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FMOC-b-Ala-OH

FMOC-b-Ala-OH Structure
FMOC-b-Ala-OH structure
CAS No.
35737-10-1
Chemical Name:
FMOC-b-Ala-OH
Synonyms
FMoc-β-Ala-OH;FMOC-BETA-ALA-OH;3-((((9H-Fluoren-9-yl)Methoxy)carbonyl)aMino)propanoic acid;FMoc-Beta-Ala;FMoc-B-Ala;Fmoc-β-alanine;N-Fmoc-β-alanine;-Ala-OH;-Ala-OPfp;FMOC-b-AL
CBNumber:
CB9395385
Molecular Formula:
C18H17NO4
Molecular Weight:
311.34
MDL Number:
MFCD00063328
MOL File:
35737-10-1.mol
MSDS File:
SDS
Last updated:2026-01-13 11:27:10
Product description Number Pack Size Price
FMOC-ß-ALA-OH Novabiochem? 8.52024 5G $54.6
FMOC-ß-ALA-OH Novabiochem? 8.52024 25g $207
FMOC-ß-ALA-OH Novabiochem® 8.52024 100 g $793
FMOC-ß-ALA-OH Novabiochem® 8.52024 100 g $793
FMOC-ß-ALA-OH Novabiochem® 8.52024 500 g $2270
More product size
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FMOC-b-Ala-OH Properties

Melting point 142-147 °C
Boiling point 451.38°C (rough estimate)
Density 1.2626 (rough estimate)
refractive index 1.5100 (estimate)
storage temp. 2-8°C
solubility Soluble in water or 1% acetic acid
pka 4.41±0.10(Predicted)
form powder to crystal
color White to Almost white
Water Solubility Soluble in water and 1% acetic acid.
BRN 2302327
Major Application peptide synthesis
InChI 1S/C18H17NO4/c20-17(21)9-10-19-18(22)23-11-16-14-7-3-1-5-12(14)13-6-2-4-8-15(13)16/h1-8,16H,9-11H2,(H,19,22)(H,20,21)
InChIKey LINBWYYLPWJQHE-UHFFFAOYSA-N
SMILES OC(=O)CCNC(=O)OCC1c2ccccc2-c3ccccc13
CAS DataBase Reference 35737-10-1(CAS DataBase Reference)
FDA UNII 7G6VG65WAL
UNSPSC Code 12352209
NACRES NA.26

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H319-H335-H315
Precautionary statements  P264-P280-P302+P352-P321-P332+P313-P362-P264-P280-P305+P351+P338-P337+P313P
PPE Eyeshields, Gloves, type N95 (US)
Safety Statements  22-24/25
WGK Germany  3
HS Code  2924 29 70
HazardClass  IRRITANT
Storage Class 11 - Combustible Solids
NFPA 704
1
0 0

FMOC-b-Ala-OH price More Price(47)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 8.52024 FMOC-ß-ALA-OH Novabiochem? 35737-10-1 5G $54.6 2025-07-31 Buy
Sigma-Aldrich 8.52024 FMOC-ß-ALA-OH Novabiochem? 35737-10-1 25g $207 2025-07-31 Buy
Sigma-Aldrich 8.52024 FMOC-ß-ALA-OH Novabiochem® 35737-10-1 100 g $793 2025-07-31 Buy
Sigma-Aldrich 8.52024 FMOC-ß-ALA-OH Novabiochem® 35737-10-1 100 g $793 2025-07-31 Buy
Sigma-Aldrich 8.52024 FMOC-ß-ALA-OH Novabiochem® 35737-10-1 500 g $2270 2025-07-31 Buy
Product number Packaging Price Buy
8.52024 5G $54.6 Buy
8.52024 25g $207 Buy
8.52024 100 g $793 Buy
8.52024 100 g $793 Buy
8.52024 500 g $2270 Buy

FMOC-b-Ala-OH Chemical Properties,Uses,Production

Chemical Properties

white to light yellow crystal powde

Uses

It is an important raw material and intermediate used in organic synthesis, pharmaceuticals, agrochemicals and dyestuffs.

reaction suitability

reaction type: Fmoc solid-phase peptide synthesis

Synthesis

9-Fluorenylmethyl chloroformate

28920-43-6

β-Alanine

107-95-9

FMOC-b-Ala-OH

35737-10-1

Under stirring conditions, β-alanine (β-Ala, 0.5 g, 6.61 mmol) was dissolved in 10% aqueous Na2CO3 solution (12 ml) in a 50 ml flask. The flask was cooled in an ice bath followed by slow dropwise addition of Fmoc-Cl (1.45 g, 5.61 mmol) in dioxane (10 ml) solution. The reaction mixture was stirred continuously for 4 hours at room temperature. After completion of the reaction, the aqueous phase layer was separated by adding water (80 ml) for dilution and washed three times (75 ml each) with ether. The aqueous phase layer was acidified to pH=2 with 2N HCl aqueous solution and subsequently extracted with ethyl acetate three times (75 ml each). The organic phase layers were combined and concentrated to give 1.50 g of crude product. The crude product was recrystallized by a solvent mixture of ethyl acetate and hexane (1:2, 30 ml, v/v) and filtered under reduced pressure to obtain a white solid, Fmoc-β-Ala. yield: 1.41 g (81%). NMR (CDCl3) δ 2.6 (t, 2H, NHCH2CH2COOH), 3.47 (d, 2H, J = 7.0 Hz, NHCH2CH2COOH), 4.19 (t, 1H, J = 6.0 Hz, Fmoc-CH), 4.39 (d, 2H, J = 7.0 Hz, Fmoc-CH2), 7.29 (t, 2H , J = 7.3 Hz, Ar-H), 7.38 (t, 2H, J = 7.3 Hz, Ar-H), 7.56 (d, 2H, J = 7.0 Hz, Ar-H), 7.74 (d, 2H, J = 7.5 Hz, Ar-H).

References

[1] Tetrahedron, 1991, vol. 47, # 14-15, p. 2389 - 2400
[2] Patent: US2009/131681, 2009, A1. Location in patent: Page/Page column 3
[3] Journal of Organic Chemistry, 1972, vol. 37, # 22, p. 3404 - 3409
[4] Bioorganic Chemistry, 1996, vol. 24, # 1, p. 50 - 58
[5] Russian Journal of General Chemistry, 2010, vol. 80, # 12, p. 2572 - 2589

FMOC-b-Ala-OH synthesis

28920-43-6
107-95-9
35737-10-1
Synthesis of FMOC-b-Ala-OH from 9-Fluorenylmethyl chloroformate and β-Alanine

FMOC-b-Ala-OH Preparation Products And Raw materials

Raw materials

Fmoc-Gly-OH 9-Fluorenylmethyl chloroformate β-Alanine Hydrochloric acid 1,4-Dioxane
Water Sodium carbonate

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Preparation Products

Carbamic acid, N-(3-chloro-3-oxopropyl)-, 9H-fluoren-9-ylmethyl ester FMOC-BETA-ALA-OPFP

FMOC-b-Ala-OH Suppliers

Global( 358)Suppliers
Supplier Tel Email Country ProdList Advantage
Hangzhou ICH Biofarm Co., Ltd 		+86-0571-28186870; +undefined8613073685410 sales@ichemie.com China 1006 58
Sichuan HongRi Pharma-Tech Co.,Ltd 		+8617390183901 cynthia@enlaibio.com China 1098 58
ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD 		+86-13017695106 +86-13676922317 jiuyitime@fdachem.com China 16513 58
Capot Chemical Co.,Ltd. 		+86-（0）57185586718; +8613336195806 sales@capot.com China 29735 60
Henan Tianfu Chemical Co.,Ltd. 		+86-0371-55170693 +86-19937530512 info@tianfuchem.com China 21599 55
ATK CHEMICAL COMPANY LIMITED 		+undefined-21-51877795 ivan@atkchemical.com China 33024 60
career henan chemical co 		+86-0371-86658258 +8613203830695 sales@coreychem.com China 29833 58
Accela ChemBio Inc. 		+1-858-6993322 info@accelachem.com United States 21193 58
Chengdu Pukang Biotechnology Co., Ltd 		028-82550498 export@pu-kang.com CHINA 210 58
Xiamen AmoyChem Co., Ltd 		+86-86-5926051114 +8615060885618 sales@amoychem.com China 6369 58
Supplier Advantage
Hangzhou ICH Biofarm Co., Ltd 		58
Sichuan HongRi Pharma-Tech Co.,Ltd 		58
ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD 		58
Capot Chemical Co.,Ltd. 		60
Henan Tianfu Chemical Co.,Ltd. 		55
ATK CHEMICAL COMPANY LIMITED 		60
career henan chemical co 		58
Accela ChemBio Inc. 		58
Chengdu Pukang Biotechnology Co., Ltd 		58
Xiamen AmoyChem Co., Ltd 		58

View Lastest Price from FMOC-b-Ala-OH manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Fmoc-β-Ala-OH pictures 2026-01-30 Fmoc-β-Ala-OH
35737-10-1
 US $0.00-0.00 / kg 1kg 98% 1T Sichuan HongRi Pharma-Tech Co.,Ltd
FMOC-beta-Ala-OH pictures 2026-01-30 FMOC-beta-Ala-OH
35737-10-1
 US $0.00 / Kg/Drum 1KG 98%min 500kgs WUHAN FORTUNA CHEMICAL CO., LTD
Fmoc-β-Alanine pictures 2026-01-04 Fmoc-β-Alanine
35737-10-1
 US $0.00 / Box 1Box 99% 200kg Hangzhou ICH Biofarm Co., Ltd
  • Fmoc-β-Ala-OH pictures
  • Fmoc-β-Ala-OH
    35737-10-1
  • US $0.00-0.00 / kg
  • 98%
  • Sichuan HongRi Pharma-Tech Co.,Ltd
  • FMOC-beta-Ala-OH pictures
  • FMOC-beta-Ala-OH
    35737-10-1
  • US $0.00 / Kg/Drum
  • 98%min
  • WUHAN FORTUNA CHEMICAL CO., LTD

FMOC-b-Ala-OH Spectrum

FMOC-b-Ala-OH(35737-10-1)1HNMR

35737-10-1(FMOC-b-Ala-OH)Related Search:

β-Alanine Fmoc-L-glutamic acid FMOC-L-Valine FMOC-L-Methionine Fmoc-L-glutamic acid-gamma-benzyl ester
Fmoc-L-hydroxyproline FMOC-CHG-OH Nalpha-FMOC-L-Tryptophan Fmoc-Phe-OH Nalpha-Fmoc-L-tyrosine
FMOC-BETA-ALA-OPFP FMOC-BETA-ALANINOL FMOC-LYS-OH Di-tert-butyl dicarbonate D-Tyrosine
S-Trityl-L-cysteine L-Leucine L-Phenylalanine

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3-Fmoc-aminopropanoic acid Fmoc-β-alanine≥ 99% (HPLC) FMOC--ALA-OH Novabiochem N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-β-alanine FMOC-GLY(C*CH2)-OH FMOC-L-BETA-ALA-OH FMOC-NH-(CH2)2-COOH FMOC-BETA-ALANINE FMOC-BETA-ALA-OH FMOC-b-Ala-OH RARECHEM EM WB 0004 N-9-FLUORENYLMETHYLOXYCARBONYL-BETA-ALANINE N-(9-FLUORENYLMETHOXYCARBONYL)-BETA-ALANINE N-ALPHA-(9-FLUORENYLMETHYLOXYCARBONYL)-BETA-ALANINE N-BETA-(9-FLUORENYLMETHOXYCARBONYL)-BETA-ALANINE N-BETA-FMOC-BETA-ALANINE N-FMOC-BETA-ALANINE -Ala-OPfp Fmoc-β-Ala-OH P 3-(9H-FLUOREN-9-YLMETHOXYCARBONYLAMINO)-PROPIONIC ACID 9-FLUORENYLMETHOXYCARBONYL-BETA-ALANINE Fmoc-ß-Ala-OH FMOC --ALANINE 98.5+% FMOC-SS-ALA-OH N-β-Fmoc-β-alanine 9-fluorenylmethyloxycarbonyl-beta-alanine-OH FMOC-beta-Alanine,98% NALPHA-9-Fluorenylmethoxycarbonyl-B-alanine FMOC-B-ALANINE N-beta-FMoc--alanine N-[(9H-fluoren-9-ylmethoxy)carbonyl]-beta-alanine FMoc-β-Ala-OH FMoc-β-Alanine 3-((((9H-Fluoren-9-yl)Methoxy)carbonyl)aMino)propanoic acid L-ALANINE-N-FMOC (15N, 98%) FMoc-ß FMoc-&beta FMoc-B-Ala FMoc-Beta-Ala Fmoc-beta-Ala-OH >=99.0% (HPLC) Fmoc-S-Ala-OH FMoc-βFMoc-B-Ala N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-β-alanine> FMOC-b-AL FMoc-β-Ala-OH 3-(9H-fluoren-9-ylmethoxycarbonylamino)propanoicaci FMOC-b-Ala-OH USP/EP/BP Fmoc-β-alanine N-Fmoc-β-alanine Fmoc-β-Ala-OH, ≥99% (HPLC) 35737-10-1 FMOC-b-Ala-OH β-Alanine, N-[(9H-fluoren-9-ylmethoxy)carbonyl]- Fmoc-?-Alanine -Ala-OH Impurity IIa-7 (N-fluorenylmethoxycarbonyl - β - alanine) Fmoc-β-Ala-OH P fmoc-β-ala 35737-10-1 35737-15-1