ChemicalBook > Product Catalog >Pharmaceutical intermediates >Bulk Drug Intermediates >(2R,5S,13aR)-8-methoxy-7,9-dioxo-2,3,4,5,7,9,13,13a-octahydro-2,5-methanopyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazepine-10-carboxylic acid

(2R,5S,13aR)-8-methoxy-7,9-dioxo-2,3,4,5,7,9,13,13a-octahydro-2,5-methanopyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazepine-10-carboxylic acid

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(2R,5S,13aR)-8-methoxy-7,9-dioxo-2,3,4,5,7,9,13,13a-octahydro-2,5-methanopyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazepine-10-carboxylic acid Suppliers list
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Products Intro: Product Name:(2R,5S,13aR)-8-methoxy-7,9-dioxo-2,3,4,5,7,9,13,13a-octahydro-2,5-methanopyrido[1',2':4,5]pyrazino[2,1-b][1,3]ox47azepine-10-carboxylic acid
CAS:1616342-45-0
Purity:0.99 Package:500g；1kg
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Products Intro: Product Name:Bictegravir Impurity 19
CAS:1616342-45-0
Purity:95%+ Package:10mg;|30mg;|50mg
Company Name: Jinan Carbotang Biotech Co.,Ltd.
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Products Intro: Product Name:(2R,5S,13aR)-8-methoxy-7,9-dioxo-2,3,4,5,7,9,13,13a-octahydro-2,5-methanopyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazepine-10-carboxylic acid
CAS:1616342-45-0
Purity:98% Package:5KG;1KG
Company Name: Neostar United (Changzhou) Industrial Co., Ltd.
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Products Intro: Product Name:(2R,5S,13aR)-8-Methoxy-7,9-dioxo-2,3,4,5,7,9,13,13a-octahydro-2,5-methanopyrido[1',2':4,5]pyrazino[2
CAS:1616342-45-0
Purity:0.99 Package:1KG;5KG;100KG;1000KG Remarks:1KG,5KG,25KG,200KG
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Products Intro: Product Name:(2R,5S,13aR)-8-methoxy-7,9-dioxo-2,3,4,5,7,9,13,13a-octahydro-2,5-methanopyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazepine-10-carboxylic acid
CAS:1616342-45-0
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(2R,5S,13aR)-8-methoxy-7,9-dioxo-2,3,4,5,7,9,13,13a-octahydro-2,5-methanopyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazepine-10-carboxylic acid manufacturers
(2R,5S,13aR)-8-methoxy-7,9-dioxo-2,3,4,5,7,9,13,13a-octahydro-2,5-methanopyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazepine-10-carboxylic acid Basic information
Product Name:(2R,5S,13aR)-8-methoxy-7,9-dioxo-2,3,4,5,7,9,13,13a-octahydro-2,5-methanopyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazepine-10-carboxylic acid
Synonyms:(2R,5S,13aR)-8-methoxy-7,9-dioxo-2,3,4,5,7,9,13,13a-octahydro-2,5-methanopyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazepine-10-carboxylic acid;(2R,5S)-8-methoxy-7,9-dioxo-2,3,4,5,7,9,13,13a-octahydro-2,5-methanopyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazepine-10-carboxylic acid;(2R,5S,13aR)-8-methoxy-7,9-dioxo-2,3,4,5,7,9,13,13a-octahydro-2,5-methanopyrido[1',2':4,5]pyrazino[2,1-b][1,3]ox47azepine-10-carboxylic acid;BNKY010-BC01;(2R,5S,13aR)-2,3,4,5,7,9,13,13a-Octahydro-8-methoxy-7,9-dioxo-2,5-methanopyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazepine-10-carboxylic acid;(2R,5S,13aR)-8-methoxy-7,9-dioxo-2,3,4,5,7,9,13,13a-octahydro-2,5-methanopyrido[1',2':4,5]pyrazino[2;2,5-Methanopyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazepine-10-carboxylic acid, 2,3,4,5,7,9,13,13a-octahydro-8-methoxy-7,9-dioxo-, (2R,5S,13aR)-;Bictegravir Impurity 12
CAS:1616342-45-0
MF:C15H16N2O6
MW:320.3
EINECS:
Product Categories:
Mol File:1616342-45-0.mol
(2R,5S,13aR)-8-methoxy-7,9-dioxo-2,3,4,5,7,9,13,13a-octahydro-2,5-methanopyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazepine-10-carboxylic acid Structure
(2R,5S,13aR)-8-methoxy-7,9-dioxo-2,3,4,5,7,9,13,13a-octahydro-2,5-methanopyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazepine-10-carboxylic acid Chemical Properties
Boiling point 591.5±50.0 °C(Predicted)
density 1.58±0.1 g/cm3(Predicted)
pka5.52±0.20(Predicted)
InChIInChI=1S/C15H16N2O6/c1-22-13-11-14(19)17-7-2-3-8(4-7)23-10(17)6-16(11)5-9(12(13)18)15(20)21/h5,7-8,10H,2-4,6H2,1H3,(H,20,21)/t7-,8+,10+/m0/s1
InChIKeyGARGTTZRFPGJSI-QXFUBDJGSA-N
SMILESO1[C@@]2([H])C[C@]([H])(CC2)N2C(=O)C3=C(OC)C(=O)C(C(O)=O)=CN3C[C@@]12[H]
Safety Information
MSDS Information
(2R,5S,13aR)-8-methoxy-7,9-dioxo-2,3,4,5,7,9,13,13a-octahydro-2,5-methanopyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazepine-10-carboxylic acid Usage And Synthesis
Uses(2R,5S,13aR)-8-Methoxy-7,9-dioxo-2,3,4,5,7,9,13,13a-octahydro-2,5-methanopyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazepine-10-carboxylic Acid is a Bictegravir (1611493-60-7) intermediate and an antiviral agent.
(2R,5S,13aR)-8-methoxy-7,9-dioxo-2,3,4,5,7,9,13,13a-octahydro-2,5-methanopyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazepine-10-carboxylic acid Preparation Products And Raw materials
Raw materials2,5-Pyridinedicarboxylic acid, 1-(2,2-dihydroxyethyl)-1,4-dihydro-3-methoxy-4-oxo-, 2-methyl ester-->(1R,3S)-3-AMinocyclopentanol hydrochloride-->1-(2,2-diMethoxyethyl)-5-Methoxy-6-(Methoxycarbonyl)-4-oxo-1,4-dihydropyridine-3-carboxylic acid-->(1R,3S)-3-Aminocyclopentanol
Tag:(2R,5S,13aR)-8-methoxy-7,9-dioxo-2,3,4,5,7,9,13,13a-octahydro-2,5-methanopyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazepine-10-carboxylic acid(1616342-45-0) Related Product Information
Salmeterol 1-(4-Acetyloxy)-3-((acetyloxy)methyl)phenyl)-2-bromoethanone 5-(2R)-2-Oxiranyl-8-benzyloxy-2(1H)-quinolinone Bictegravir GSK1349572 2-BROMO-1-[4-HYDROXY-3-(HYDROXYMETHYL)PHENYL]ETHAN-1-ONE O-Methyl Dolutegravir 4-Acetoxy-3-acetoxymethylacetophenone (6a,11b,16a,17a)-6,9-Difluoro-11,17-dihydroxy-16-methyl-3-oxoandrosta-1,4-diene-17-carboxylic acid (4R,12aS)-7-Methoxy-4-Methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-[1,3]oxazino[3,2-d]pyrido[1,2-a]pyrazine-9-carboxylic acid N-(2-Chloropyrimidin-4-YL)-2,3-dimethyl-2H-indazol-6-amine N-(2-chloropyriMidin-4-yl)-N,2,3-triMethyl-2H-indazol-6-aMine (2R,5S,13aR)-8-methoxy-7,9-dioxo-N-(2,4,6-trifluorobenzyl)-2,3,4,5,7,9,13,13a-octahydro-2,5-methanopyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazepine-10-carboxamide 2,4,6-TRIFLUOROBENZYL AMINE 1-(2,2-diMethoxyethyl)-5-Methoxy-6-(Methoxycarbonyl)-4-oxo-1,4-dihydropyridine-3-carboxylic acid BIS(3,5-DIBROMOSALICYL) FUMARATE