- Bisabolangelone
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- $44.00
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2026-07-27
- CAS:30557-81-4
- Purity: 99.65%
- Supply Ability: 10g
- Bisabolangelone
-
-
2026-06-30
- CAS:30557-81-4
- Min. Order: 1KG
- Purity: 98%
- Supply Ability: 20Tons
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| | (+)-Bisabolangelone Basic information |
| Product Name: | (+)-Bisabolangelone | | Synonyms: | (+)-Angelikoreanol;(+)-Bisabolangelone;Angelikoreanol;Bisabolangelon;Bisabplangelone;4(2H)-Benzofuranone, 3,3a,7,7a-tetrahydro-3-hydroxy-3,6-dimethyl-2-(3-methyl-2-buten-1-ylidene)-, (2Z,3R,3aR,7aS)-;Bisabolangelone,Inhibitor,inhibit,p38 MAPK;Ligustilone | | CAS: | 30557-81-4 | | MF: | C15H20O3 | | MW: | 248.32 | | EINECS: | | | Product Categories: | Miscellaneous | | Mol File: | 30557-81-4.mol |  |
| | (+)-Bisabolangelone Chemical Properties |
| Melting point | 157-158 °C | | Boiling point | 396.0±42.0 °C(Predicted) | | density | 1.154±0.06 g/cm3(Predicted) | | storage temp. | 4°C, protect from light | | solubility | Soluble in DMSO | | form | Solid | | pka | 14.54±0.40(Predicted) | | color | Off-white to yellow | | InChI | InChI=1S/C15H20O3/c1-9(2)5-6-13-15(4,17)14-11(16)7-10(3)8-12(14)18-13/h5-7,12,14,17H,8H2,1-4H3/b13-6-/t12-,14+,15-/m0/s1 | | InChIKey | GNWNPLBSEQDDQV-VRBKASCLSA-N | | SMILES | O1[C@@]2([H])CC(C)=CC(=O)[C@@]2([H])[C@](O)(C)/C/1=C/C=C(/C)\C |
| | (+)-Bisabolangelone Usage And Synthesis |
| Uses | Bisabolangelone, a sesquiterpene derivative, is isolated from the roots of Osterici Radix. Bisabolangelone possesses anti-inflammatory properties, which inhibits LPS-stimulated inflammation through the blocking of NF-kappaB and MAPK pathways in macrophages. Bisabolangelone has anti-ulcer activities[1][2]. | | References | [1] Jung HW, et al. Bisabolangelone isolated from Ostericum koreanum inhibits the production of inflammatory mediators by down-regulation of NF-kappaB and ERK MAP kinase activity in LPS-stimulated RAW264.7 cells. Int Immunopharmacol. 2010 Feb;10(2):155-62. DOI:10.1016/j.intimp.2009.10.010
[2] Wang J, et al. The anti-ulcer activities of bisabolangelone from Angelica polymorpha. J Ethnopharmacol. 2009 Jun 22;123(2):343-6. DOI:10.1016/j.jep.2009.02.048 |
| | (+)-Bisabolangelone Preparation Products And Raw materials |
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