N-Boc-N-bis(PEG4-NHS ester) manufacturers
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| | N-Boc-N-bis(PEG4-NHS ester) Basic information |
| Product Name: | N-Boc-N-bis(PEG4-NHS ester) | | Synonyms: | N-Boc-N-bis(PEG4-NHS ester);3,6,9,12,18,21,24,27-Octaoxa-15-azanonacosane-1,15,29-tricarboxylic acid, 15-(1,1-dimethylethyl) 1,29-bis(2,5-dioxo-1-pyrrolidinyl) ester | | CAS: | 2093153-08-1 | | MF: | C35H57N3O18 | | MW: | 807.84 | | EINECS: | | | Product Categories: | | | Mol File: | 2093153-08-1.mol |  |
| | N-Boc-N-bis(PEG4-NHS ester) Chemical Properties |
| Boiling point | 799.8±70.0 °C(Predicted) | | density | 1.29±0.1 g/cm3(Predicted) | | pka | -1.61±0.70(Predicted) |
| | N-Boc-N-bis(PEG4-NHS ester) Usage And Synthesis |
| Description | N-Boc-N-bis(PEG4-NHS ester) is a branched PEGylation reagent. The NHS esters can be used to label proteinsor other amine-attached molecules. Boc can be removed under acidic conditions. | | Uses | N-Boc-N-bis(PEG4-NHS ester) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. | | IC 50 | PEGs; Alkyl/ether | | References | [1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005 |
| | N-Boc-N-bis(PEG4-NHS ester) Preparation Products And Raw materials |
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