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| | 4,6-Dihydroxypyrimidine Basic information |
| Product Name: | 4,6-Dihydroxypyrimidine | | Synonyms: | 4,6-Dihydroxypyrimidine, 4,6-Dihydroxy-1,3-diazine;4,6- twohydroxy pyriMidine;4, 6-2 hydroxy pyriMidine;DihydroxypyriMidine;4,6-DIHYDROXYPYRIMIDINE;4(1H)-PYRIMIDINONE, 6-HYDROXY-;NSC 22838;4,6-DIHYDROXYPYRIMIDINE FOR SYNTHESIS | | CAS: | 1193-24-4 | | MF: | C4H4N2O2 | | MW: | 112.09 | | EINECS: | 214-772-3 | | Product Categories: | Bases & Related Reagents;Nucleotides;Pyrimidines;Nucleotides and Nucleosides;FINE Chemical & INTERMEDIATES;PYRIMIDINE;APIs & Intermediate;Building Blocks;C4 to C5;Chemical Synthesis;Heterocyclic Building Blocks;Heterocycle-Pyrimidine series;bc0001 | | Mol File: | 1193-24-4.mol |  |
| | 4,6-Dihydroxypyrimidine Chemical Properties |
| Melting point | >300 °C (lit.) | | Boiling point | 209.98°C (rough estimate) | | density | 1.4421 (rough estimate) | | vapor pressure | 0.001Pa at 20℃ | | refractive index | 1.4610 (estimate) | | storage temp. | Inert atmosphere,Room Temperature | | solubility | 2.5 g/L (20° C) | | form | Powder | | pka | 5.70±0.10(Predicted) | | color | Yellow to orange | | Water Solubility | 2.5 g/L (20 º C) | | BRN | 606433 | | InChI | 1S/C4H4N2O2/c7-3-1-4(8)6-2-5-3/h1-2H,(H2,5,6,7,8) | | InChIKey | DUFGYCAXVIUXIP-UHFFFAOYSA-N | | SMILES | Oc1cc(O)ncn1 | | LogP | -2.8 at 25℃ | | CAS DataBase Reference | 1193-24-4(CAS DataBase Reference) | | NIST Chemistry Reference | 4(1H)-pyrimidinone, 6-hydroxy-(1193-24-4) | | EPA Substance Registry System | 6-Hydroxy-4(1H)-pyrimidinone (1193-24-4) |
| Hazard Codes | Xi | | Risk Statements | 36/37/38 | | Safety Statements | 26-36-37/39 | | WGK Germany | 1 | | RTECS | UW7523000 | | Hazard Note | Irritant | | TSCA | TSCA listed | | HS Code | 29335995 | | Storage Class | 11 - Combustible Solids |
| | 4,6-Dihydroxypyrimidine Usage And Synthesis |
| Chemical Properties | Light Yellow Powder | | Uses | 4,6-Dihydroxypyrimidine (cas# 1193-24-4) is a compound useful in organic synthesis. | | Definition | ChEBI: 4,6-dihydroxypyrimidine is a hydroxypyrimidine. | | Flammability and Explosibility | Not classified | | Synthesis | Synthesis of 4,6-dihydroxypyrimidine (DHP) by reaction of a malonic acid ester with formamide and an alkali metal alkoxide at elevated temperature. | | References | [1] Patent: CN106883186, 2017, A. Location in patent: Paragraph 0037; 0038; 0039; 0040; 0041; 0042; 0043-0052
[2] Patent: CN105859637, 2016, A. Location in patent: Paragraph 0020; 0021; 0022 |
| | 4,6-Dihydroxypyrimidine Preparation Products And Raw materials |
| Raw materials | Sodium Methoxide-->Diethyl malonate-->Formamide-->Malonic acid di-n-butyl ester-->formamide-->Dimethyl malonate-->Hydrochloric acid-->Water-->Methanol | | Preparation Products | Bensulfuron methyl-->4,5-Diaminopyrimidine-->4,6-Diamino-5-nitropyrimidine-->Chlorimuron-ethyl-->4,6-Dichloropyrimidine-->6-Chloro-5-nitropyrimidin-4-amine-->6-Amino-5-nitropyrimidin-4-ol-->5-Amino-4,6-dichloropyrimidine-->ETRIMFOS-->4,6-Dichloro-5-nitropyrimidine-->4-Amino-6-chloropyrimidin-5-ylamine-->4-Chloro-6-hydrazino-pyrimidin-5-ylamine-->5-Amino-6-chloro-pyrimidin-4-ol-->2-Amino-4,6-dichloropyrimidine-->5-Bromo-4,6-dichloropyrimidine-->4,6-Dichloropyrimidine-5-carbaldehyde-->4-Amino-6-chloropyrimidine-5-carbaldehyde-->4,6-Dihydroxy-5-nitropyrimidine-->2-(methylthio)pyrimidine-4,6-diol-->5-Bromo-4,6-dihydroxypyrimidine |
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