- Shionone
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- $54.00
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2026-07-15
- CAS:10376-48-4
- Purity: 98.00%
- Supply Ability: 10g
- Shionone
-
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2023-02-24
- CAS:10376-48-4
- Min. Order: 5mg
- Purity: ≥98%(HPLC)
- Supply Ability: 10 g
- SHIONONE
-
- $1.00
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2019-07-06
- CAS:10376-48-4
- Min. Order: 1 mg
- Purity: 99%
- Supply Ability: 100KG
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| | SHIONONE Basic information | | Uses |
| Product Name: | SHIONONE | | Synonyms: | SHIONONE;2(1H)-Chrysenone,hexadecahydro-1,4b,6a,8,10a,12a-;hexamethyl-8-(4-methyl-3-pentenyl)-,(1R,4aS,4bS,6aS,8R,10aR,10bS,12aS)-;18,19-Seco-D:A-friedolup-19-en-3-one;3β,5,8,17aβ-Tetramethyl-3-(4-methyl-3-pentenyl)-D-homo-5α-androstan-17-one;Shionone ,98%;21-Shionen-3-one;Shionone, 98%, from Aster tataricus L. f. | | CAS: | 10376-48-4 | | MF: | C30H50O | | MW: | 426.72 | | EINECS: | | | Product Categories: | chemical reagent;pharmaceutical intermediate;phytochemical;reference standards from Chinese medicinal herbs (TCM).;standardized herbal extract | | Mol File: | 10376-48-4.mol |  |
| | SHIONONE Chemical Properties |
| Melting point | 161-162° | | alpha | D26.5 -56.1° (c = 1.07 in chloroform) | | Boiling point | 485.6±14.0 °C(Predicted) | | density | 0.941±0.06 g/cm3(Predicted) | | solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | | form | Powder | | color | White to off-white | | Optical Rotation | -56.126.5 (c 1.07, CHCl3) | | LogP | 10.401 (est) |
| Safety Statements | 24/25 | | HS Code | 29143990 |
| | SHIONONE Usage And Synthesis |
| Uses | Shionone is an effective inhibitor of human neutrophil elastase which may be used as a treatment for inflammatory lung diseases including H1N1 and SARS virus infections. | | Chemical Properties | White crystalline powder, soluble in organic solvents such as methanol, ethanol, and DMSO, derived from Aster tataricus. | | Uses | Shionone is an effective inhibitor of human neutrophil elastase which may be used as a treatment for inflammatory lung diseases including H1N1 and SARS virus infections. | | Definition | ChEBI: A tetracyclic triterpenoid that is perhydrochrysene which is substituted by methyl groups at positions 1, 4bbeta, 6aalpha, 8beta, 10abeta and 12a positions, by a 4-methylpent-3-enyl group
t the 8alpha position, and with an oxo group at position 2. | | in vivo | Shionone (orally administration; 80 mg/kg; 3 days; once daily) shows the trend of enhancing sputum secreting, but has no effect on ammonia-induced cough and reduces xylene-induced ear edema[1]. | Animal Model: | ICR male mice[1] | | Dosage: | 80 mg/kg | | Administration: | Orally administration; 3 days; once daily | | Result: | Reduced the ear edema for 11.3% by use shionone. |
| | target | ERK | IkB | NOS | IKK |
| | SHIONONE Preparation Products And Raw materials |
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