GUANOSINE 3':5'-CYCLIC MONOPHOSPHATE manufacturers
- 3',5'-cyclic GMP
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- $1.00
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2020-01-10
- CAS:7665-99-8
- Min. Order: 1KG
- Purity: ≥98%
- Supply Ability: 20 tons
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| | GUANOSINE 3':5'-CYCLIC MONOPHOSPHATE Basic information |
| | GUANOSINE 3':5'-CYCLIC MONOPHOSPHATE Chemical Properties |
| Melting point | >242°C (dec.) | | density | 2+-.0.1 g/cm3(Predicted) | | storage temp. | -20°C | | solubility | 1% sodium bicarbonate: 50 mg/mL | | form | powder | | pka | 1.03±0.60(Predicted) | | color | white | | Stability: | Hygroscopic | | InChI | InChI=1S/C10H12N5O7P/c11-10-13-7-4(8(17)14-10)12-2-15(7)9-5(16)6-3(21-9)1-20-23(18,19)22-6/h2-3,5-6,9,16H,1H2,(H,18,19)(H3,11,13,14,17)/t3-,5-,6-,9-/m1/s1 | | InChIKey | ZOOGRGPOEVQQDX-UUOKFMHZSA-N | | SMILES | O=C1N=C(NC2=C1N=CN2[C@@H]1O[C@]2([H])COP(O[C@@]2([H])[C@H]1O)(O)=O)N |
| Hazard Codes | Xi | | Risk Statements | 36/37/38 | | Safety Statements | 22-26-36 | | WGK Germany | 3 | | HS Code | 29349990 | | Storage Class | 11 - Combustible Solids | | Hazard Classifications | Eye Irrit. 2
Skin Irrit. 2
STOT SE 3 | | Toxicity | The product
formed by the guanylate cyclase enzymes from GTP. It is
a cellular “second messenger,” participating in the regulation
of many intracellular events. Toxicants (e.g., nitroprusside)
may cause physiological changes by interfering with aspects of cyclic GMP metabolism. |
| | GUANOSINE 3':5'-CYCLIC MONOPHOSPHATE Usage And Synthesis |
| Chemical Properties | White powder | | Uses | Guanosine 3'',5''-Cyclic Monophosphate is an intracellular second messenger which are involved in the transduction of a diverse array of stimuli, mediating metabolic and growth regulation. | | Definition | ChEBI: A 3',5'-cyclic purine nucleotide that is 3',5'-cyclic GMP. | | Biochem/physiol Actions | An important second messenger, cGMP is a major intracellular mediator of extracellular signals such as nitric oxide and natriuretic peptides. Cyclic GMP interacts with three types of intracellular receptor proteins: cGMP-dependent protein kinases, cGMP-regulated channels, and cGMP-regulated cyclic nucleotide phosphodiesterases. A primary action of elevated cGMP levels in vivo is the stimulation of cGMP-dependent protein kinase (PKG). |
| | GUANOSINE 3':5'-CYCLIC MONOPHOSPHATE Preparation Products And Raw materials |
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