
- C6H6BFO2
- Molecular Weight:
- 139.92
- MDL Number:
- MFCD00236042
- MOL File:
- 768-35-4.mol
- MSDS File:
- SDS
- TDS File:
- TDS
Last updated:2026-05-28 05:30:12
| Melting point | 214-218 °C (lit.) |
|---|---|
| Boiling point | 271.4±42.0 °C(Predicted) |
| Density | 1.24±0.1 g/cm3(Predicted) |
| vapor pressure | 0Pa at 20℃ |
| storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
| solubility | soluble in Methanol |
| form | Crystalline Powder |
| pka | 7.50±0.10(Predicted) |
| color | White to off-white |
| Water Solubility | 27.1g/L at 20℃ |
| BRN | 3030632 |
| InChI | InChI=1S/C6H6BFO2/c8-6-3-1-2-5(4-6)7(9)10/h1-4,9-10H |
| InChIKey | KNXQDJCZSVHEIW-UHFFFAOYSA-N |
| SMILES | B(C1=CC=CC(F)=C1)(O)O |
| LogP | 2 at 23℃ |
| CAS DataBase Reference | 768-35-4(CAS DataBase Reference) |
| UNSPSC Code | 12352103 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS05,GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H314-H335 | |||||||||
| Precautionary statements | P260-P271-P280-P303+P361+P353-P304+P340+P310-P305+P351+P338 | |||||||||
| target organs | Respiratory system | |||||||||
| PPE | Eyeshields, Gloves, type N95 (US) | |||||||||
| Hazard Codes | Xn,Xi | |||||||||
| Risk Statements | 36/37/38-22 | |||||||||
| Safety Statements | 22-24/25-37/39-26-36 | |||||||||
| WGK Germany | 3 | |||||||||
| TSCA | No | |||||||||
| HazardClass | IRRITANT | |||||||||
| HS Code | 29163990 | |||||||||
| Storage Class | 8A - Combustible corrosive hazardous materials | |||||||||
| Hazard Classifications | Eye Dam. 1 Skin Corr. 1B STOT SE 3 |
|||||||||
| REACH Registrations | Active | |||||||||
| NFPA 704 |
|
3-Fluorophenylboronic acid price More Price(83)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 441643 | 3-Fluorophenylboronic acid ≥95.0% | 768-35-4 | 1g | $53.1 | 2026-04-30 | Buy |
| Sigma-Aldrich | 441643 | 3-Fluorophenylboronic acid ≥95.0% | 768-35-4 | 10g | $340 | 2026-04-30 | Buy |
| TCI Chemical | F0404 | 3-Fluorophenylboronic Acid (contains varying amounts of Anhydride) | 768-35-4 | 5g | $83 | 2026-04-30 | Buy |
| TCI Chemical | F0404 | 3-Fluorophenylboronic Acid (contains varying amounts of Anhydride) | 768-35-4 | 25g | $270 | 2026-04-30 | Buy |
| AstaTech | 58568 | 3-FLUOROPHENYL BORONIC ACID 98% | 768-35-4 | 5G | $23 | 2026-04-30 | Buy |
3-Fluorophenylboronic acid Chemical Properties, Uses, Production
Synthesis
The molar ratio of 3-fluorobromobenzene:magnesium:trimethyl borate is 1.0:1.1:1.5. The total mass of the solvent 2-methyltetrahydrofuran is 7 times the mass of 3-fluorobromobenzene.
The synthesis of 768-35-4 is synthesized in the following molar ratio: 1.0:1.1:1.5.
Add 2.6 g (0.11 mol) of magnesium filings and 1-2 grains of iodine to a 250 mL four-necked flask equipped with a reflux condenser and a constant-pressure dropping funnel. Add 30 g of 2-methyltetrahydrofuran. Under N2 protection at 40 °C, add 22.5 g of a 2-methyltetrahydrofuran solution containing 17.5 g (0.10 mol) of 3-fluorobromobenzene. After stirring to initiate the reaction, add the remaining 3-fluorobromobenzene solution. After the addition is complete, react at this temperature for 3 hours to prepare a 2-methyltetrahydrofuran solution of 3-fluorophenyl magnesium bromide. In a 500 mL four-necked flask, add 15.6 g (0.153 mol) of trimethyl borate and 90.0 g of 2-tetrahydrofuran. Cool to -20 °C under N2 protection. Add the above Grignard reagent solution. After the addition is complete, maintain the temperature for 3 hours. At this temperature, 100 mL of 8% hydrochloric acid was added, and the hydrolysis reaction was carried out for 2 hours. The organic phase was separated, and the aqueous layer was extracted with 2-methyltetrahydrofuran, then washed with saturated brine until neutral. The organic phases were combined, dried over anhydrous sodium sulfate, and the solvent was recovered under reduced pressure. The crude product was recrystallized from 1,2-dichloroethane to give 11.7 g of 3-fluorophenylboronic acid, white needle-like crystals, with a yield of 83.7%, an HPLC purity of 99.6%, and a melting point of 217.6–218.3 °C.Chemical Properties
white to light yellow crystal powder
Uses
suzuki reaction
Uses
Recently used to make novel liquid crystalline fluorobiphenylcyclohexenes and difluoroterphenyls by palladium-catalyzed cross-couplings also used in the synthesis of o-phenylphenols as potent leukotriene B4 receptor agonists.
Uses
Intermediates of Liquid Crystals
Flammability and Explosibility
Not classified
3-Fluorophenylboronic acid Preparation Products And Raw materials
Raw materials
Preparation Products
3'-Fluoro-biphenyl-4-ylamine hydrochloride
GNE-495
Methyl 3-fluorobenzoate
3-Chloro-6-(3-fluorophenyl)pyridazine
5-(3-Fluoro-phenyl)-furan-2-carbaldehyde
1of3
Global Suppliers ( 533)
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shandong INOV New Materials Co., Ltd. | 18369999171 | sales2@promisechemical.com | China | 85 | 58 |
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Meryer (Shanghai) Chemical Technology Co., Ltd. | 4006356688 18621169109 | market03@meryer.com | China | 40202 | 62 |
| INTATRADE GmbH | +49 3493/605464 | sales@intatrade.de | Germany | 3563 | 66 |
| Alfa Aesar | 400-6106006 | saleschina@alfa-asia.com | China | 30103 | 84 |
| TCI (Shanghai) Development Co., Ltd. | 021-67121386 | Sales-CN@TCIchemicals.com | China | 24512 | 81 |
| Energy Chemical | 400-0056266 | sales8178@energy-chemical.com | China | 44850 | 61 |
| Shijiazhuang Sdyano Fine Chemical Co., Ltd. | 0311-89250318 13582355795 | master@sjzsdyn.com | China | 2776 | 65 |
| Wuhan Chemwish Technology Co., Ltd | 86-027-67849912 | sales@chemwish.com | China | 35884 | 56 |
| Capot Chemical Co., Ltd | +86 (0) 571 85 58 67 18 | China | 18187 | 66 |
View Latest Price from 3-Fluorophenylboronic acid manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-09-02 | 3-Fluorophenylboronic acid
768-35-4
|
$1.20-34.00 | 1kg | 99% | Henan Fengda Chemical Co., Ltd | ||
 |
2025-06-27 | 3-Fluorophenylboronic acid
768-35-4
|
1KG | 99% | 500000kg | Hebei Chuanghai Biotechnology Co., Ltd | ||
 |
2025-06-20 | 3-Fluorophenylboronic acid
768-35-4
|
$3.00-20.00 | 1kg | 0.99 | 10 tons | Hebei Yanxi Chemical Co., Ltd. |
-
- 3-Fluorophenylboronic acid
768-35-4
- $1.20-34.00
- 99%
- Henan Fengda Chemical Co., Ltd
-
- 3-Fluorophenylboronic acid
768-35-4
- 99%
- Hebei Chuanghai Biotechnology Co., Ltd
-
- 3-Fluorophenylboronic acid
768-35-4
- $3.00-20.00
- 0.99
- Hebei Yanxi Chemical Co., Ltd.
768-35-4 (3-Fluorophenylboronic acid) Related Search:
3-FLUOROBENZENEBORONIC ACID
3-FLUORO PHENYLBORIC ACID
3-FLUOROPHENYLBORNIC ACID
3-FLUOROPHENYLBORONIC ACID
AKOS BRN-0105
RARECHEM AH PB 0217
M-FLUOROPHENYLBORONIC ACID
3-FLUOROBENZENEBORONIC ACID/3-FLUOROPHENYLBORONIC ACID
3-Fluorobenzeneboronicacid,97%
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3-Fluorophenylboronic Acid (contains varying amounts of Anhydride)
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3-Fluorophenylboronic acid,3-Fluorobenzeneboronic acid
3-Fluorophenylboroni
Boric acid between fluorobenzene
3-Fluorophenylboronic acid ,98%
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3-Fluorophenylboronic ac
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3-FLUOROPHENYLBORONIC ACID FOR SYNTHESIS
(3-Fluorophenyl-1-yl)boronic acid
m-fluoro-Benzeneboronic acid
3-Fluorophenylboronic acid >=95.0%
3-Fluorophenylboronic acid, 98%, for synthesis
3- Fluoroborate
3-Fluorophenylboronic Acid extrapure, 98%
RSSYY(Iberdomide)-11
RSSYY(Iberdomide)-10
3-Fluorphenylboric acid
(3-Fluorophenyl)boronic acid - [F3360]
768-35-4
786-35-4
135412-35-8
BORONIC ACID
Organometallic Reagents
B (Classes of Boron Compounds)
Boronic Acids
Boronic Acids and Derivatives
Aryl
Boronate Ester
Potassium Trifluoroborate
Substituted Boronic Acids
Boron, Nitrile, Thio,& TM-Cpds
B (Classes of Boron Compounds)
Boronic Acids
CHIRAL CHEMICALS
Boronic Acids & Esters
Phenyls & Phenyl-Het
blocks
BoronicAcids
FluoroCompounds
Boronic Acid series
Fluoro-Aromatics
Boronic Acids & Esters
Phenyls & Phenyl-Het
Fluorobenzene
