- 2-Iodobenzyl bromide
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- $10.00
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2025-04-15
- CAS:40400-13-3
- Min. Order: 1kg
- Purity: 99%
- Supply Ability: 20ton
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| | 2-Iodobenzyl bromide Chemical Properties |
| Melting point | 54-60 °C(lit.) | | Boiling point | 125 °C / 4mmHg | | density | 2.105±0.06 g/cm3(Predicted) | | Fp | >230 °F | | storage temp. | Keep in dark place,Inert atmosphere,2-8°C | | solubility | soluble in Methanol | | form | Crystalline Powder | | color | White to cream | | Sensitive | Light Sensitive | | BRN | 2079736 | | InChI | 1S/C7H6BrI/c8-5-6-3-1-2-4-7(6)9/h1-4H,5H2 | | InChIKey | GQFITODJWOIYPF-UHFFFAOYSA-N | | SMILES | BrCc1ccccc1I | | CAS DataBase Reference | 40400-13-3(CAS DataBase Reference) |
| Hazard Codes | C,N,T | | Risk Statements | 22-34-43-51/53-63-42/43-36/37/38 | | Safety Statements | 26-36/37/39-61-45-23 | | RIDADR | UN 3261 8/PG 2 | | WGK Germany | 2 | | HazardClass | 8 | | PackingGroup | Ⅱ | | HS Code | 29039990 | | Storage Class | 8A - Combustible corrosive hazardous materials | | Hazard Classifications | Acute Tox. 4 Oral
Resp. Sens. 1
Skin Corr. 1B |
| | 2-Iodobenzyl bromide Usage And Synthesis |
| Application | 2-Iodobenzylmethyl bromide is a halocarbon compound mainly used in laboratory research and development processes and chemical production processes. | | Chemical Properties | White solid | | Synthesis | General procedure for the synthesis of 2-iodobenzyl bromide from 2-iodobenzyl alcohol: 48% hydrobromic acid (10 mL) and 98% sulfuric acid (2 mL) were added to 2-iodobenzyl alcohol (0.94 g, 4.0 mmol). The resulting suspension was placed in an oil bath and heated and stirred at 150 °C for 2 hours. After completion of the reaction, the mixture was cooled to room temperature and extracted with dichloromethane (2 x 10 mL). The organic layers were combined, dried with anhydrous magnesium sulfate and concentrated under reduced pressure to give the crude product. The crude product was purified by fast column chromatography (silica gel, 0-20% dichloromethane/hexane gradient elution) to afford the target compound 2-iodobenzyl bromide (1.0 g, 84% yield). | | References | [1] Tetrahedron, 2005, vol. 61, # 13, p. 3311 - 3324
[2] Journal of Organic Chemistry, 2012, vol. 77, # 13, p. 5705 - 5713
[3] Helvetica Chimica Acta, 1995, vol. 78, p. 765 - 771
[4] Tetrahedron, 1993, vol. 49, # 20, p. 4439 - 4446
[5] Tetrahedron, 2002, vol. 58, # 44, p. 9007 - 9018 |
| | 2-Iodobenzyl bromide Preparation Products And Raw materials |
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