Estradiol manufacturers and suppliers

Estradiol suppliers

Properties

Melting point:: 176-180 °C(lit.)

alpha: D20 +53 to +56° (c = 0.9 in dioxane)

Boiling point:: 355.44°C (rough estimate)

Density: 1.0708 (rough estimate)

refractive index: 1.4800 (estimate)

storage temp.: Sealed in dry,Room Temperature

solubility: ethanol: 50 mg/mL, clear, colorless

form: powder

pka: 10.27±0.60(Predicted)

color: white with slight yellow

biological source: synthetic (organic)

Water Solubility: 3.9mg/L(25 ºC)

Merck: 14,3704

InChI: 1S/C18H24O2/c1-18-9-8-14-13-5-3-12(19)10-11(13)2-4-15(14)16(18)6-7-17(18)20/h3,5,10,14-17,19-20H,2,4,6-9H2,1H3/t14-,15-,16+,17-,18+/m1/s1

InChIKey: VOXZDWNPVJITMN-SFFUCWETSA-N

SMILES: [H][C@]12CC[C@]3(C)[C@H](O)CC[C@@]3([H])[C@]1([H])CCc4cc(O)ccc24

CAS DataBase Reference: 57-91-0(CAS DataBase Reference)

NIST Chemistry Reference: Estra-1,3,5(10)-triene-3,17alpha-diol(57-91-0)

EPA Substance Registry System: Estra-1,3,5(10)-triene-3,17-diol, (17.alpha.)- (57-91-0)

Safety Information

Symbol(GHS): GHS08,GHS09

Signal word: Danger

Hazard statements: H341-H351-H360F-H362-H410

Precautionary statements: P201-P202-P260-P263-P273-P308+P313

PPE: dust mask type N95 (US), Eyeshields, Gloves

Hazard Codes: T,Xn

Risk Statements: 45-48-40

Safety Statements: 53-45-24/25-22

RIDADR: UN 2811 6.1/PG 2

WGK Germany: 3

RTECS: KG3750000

F: 8-10

HS Code: 29372390

Storage Class: 6.1C - Combustible acute toxic Cat.3
toxic compounds or compounds which causing chronic effects

Hazard Classifications: Aquatic Chronic 1
Carc. 2
Lact.
Muta. 2
Repr. 1A

Use

Estradiol (known as α-Estradiol or 17 α-Estradiol) is a biologically active estrogen in human breast cancer cells in tissue culture. 17-Εstradiol and its selective receptor, ER-X, are not part of a classical hormone/receptor endocrine system but of a system with important autocrine/paracrine functions in the developing and adult brain. 17-Estradiol may have enormous implications for hormone replacement strategies at the menopause and in the treatment of such neurodegenerative disorders as Alzheimer’s disease and ischemic stroke.

You can find Estradiol suppliers, manufacturers, and distributors from countries such as China, United States and the India here. Browse to the tetrahydrofuran product information displayed by the supplier, as well as the supplier's contact and capability information.