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4-PIPERAZIN-1-YL-PHENYLAMINE

4-PIPERAZIN-1-YL-PHENYLAMINE structure

CAS No.: 67455-41-8

Chemical Name:: 4-PIPERAZIN-1-YL-PHENYLAMINE

Synonyms: TIMTEC-BB SBB010619;4-PIPERAZINOANILINE;4-PIPERAZIN-1-YLANILINE;4-(1-Piperazinyl)aniline;4-(4-AMinophenyl)piperazine;4-PIPERAZIN-1-YL-PHENYLAMINE;4-(1-Piperazinyl)aniline, 97%;1-(4-AMINO-PHENYL)-PIPERAZINE;1-(4-AMinophenyl)piperazine 97%;BenzenaMine, 4-(1-piperazinyl)-

CBNumber:: CB9452907

Molecular Formula:: C10H15N3

Molecular Weight:: 177.25

MDL Number:: MFCD01365906

MOL File:: 67455-41-8.mol

MSDS File:: SDS

Last updated:2026-01-13 11:27:11

Product description	Number	Pack Size	Price
1-(4-Aminophenyl)piperazine	A615655	50mg	$60
4-Piperazin-1-ylaniline 96%	3H30-1-WD	1g	$96
4-(Piperazin-1-yl)aniline	0375AC	1g	$104
1-(4-Aminophenyl)piperazine 97%	081179	1g	$147
4-Piperazin-1-ylaniline 96%	3H30-1-WD	5G	$288

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4-PIPERAZIN-1-YL-PHENYLAMINE Properties

Melting point	119-123 °C (lit.)
Boiling point	380.2±27.0 °C(Predicted)
Density	1.107±0.06 g/cm3(Predicted)
storage temp.	2-8°C, protect from light
form	Powder
pka	9.12±0.10(Predicted)
color	White to purple
InChI	1S/C10H15N3/c11-9-1-3-10(4-2-9)13-7-5-12-6-8-13/h1-4,12H,5-8,11H2
InChIKey	VAVOYRCCWLRTMS-UHFFFAOYSA-N
SMILES	Nc1ccc(cc1)N2CCNCC2
UNSPSC Code	12352100

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS05,GHS07,GHS06

Signal word

Danger

Hazard statements

H301-H302-H315-H318-H335

Precautionary statements

P261-P280-P305+P351+P338-P280a-P301+P310a-P405-P501a

target organs

Respiratory system

PPE

dust mask type N95 (US), Eyeshields, Gloves

Hazard Codes

Risk Statements

22-37/38-41

Safety Statements

26-39

WGK Germany

HS Code

2933998090

Storage Class

11 - Combustible Solids

Hazard Classifications

Acute Tox. 4 Oral
Eye Dam. 1
Skin Irrit. 2
STOT SE 3

NFPA 704

	0
2		0

4-PIPERAZIN-1-YL-PHENYLAMINE price More Price(19)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
TRC	A615655	1-(4-Aminophenyl)piperazine	67455-41-8	50mg	$60	2021-12-16	Buy
SynQuest Laboratories	3H30-1-WD	4-Piperazin-1-ylaniline 96%	67455-41-8	1g	$96	2021-12-16	Buy
AK Scientific	0375AC	4-(Piperazin-1-yl)aniline	67455-41-8	1g	$104	2021-12-16	Buy
Matrix Scientific	081179	1-(4-Aminophenyl)piperazine 97%	67455-41-8	1g	$147	2021-12-16	Buy
SynQuest Laboratories	3H30-1-WD	4-Piperazin-1-ylaniline 96%	67455-41-8	5G	$288	2021-12-16	Buy

Product number	Packaging	Price	Buy
A615655	50mg	$60	Buy
3H30-1-WD	1g	$96	Buy
0375AC	1g	$104	Buy
081179	1g	$147	Buy
3H30-1-WD	5G	$288	Buy

4-PIPERAZIN-1-YL-PHENYLAMINE Chemical Properties,Uses,Production

Uses

4-Piperazinoaniline(CAS#67455-41-8)is a important organic intermediate. It can be used in agrochemical, pharmaceutical and dyestuff field.

Synthesis

6269-89-2

67455-41-8

General procedure for the synthesis of 1-(4-aminophenyl)piperazine from 1-(4-nitrophenyl)piperazine: 1-(4-nitrophenyl)piperazine (414 mg, 2 mmol) was dissolved in a mixed solvent of ethanol (15 mL) and tetrahydrofuran (15 mL), and 10% palladium/carbon catalyst (50 mg) was added. The reaction was stirred for 3 h at room temperature under hydrogen atmosphere. The progress of the reaction was monitored by thin layer chromatography (TLC) during the reaction. Upon completion of the reaction, the reaction mixture was filtered through a diatomaceous earth pad to remove the catalyst. The filtrate was concentrated under reduced pressure to afford the target product 1-(4-aminophenyl)piperazine (319 mg, 90.0% yield).

References

[1] Synthetic Communications, 2012, vol. 42, # 2, p. 213 - 222
[2] RSC Advances, 2015, vol. 5, # 113, p. 93433 - 93437
[3] Green Chemistry, 2017, vol. 19, # 14, p. 3400 - 3407
[4] Tetrahedron Letters, 1999, vol. 40, # 31, p. 5655 - 5659
[5] Synthesis and Reactivity in Inorganic, Metal-Organic and Nano-Metal Chemistry, 2011, vol. 41, # 1, p. 114 - 119

4-PIPERAZIN-1-YL-PHENYLAMINE Preparation Products And Raw materials

Raw materials

1-(4-Nitrophenyl)piperazine Hydrogen Activated carbon Palladium Ethanol

Tetrahydrofuran

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Preparation Products

1-(4-Aminophenyl)-4-(4-hydroxyphenyl)piperazine 1-[4-(4,4,5,5-Tetramethyl-[1,3,2]dioxaborolan-2-yl)-phenyl]-piperazine

4-PIPERAZIN-1-YL-PHENYLAMINE Suppliers

Global( 86)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Hubei xin bonus chemical co. LTD	86-13657291602	linda@hubeijusheng.com	CHINA	22963	58
Alchem Pharmtech,Inc.	8485655694	sales@alchempharmtech.com	United States	63687	58
CONIER CHEM AND PHARMA LIMITED	+8618523575427	sales@conier.com	China	49977	58
Zhengzhou Alfa Chemical Co.,Ltd	+8618530059196	sale04@alfachem.cn	China	11727	58
Dideu Industries Group Limited	+86-29-89586680 +86-15129568250	1026@dideu.com	China	19282	58
Zhejiang J&C Biological Technology Co.,Limited	+1-2135480471 +1-2135480471;	sales@sarms4muscle.com	China	10473	58
Shanghai Acmec Biochemical Technology Co., Ltd.	+86-18621343501; +undefined18621343501	product@acmec-e.com	China	33325	58
Shanghai Likang New Materials Co., Limited	+86-16631818819 +86-17736933208	3684455296@qq.com	China	9300	58
SHANGHAI KEAN TECHNOLOGY CO., LTD.	+8613817748580	cooperation@kean-chem.com	China	40066	58
Alfa Aesar	400-6106006	saleschina@alfa-asia.com	China	30123	84

Supplier	Advantage
Hubei xin bonus chemical co. LTD	58
Alchem Pharmtech,Inc.	58
CONIER CHEM AND PHARMA LIMITED	58
Zhengzhou Alfa Chemical Co.,Ltd	58
Dideu Industries Group Limited	58
Zhejiang J&C Biological Technology Co.,Limited	58
Shanghai Acmec Biochemical Technology Co., Ltd.	58
Shanghai Likang New Materials Co., Limited	58
SHANGHAI KEAN TECHNOLOGY CO., LTD.	58
Alfa Aesar	84

View Lastest Price from 4-PIPERAZIN-1-YL-PHENYLAMINE manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2025-11-18	4-PIPERAZIN-1-YL-PHENYLAMINE 67455-41-8	US $1.10 / g	1g	99.00%	100 Tons	Dideu Industries Group Limited
	2021-07-02	1-(4-Aminophenyl)piperazine 67455-41-8	US $15.00-10.00 / KG	1KG	99%+ HPLC	Monthly supply of 1 ton	Zhuozhou Wenxi import and Export Co., Ltd

4-PIPERAZIN-1-YL-PHENYLAMINE
67455-41-8
US $1.10 / g
99.00%
Dideu Industries Group Limited

1-(4-Aminophenyl)piperazine
67455-41-8
US $15.00-10.00 / KG
99%+ HPLC
Zhuozhou Wenxi import and Export Co., Ltd

4-PIPERAZIN-1-YL-PHENYLAMINE Spectrum

4-PIPERAZIN-1-YL-PHENYLAMINE(67455-41-8)¹HNMR

67455-41-8(4-PIPERAZIN-1-YL-PHENYLAMINE)Related Search:

1-METHYL-4-(4-NITROPHENYL)PIPERAZINE 1-(4-Nitrophenyl)piperazine 4-(4-Methylpiperazino)aniline 2-PIPERAZIN-1-YL-PHENYLAMINE 3-(4-Methylpiperazin-1-yl)aniline

3-CHLORO-4-(4-METHYL-PIPERAZIN-1-YL)-PHENYLAMINE 3-Fluoro-4-(4-methylpiperazin-1-yl)aniline 2-(4-METHYL-PIPERAZIN-1-YL)-PHENYLAMINE 4-[4-(4-METHYLOXY-PHENYL)-PIPERAZIN-1-YL]-PHENYLAMINE 4-(4-ETHYL-PIPERAZIN-1-YL)-PHENYLAMINE

BUTTPARK 83\09-70 N-[4-(4-METHYLPIPERAZINO)PHENYL]PENTANAMIDE 4-(4-BENZYL-PIPERAZIN-1-YL)-PHENYLAMINE N-[4-(4-METHYLPIPERAZINO)PHENYL]ACETAMIDE 2,2-DIMETHYL-N-[4-(4-METHYLPIPERAZINO)PHENYL]PROPANAMIDE

2-(4-METHANESULFONYL-PIPERAZIN-1-YL)-PHENYLAMINE 3-PIPERAZIN-1-YL-PHENYLAMINE DOUBLE HYDROCHLORIDE 2,4-BIS-(4-METHYL-PIPERAZIN-1-YL)-PHENYLAMINE

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