(R)-(-)-Phenylsuccinic acid

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(R)-(-)-Phenylsuccinic acid manufacturers

(R)-(-)-Phenylsuccinic acid Basic information
Product Name:(R)-(-)-Phenylsuccinic acid
Synonyms:(R)2-Phenylsuccinicacid;(R)-(-)-PHENYLSUCCINIC ACID;(R)-(-)-PHENYLSUCCINIC ACID 99+%;(R)-2-Phenylbutanedioic acid;Butanedioic acid, 2-phenyl-, (2R)-;(R)-(-)-Phenylsuccinic acid >=96.0% (sum of enantiomers, HPLC);(2R)-2-Phenylbutanedioic acid;(2R)-2-Phenylbutanedioicacid>99%ee
CAS:46292-93-7
MF:C10H10O4
MW:194.18
EINECS:
Product Categories:Miscellaneous;Carboxylic Acids;Chiral Building Blocks;Organic Building Blocks
Mol File:46292-93-7.mol
(R)-(-)-Phenylsuccinic acid Structure
(R)-(-)-Phenylsuccinic acid Chemical Properties
Melting point 173-176 °C
alpha -175 º (c=1%, acetone)
Boiling point 290.62°C (rough estimate)
density 1.2534 (rough estimate)
refractive index 1.5430 (estimate)
storage temp. Sealed in dry,Room Temperature
solubility Acetone (Slightly), Methanol (Slightly)
form Solid
pka3.60±0.10(Predicted)
color White to Off-White
Optical Rotation[α]20/D 175±4°, c = 1% in acetone
BRN 3201702
InChIInChI=1S/C10H10O4/c11-9(12)6-8(10(13)14)7-4-2-1-3-5-7/h1-5,8H,6H2,(H,11,12)(H,13,14)/t8-/m1/s1
InChIKeyLVFFZQQWIZURIO-MRVPVSSYSA-N
SMILESC(O)(=O)[C@@H](C1=CC=CC=C1)CC(O)=O
CAS DataBase Reference46292-93-7(CAS DataBase Reference)
Safety Information
Safety Statements 22-24/25
WGK Germany 3
HS Code 2917399590
Storage Class13 - Non Combustible Solids
MSDS Information
ProviderLanguage
SigmaAldrich English
(R)-(-)-Phenylsuccinic acid Usage And Synthesis
Chemical Propertiesalmost white fine powder
Uses(R)-Phenylsuccinic Acid is an intermediate used in the preparation of optically active succinic acid derivatives used as hypoglycemic agents.
DefinitionChEBI: 2-Phenylsuccinic acid is a member of benzenes and a monocarboxylic acid.
Purification MethodsPurify the acids by re-precipitation from alkali and recrystallisation from H2O. [Naps & Johns J Am Chem Soc 62 2450 1940, Fredga & Matell Bull Soc Chim Belg 62 47 1953, Wren & Williams J Chem Soc 109 572 1916.] The racemate [635-51-8] has m 166-168o, 168o after recrystallisation from H2O or MeCN. Its S-benzylisothiuronium salt has m 164-165o (from EtOH) [Griediger & Pedersen Acta Chem Scand 9 1425 1955]. [Beilstein 9 IV 3351.]
(R)-(-)-Phenylsuccinic acid Preparation Products And Raw materials
Tag:(R)-(-)-Phenylsuccinic acid(46292-93-7) Related Product Information
Succimer Hyaluronic acid Folic acid Diethyl succinosuccinate Metroprolol succinate Disodium succinate DL-Phenylsuccinic acid Succinic acid iron succinate 2,3-Dibromosuccinic acid Ethyl 2-(Chlorosulfonyl)acetate Citric acid Sulfosuccinic acid Dodecenylsuccinic acid Ascoric Acid (S)-(+)-Phenylsuccinic acid, 99+%,(S)-(+)-PHENYLSUCCINIC ACID N-(4-Carboxyphenyl)succinamic acid (R)-(+)-2-Benzylsuccinic acid 1-methyl ester