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2-AMINO-4-FLUOROPYRIDINE

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Products Intro: Product Name:2-amino-4-fluoropyridine
CAS:944401-77-8
Purity:98%(Min,HPLC) Package:100g;1kg;5kg,10kg,25kg,50kg
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CAS:944401-77-8
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Products Intro: Product Name:2-Amino-4-fluoropyridine
CAS:944401-77-8
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Products Intro: Product Name:2-AMINO-4-FLUOROPYRIDINE
CAS:944401-77-8
Purity:98% Package:10MG;50MG;100MG,1G,5G,10G.100G
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CAS:944401-77-8
Purity:97%-99% Package:1KG;8.8USD

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  • 2-AMINO-4-FLUOROPYRIDINE
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  • $1.10 / 1g
  • 2025-06-25
  • CAS:944401-77-8
  • Min. Order: 1g
  • Purity: 99.0% min
  • Supply Ability: 100 tons min
  • 2-Amino-4-fluoropyridine
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  • $0.00 / 1kg
  • 2022-04-22
  • CAS:944401-77-8
  • Min. Order: 0.0001kg
  • Purity: 98%min
  • Supply Ability: 100kgs/month
2-AMINO-4-FLUOROPYRIDINE Basic information
Product Name:2-AMINO-4-FLUOROPYRIDINE
Synonyms:2-Amino-4-fluoropyridine;4-Fluoropyridin-2-amine;2-PyridinaMine,4-fluoro-;4-Fluoro-pyridin-2-ylamine;4-FLUORO-2-PYRIDINAMINE;2-Amino-4-Fluoropyridine(WX609167);2-AMINO-4-FLUOROPYRIDINE ISO 9001：2015 REACH;22-Amino-4-fluoropyridine
CAS:944401-77-8
MF:C5H5FN2
MW:112.11
EINECS:815-037-5
Product Categories:Fluorine series;Pyridine;Amines;Pyridines
Mol File:944401-77-8.mol
2-AMINO-4-FLUOROPYRIDINE Structure
2-AMINO-4-FLUOROPYRIDINE Chemical Properties
Melting point 102 °C
Boiling point 211.5±20.0 °C(Predicted)
density 1.257±0.06 g/cm3(Predicted)
storage temp. Keep in dark place,Inert atmosphere,2-8°C
form Solid
pka6.42±0.11(Predicted)
color Pale yellow
Water Solubility Slightly soluble in water.
InChIInChI=1S/C5H5FN2/c6-4-1-2-8-5(7)3-4/h1-3H,(H2,7,8)
InChIKeyWCCFLOQQACDOAX-UHFFFAOYSA-N
SMILESC1(N)=NC=CC(F)=C1
Safety Information
HazardClass IRRITANT
HS Code 2933399990
MSDS Information
2-AMINO-4-FLUOROPYRIDINE Usage And Synthesis
Description2-Amino-4-fluoropyridine is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
Chemical PropertiesWhite powder
UsesIt is an important raw material and intermediate used in organic synthesis agrochemical, pharmaceutical and dyestuff field.
Uses2-Amino-4-fluoropyridine is an important intermediate for organic synthesis and pharmaceuticals.
Synthesis
2-Amino-4-chloropyridine

19798-80-2

2-AMINO-4-FLUOROPYRIDINE

944401-77-8

General procedure for the synthesis of 2-amino-4-fluoropyridine from 2-amino-4-chloropyridine: 28 g of 2-amino-4-chloropyridine was dissolved in 100 ml of N,N-dimethylformamide, followed by the addition of 46 g of sodium fluoride. The reaction mixture was heated to 140°C and kept reacting for 5 to 8 hours. Upon completion of the reaction, the mixture was cooled to 80 °C and the solvent was subsequently recovered by distillation under reduced pressure. The residue was dissolved in dichloromethane and washed with saturated saline. The organic phase was separated and after evaporation of the solvent, recrystallized from ethanol to give 22 g of white solid 2-amino-4-fluoropyridine in 90% yield.

References[1] Patent: CN108440402, 2018, A. Location in patent: Paragraph 0008; 0020; 0023-0024; 0027-0028; 0031
Tag:2-AMINO-4-FLUOROPYRIDINE(944401-77-8) Related Product Information
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