5-BROMO-2-CARBOXY-3-METHYLPYRIDINE
- CAS No.
- 886365-43-1
- Chemical Name:
- 5-BROMO-2-CARBOXY-3-METHYLPYRIDINE
- Synonyms
- 5-broMo-3-Methylpicolinic acid;5-BROMO-2-CARBOXY-3-METHYLPYRIDINE;5-BROMO-3-METHYLPICOLINIC ACID (TAX INVO;5-Bromo-3-methylpyridin-2-carboxylic acid;3-methyl-5-bromo-2-pyridinecarboxylic acid;5-bromo-3-methyl-2-pyridinecarboxylic acid;5-BROMO-3-METHYL-PYRIDINE-2-CARBOXYLIC ACID;2-Pyridinecarboxylicacid, 5-broMo-3-Methyl-;5-BROMO-2-CARBOXY-3-METHYLPYRIDINE ISO 9001：2015 REACH;5-Bromo-3-methylpicolinic acid, 5-Bromo-2-carboxy-3-methylpyridine
- CBNumber:
- CB9817678
- Molecular Formula:
- C7H6BrNO2
- Molecular Weight:
- 216.03
- MDL Number:
- MFCD07375125
- MOL File:
- 886365-43-1.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| 5-Bromo-3-methylpicolinic Acid | TRC-B688140-50G | 50g | $774 |
| 5-Bromo-3-methylpicolinic Acid | TRC-B688140-2.5G | 2.5g | $129 |
| 5-Bromo-3-methylpicolinic Acid | TRC-B688140-10G | 10g | $314 |
| 5-BROMO-3-METHYL-PYRIDINE-2-CARBOXYLIC ACID 97% | 56973 | 1G | $15 |
| 5-BROMO-3-METHYL-PYRIDINE-2-CARBOXYLIC ACID 97% | 56973 | 5G | $24 |
| More product size | |||
| Melting point | 161-163oC |
|---|---|
| Boiling point | 330.5±42.0 °C(Predicted) |
| Density | 1.692±0.06 g/cm3(Predicted) |
| storage temp. | under inert gas (nitrogen or Argon) at 2-8°C |
| solubility | DMSO (Slightly), Methanol (Slightly) |
| pka | 3.04±0.37(Predicted) |
| form | Powder |
| color | Off-white |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P280a-P304+P340-P305+P351+P338-P405-P501a | |||||||||
| RIDADR | UN2811 | |||||||||
| HS Code | 2933399990 | |||||||||
| NFPA 704 |
|
5-BROMO-2-CARBOXY-3-METHYLPYRIDINE price More Price(95)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TRC | TRC-B688140-50G | 5-Bromo-3-methylpicolinic Acid | 886365-43-1 | 50g | $774 | 2026-06-03 | Buy |
| TRC | TRC-B688140-2.5G | 5-Bromo-3-methylpicolinic Acid | 886365-43-1 | 2.5g | $129 | 2026-06-03 | Buy |
| TRC | TRC-B688140-10G | 5-Bromo-3-methylpicolinic Acid | 886365-43-1 | 10g | $314 | 2026-06-03 | Buy |
| AstaTech | 56973 | 5-BROMO-3-METHYL-PYRIDINE-2-CARBOXYLIC ACID 97% | 886365-43-1 | 1G | $15 | 2026-04-30 | Buy |
| AstaTech | 56973 | 5-BROMO-3-METHYL-PYRIDINE-2-CARBOXYLIC ACID 97% | 886365-43-1 | 5G | $24 | 2026-04-30 | Buy |
5-BROMO-2-CARBOXY-3-METHYLPYRIDINE Chemical Properties,Uses,Production
Uses
5-Bromo-3-methylpicolinic Acid is used to prepare oxazine derivatives as BACE inhibitors useful in treatment of neurological disorders.
Synthesis
156072-86-5
886365-43-1
Step B Synthesis of 5-bromo-3-methylpyridine-2-carboxylic acid: 5-bromo-3-methylpyridine-2-carbonitrile (3.9 g, 20 mmol) was dissolved in ethanol (30 mL), followed by the addition of 6.0 M aqueous sodium hydroxide solution (15 mL). The reaction mixture was stirred at 80 °C for 1.5 hours. Upon completion of the reaction, the reaction mixture was concentrated, diluted with water and extracted by partitioning with ethyl acetate (EtOAc). The aqueous phase was acidified to pH 2-3 with hydrochloric acid and the product was subsequently extracted with EtOAc. The organic phase was washed with saturated brine, dried over anhydrous sodium sulfate, filtered and concentrated to give the yellow solid product 5-bromo-3-methylpyridine-2-carboxylic acid (4.2 g, 98% yield).
References
[1] Patent: US2013/96144, 2013, A1. Location in patent: Paragraph 0390; 0391
[2] Patent: WO2008/100715, 2008, A1. Location in patent: Page/Page column 33-34
5-BROMO-2-CARBOXY-3-METHYLPYRIDINE Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 | info@fdachem.com | China | 20122 | 58 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 33024 | 60 |
| HaBo Hong Kong Co., Limited. | +86-25-18512596065 | info@habotech.com | CHINA | 933 | 58 |
| Accela ChemBio Inc. | +1-858-6993322 | info@accelachem.com | United States | 21193 | 58 |
| BTC Nantong Pharmaceuticals Technology Co.,Ltd | +86-0513-81283365 | Info@btcpharm.com | China | 251 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | factory@coreychem.com | China | 29792 | 58 |
| Fuxin Pharmaceutical | +86-021-021-50872116 +8613122107989 | contact@fuxinpharm.com | China | 10000 | 58 |
| Antai Fine Chemical Technology Co.,Limited | 18503026267 | info@antaichem.com | CHINA | 9636 | 58 |
| Guangzhou Yuheng Pharmaceutical Technology Co., Ltd | +8613580539051 | joe@yuhengpharm.com | CHINA | 21142 | 58 |
View Lastest Price from 5-BROMO-2-CARBOXY-3-METHYLPYRIDINE manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2025-12-01 | 5-BROMO-2-CARBOXY-3-METHYLPYRIDINE
886365-43-1
|
1KG | 98.0% | 10000KGS | Shaanxi Dideu New Materials Co. Ltd | ||
 |
2025-11-18 | 5-BROMO-2-CARBOXY-3-METHYLPYRIDINE
886365-43-1
|
$1.10 | 1g | 99.00% | 100 Tons min | Dideu Industries Group Limited | |
 |
2025-09-25 | 5-BROMO-2-CARBOXY-3-METHYLPYRIDINE
886365-43-1
|
$5.00 | 1KG | 98% | Henan Fengda Chemical Co., Ltd |
-
- 5-BROMO-2-CARBOXY-3-METHYLPYRIDINE
886365-43-1
- 98.0%
- Shaanxi Dideu New Materials Co. Ltd
-
- 5-BROMO-2-CARBOXY-3-METHYLPYRIDINE
886365-43-1
- $1.10
- 99.00%
- Dideu Industries Group Limited
-
- 5-BROMO-2-CARBOXY-3-METHYLPYRIDINE
886365-43-1
- $5.00
- 98%
- Henan Fengda Chemical Co., Ltd
