N-(Hydroxy-PEG3)-N-bis(PEG4-t-butyl ester) manufacturers
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| | N-(Hydroxy-PEG3)-N-bis(PEG4-t-butyl ester) Basic information |
| Product Name: | N-(Hydroxy-PEG3)-N-bis(PEG4-t-butyl ester) | | Synonyms: | N-(Hydroxy-PEG3)-N-bis(PEG4-t-butyl ester);N-(Hydroxy-PEG3)-N-bis(PEG4-Boc);4,7,10,13,19,22,25,28-Octaoxa-16-azahentriacontanedioic acid, 16-[2-[2-[2-(2-hydroxyethoxy)ethoxy]ethoxy]ethyl]-, 1,31-bis(1,1-dimethylethyl) ester;HUN 34708;Di-tert-butyl 16-(2-(2-(2-(2-hydroxyethoxy)ethoxy)ethoxy)ethyl)-4,7,10,13,19,22,25,28-octaoxa-16-azahentriacontanedioate | | CAS: | 2112734-70-8 | | MF: | C38H75NO16 | | MW: | 802 | | EINECS: | | | Product Categories: | | | Mol File: | 2112734-70-8.mol |  |
| | N-(Hydroxy-PEG3)-N-bis(PEG4-t-butyl ester) Chemical Properties |
| storage temp. | 2-8°C, protect from light | | form | Viscous Liquid | | color | Off-white to light yellow |
| | N-(Hydroxy-PEG3)-N-bis(PEG4-t-butyl ester) Usage And Synthesis |
| Description | N-(Hydroxy-PEG3)-N-bis(PEG4-t-butyl ester) is a branched PEG linker with a terminal hydroxy group and two t-butyl esters. The hydroxy group enables further derivatization or replacement with other reactive functional groups. The t-butyl protected carboxyl groups can be deprotected under mild acidic conditions. | | Uses | N-(Hydroxy-PEG3)-N-bis(PEG4-Boc) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. | | IC 50 | PEGs; Alkyl/ether | | References | [1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005 |
| | N-(Hydroxy-PEG3)-N-bis(PEG4-t-butyl ester) Preparation Products And Raw materials |
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