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| | (2R,3S)-3-Phenylisoserine ethylester Basic information |
| Product Name: | (2R,3S)-3-Phenylisoserine ethylester | | Synonyms: | Ethyl (2R,3S)-3-(benzoylamino)-2-hydroxybenzenepropanoate;Ethyl(2R,3S)-3-(benzoylaMino)-2-hydroxybenzenepropanoale;BENZYLOXYPHENYLISOSERINE ETHYLESTER,N-(P);(2R,3S)- Phenylisoserine ethylester;Benzenepropanoic acid, b-(benzoylamino)-a-hydroxy-, ethyl ester, (aR,bS)-;TAXOL SIDE CHAIN ETHYL ESTER(SH);(αR,βS)-β-(BenzoylaMino)-α-hydroxybenzenepropanoic Acid Ethyl Ester;(2R,3S)-N-Benzoyl-3-phenyl Isoserine Eth | | CAS: | 153433-80-8 | | MF: | C18H19NO4 | | MW: | 313.35 | | EINECS: | 1806241-263-5 | | Product Categories: | Amino Acids & Derivatives;Anti-virals;Aromatics;Intermediates & Fine Chemicals;Pharmaceuticals | | Mol File: | 153433-80-8.mol |  |
| | (2R,3S)-3-Phenylisoserine ethylester Chemical Properties |
| Melting point | 162~163℃ | | Boiling point | 546.8±50.0 °C(Predicted) | | density | 1.211±0.06 g/cm3(Predicted) | | solubility | Chloroform, Ethyl Acetate, Methanol | | form | Solid | | pka | 12.19±0.20(Predicted) | | color | White | | CAS DataBase Reference | 153433-80-8 |
| | (2R,3S)-3-Phenylisoserine ethylester Usage And Synthesis |
| Chemical Properties | White Solid | | Uses | (2R,3S)-3-PHENYLISOSERINE ETHYLESTER is an intermediate in the preparation of potent anticancer drug Paclitaxel (P132500) used to study the location of the binding sites. (2R,3S)-3-PHENYLISOSERINE ETHYLESTER shows cytotoxic, antiviral and immunomodulatory activity. | | Synthesis | The conventional synthesis of ethyl (2R,3S)-3-(benzoylamino)-2-hydroxybenzenepropanoate is mainly made by asymmetric bis-hydroxylation of ,-unsaturated esters, followed by azide substitution and reduction. |
| | (2R,3S)-3-Phenylisoserine ethylester Preparation Products And Raw materials |
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