Bromo-PEG1-azide manufacturers
- N3-PEG1-Br
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2026-07-24
- CAS:1144106-65-9
- Min. Order: 1g
- Purity: 98%
- Supply Ability: 1g/bottle, 10g/bottle, 100g/bottle
- Azido-PEG1-Br
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2025-06-07
- CAS:1144106-65-9
- Min. Order: 1g
- Purity: >98.00%
- Supply Ability: 1g
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| | Bromo-PEG1-azide Basic information |
| Product Name: | Bromo-PEG1-azide | | Synonyms: | Bromo-PEG1-azide;Bromo-PEG1-C2-azide;Bromo-PEG1-azide, Bromo-PEG1-N3;1-Azido-2-(2-bromoethoxy)ethane/Bromo-PEG1-C2-azide;inhibit,PROTAC Linkers,Bromo-PEG-1-C2-azide,BromoPEG1C2azide,Inhibitor,Bromo PEG1 C2 azide;N3-PEG1-CH2CH2Br;N3-PEG1-Br;1-azido-2-(2-bromoethoxy)ethane | | CAS: | 1144106-65-9 | | MF: | C4H8BrN3O | | MW: | 194.03 | | EINECS: | | | Product Categories: | PEG | | Mol File: | 1144106-65-9.mol |  |
| | Bromo-PEG1-azide Chemical Properties |
| storage temp. | Storage temp. 2-8°C | | solubility | Soluble in DMSO, DCM, DMF | | form | Liquid | | color | Colorless to light yellow |
| | Bromo-PEG1-azide Usage And Synthesis |
| Description | Bromo-PEG1-azide is a bifunctional PEG linker with a bromide (Br)group and an azide(N3) group. The azide group can react with alkyne, BCN, DBCO via Click Chemistry to yield a stable triazole linkage. The bromide (Br) is a good leaving group for nucleophilic substitution reactions. | | Uses | Bromo-PEG1-C2-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Bromo-PEG1-C2-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups. | | IC 50 | PEGs | | References | [1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005 |
| | Bromo-PEG1-azide Preparation Products And Raw materials |
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