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| | Methyl 4-aza-5alpha-androsta-1-en-3-one-17beta-carboxylate Basic information |
| Product Name: | Methyl 4-aza-5alpha-androsta-1-en-3-one-17beta-carboxylate | | Synonyms: | METHYL 3-OXO-4-AZA-5-ALPHA-ANDROST-1-ENE-17-BETA-CARBOXYLATE;3-Oxo-4-aza-5α-αndrost-1-ene-17β-carboxylic Acid Methyl Ester;(4aR,4bS,6aS,7S,9aS,9bS,11aR)-2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-Tetradecahydro-4a,6a-diMethyl-2-oxo-;Finasteride Methyl Ester Analog;(4aR,4bS,6aS,7S,9aS,9bS,11aR)-Methyl 4a,6a-dimethyl-2-oxo-2,4a,4b,5,6,6a,7, 8,9,9a,9b,10,11,11a-t;(4aR,4bS,6aS,7S,9aS,9bS,11aR);-Methyl 4a,6a-dimethyl-2-oxo-2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-indeno[5,4-f]quinoline-7-carboxylate;methyl (1S,3aS,3bS,5aR,9aR,9bS,11aS)-9a,11a-dimethyl-7-oxo-1,2,3,3a,3b,4,5,5a,6,9b,10,11-dodecahydroindeno[5,4-f]quinoline-1-carboxylate | | CAS: | 103335-41-7 | | MF: | C20H29NO3 | | MW: | 331.45 | | EINECS: | 600-422-0 | | Product Categories: | Intermediates;Intermediates & Fine Chemicals;Pharmaceuticals;Steroids | | Mol File: | 103335-41-7.mol |  |
| | Methyl 4-aza-5alpha-androsta-1-en-3-one-17beta-carboxylate Chemical Properties |
| Melting point | 280-282°C (dec.) | | Boiling point | 478.6±45.0 °C(Predicted) | | density | 1.113±0.06 g/cm3(Predicted) | | storage temp. | Sealed in dry,2-8°C | | solubility | Chloroform (Slightly), DMSO (Slightly, Heated), Methanol (Slightly, Heated) | | form | Solid | | pka | 14.15±0.70(Predicted) | | color | White to Off-White | | InChIKey | WMSQGMYJYBSBKA-ALHYADCGSA-N | | SMILES | N1[C@@]2([H])[C@@](C)([C@@]3([H])CC[C@@]4(C)[C@]([H])([C@]3([H])CC2)CC[C@@H]4C(OC)=O)C=CC1=O |
| | Methyl 4-aza-5alpha-androsta-1-en-3-one-17beta-carboxylate Usage And Synthesis |
| Chemical Properties | Off-White Solid | | Uses | Finasteride (F342000) and Dutasteride (D735000) impurity. An intermediate in the synthesis of Finasteride and Dutasteride, 5α-reductase inhibitors used for treatment of benign prostatic hyperplasia ac
ne, seborrhea, female hirsutism, prostatitis, and prostatic carcinoma and other hyperandrogenetic related disorders. | | Uses | 3-Oxo-4-aza-5α-αndrost-1-ene-17β-carboxylic Acid Methyl Ester (Finasteride EP Impurity B) is an impurity of Finasteride (F342000) and Dutasteride (D735000). An intermediate in the synthesis of Finasteride and Dutasteride, 5α-reductase inhibitors used for treatment of benign prostatic hyperplasia acne, seborrhea, female hirsutism, prostatitis, and prostatic carcinoma and other hyperandrogenetic related disorders. Finasteride impurity. | | Uses | Finasteride (F342000) impurity. A novel intermediate in the synthesis of Finasteride, a 5α-reductase inhibitor used for treatment of benign prostatic hyperplasia acne, seborrhea, female hirsutism, prostatitis, and prostatic carcinoma and other hyperandrogenetic related disorders. |
| | Methyl 4-aza-5alpha-androsta-1-en-3-one-17beta-carboxylate Preparation Products And Raw materials |
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