Isoprocarb
- CAS No.
- 2631-40-5
- Chemical Name:
- Isoprocarb
- Synonyms
- MIPC;2-Isopropylphenyl methylcarbamate;Phenol, 2-(1-methylethyl)-, methylcarbamate;mipc (jmaf);ppc3;Ppc 3;Hytox;Mipsin;Oms 32;oms-32
- CBNumber:
- CB9380741
- Molecular Formula:
- C11H15NO2
- Molecular Weight:
- 193.24
- MDL Number:
- MFCD00053078
- MOL File:
- 2631-40-5.mol
- TDS File:
- TDS
| Melting point | 92.4°C |
|---|---|
| Boiling point | 329.46°C (rough estimate) |
| Density | 1.0945 (rough estimate) |
| refractive index | 1.5080 (estimate) |
| Flash point | -18 °C |
| storage temp. | Sealed in dry,2-8°C |
| solubility | Chloroform (Slightly), Methanol (Slightly) |
| form | Crystalline |
| pka | 12.22±0.46(Predicted) |
| color | White to off-white |
| BRN | 1875020 |
| Henry's Law Constant | 7.4×102 mol/(m3Pa) at 25℃, Duchowicz et al. (2020) |
| Major Application |
agriculture environmental |
| InChI | InChI=1S/C11H15NO2/c1-8(2)9-6-4-5-7-10(9)14-11(13)12-3/h4-8H,1-3H3,(H,12,13) |
| InChIKey | QBSJMKIUCUGGNG-UHFFFAOYSA-N |
| SMILES | C1(OC(=O)NC)=CC=CC=C1C(C)C |
| CAS DataBase Reference | 2631-40-5(CAS DataBase Reference) |
| EWG's Food Scores | 1 |
| FDA UNII | 714I55QH9K |
| NIST Chemistry Reference | 2-(1-Methylethyl)phenyl methylcarbamate(2631-40-5) |
| EPA Substance Registry System | Isoprocarb (2631-40-5) |
| UNSPSC Code | 41116107 |
| NACRES | NA.24 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS07,GHS09 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H410 |
| Precautionary statements | P273-P301+P312+P330 |
| PPE | dust mask type N95 (US), Eyeshields, Faceshields, Gloves |
| Hazard Codes | Xn,N,F |
| Risk Statements | 22-50/53-67-65-38-11-20 |
| Safety Statements | 60-61-62-33-16-9-25 |
| RIDADR | UN 3077 9/PG 3 |
| WGK Germany | 3 |
| RTECS | FB7880000 |
| TSCA | TSCA listed |
| HS Code | 29224999 |
| Storage Class | 11 - Combustible Solids |
| Hazard Classifications | Acute Tox. 4 Oral Aquatic Acute 1 Aquatic Chronic 1 |
Isoprocarb price More Price(21)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 45541 | Isoprocarb PESTANAL | 2631-40-5 | 50mg | $134 | 2026-04-30 | Buy |
| Sigma-Aldrich | 41342 | Isoprocarb certified reference material, TraceCERT®, Manufactured by: Sigma-Aldrich Production GmbH, Switzerland | 2631-40-5 | 50 mg | $149 | 2026-04-30 | Buy |
| TRC | TRC-I822400-1G | Isoprocarb | 2631-40-5 | 1g | $198 | 2026-06-03 | Buy |
| TRC | TRC-I822400-10G | Isoprocarb | 2631-40-5 | 10g | $1464 | 2026-06-03 | Buy |
| Usbiological | 015077 | Isoprocarb | 2631-40-5 | 1g | $403 | 2026-06-03 | Buy |
Isoprocarb Chemical Properties,Uses,Production
Description
Isoprocarb, o-cumenyl methylcarbamate (IUPAC), consists of colorless crystals, which are sparingly soluble in water and are readily soluble in acetone and methanol. Isoprocarb is produced by reaction of 2-isopropylphenol with methylisocyanate. Isoprocarb is used for control of rice, cacao, sugarcane, and vegetable pests.
Chemical Properties
Isoprocarb is a carbamate insecticide. It is a colourless crystalline substance, sparingly soluble in water (0.265g/l) and readily soluble in acetone(400g/l) and methanol (125g/l). It is hydrolysed in alkaline media.
The insecticide,with contact and stomach action, effectively controls leafhoppers,plant hoppers and aphids on a variety of crops like rice, cocoa, sugarcane and vegetables. Its residual activity gives effective pest control. It acts by inhibiting cholinesterase.
Uses
Isoprocarb is a non-systematic carbamate insecticide. Isoprocarb functions by reversibly inactivating the enzyme acetylcholinesterase in insects.
Definition
ChEBI: Isoprocarb is a carbamate ester. It has a role as an EC 3.1.1.7 (acetylcholinesterase) inhibitor, a carbamate insecticide and an agrochemical. It is functionally related to a methylcarbamic acid and a 2-isopropylphenol.
Production Methods
Isoprocarb is commercially produced via a concise 2–3 step synthesis that begins with the preparation of 2-isopropylphenyl chloroformate by reacting 2-isopropylphenol with phosgene in toluene in the presence of a catalytic amount of DMF. The key carbamoylation occurs through nucleophilic addition of methylamine to the chloroformate intermediate under controlled pH to form the methylcarbamate linkage, minimizing hydrolysis. Final purification via vacuum distillation or crystallisation from hexane yields isoprocarb.
Mechanism of action
Contact and stomach action. Acetylcholinesterase (AChE) inhibitor.
Safety Profile
Poison by ingestion, intravenous, and intraperitoneal routes. Moderately toxic by skin contact. When heated to decomposition it emits toxic fumes of NOx. See also CARBAMATES. Used for controlling leafhoppers, planthoppers, and bugs in rice and cacao.
Toxicology
The insecticide isoprocarb is a Class II toxin (moderately hazardous), with the acute oral LD50 among rats being 403-485mg/kg, while the percutaneous LD50 among male rats and mice is>500mg. It is a PAN Bad Actor chemical, since it is a cholinesterase inhibitor. Symptoms of poisoning with this insecticide include muscle weakness,dizziness,salivation,nausea,vomiting,sweating,headache,effects on the CNS and depression. PPE such as splash-resistant safety goggles and chemicalresistant clothing, gloves and masks are advised.
Pesticide Type
Insecticide
Isoprocarb Preparation Products And Raw materials
Raw materials
1of4
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Jiangsu Jialong Chemical Co., Ltd | -- | tjchun@jialongchem.com | China | 54 | 38 |
| Hebei Dueling International Trade Co. LTD | 18032116176 | 399549586@qq.com | China | 1178 | 58 |
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Beijing HwrkChemical Technology Co., Ltd | 89508211 18501085097 | sales.bj@hwrkchemical.com | China | 9407 | 55 |
| Chemsky（shanghai）International Co.,Ltd. | 021-50135380 | shchemsky@sina.com | China | 32273 | 50 |
| Sichuan Kulinan Technology Co., Ltd | 400-1166-196 18981987031 | cdhxsj@163.com | China | 11674 | 57 |
| Chengdu Ai Keda Chemical Technology Co., Ltd. | 4008-755-333 18080918076 | 800078821@qq.com | China | 9706 | 55 |
| 9ding chemical ( Shanghai) Limited | 4009209199 | sales@9dingchem.com | China | 22497 | 55 |
| Shanghai Aladdin Bio-Chem Technology Co.,LTD | 400-6206333 13167063860 | anhua.mao@aladdin-e.com | China | 29985 | 65 |
| Nanjing Sunlida Biological Technology Co., Ltd. | 025-57798810 18652991625 | sales@sunlidabio.com | China | 3223 | 55 |
View Lastest Price from Isoprocarb manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-07-14 | isoprocarb
2631-40-5
|
1kg | 99 | 20tons | Qingdao Trust Agri Chemical Co.,Ltd | ||
 |
2026-03-20 | Isoprocarb
2631-40-5
|
$10.00 | 1KG | 99% | 10 mt | Hebei Chuanghai Biotechnology Co., Ltd | |
 |
2021-08-14 | Isoprocarb
2631-40-5
|
$10.00 | 1KG | 99 | 1000 Kilogram/Kilograms per Month | Shijiazhuang tongyang Import and Export Co., LTD |
-
- isoprocarb
2631-40-5
- $0.00
- 99
- Qingdao Trust Agri Chemical Co.,Ltd
-
- Isoprocarb
2631-40-5
- $10.00
- 99%
- Hebei Chuanghai Biotechnology Co., Ltd
-
- Isoprocarb
2631-40-5
- $10.00
- 99
- Shijiazhuang tongyang Import and Export Co., LTD
