- 2,4,6-Trimethybromombenzene
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- $100.00 / 1KG
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2025-09-25
- CAS:576-83-0
- Min. Order: 1KG
- Purity: 99%
- Supply Ability: g-kg-tons, free sample is available
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| | 2,4,6-Trimethybromombenzene Basic information |
| Product Name: | 2,4,6-Trimethybromombenzene | | Synonyms: | 2,4,6-trimethybromombenzene;2,4,6-Trimethylphenyl bromide;2,4,6-TRIMETHYLBROMOBENZENE;2-Bromomesifylene;1-bromo-2,4,6-trimethylbenzene;1-Bromomesitylene;Mesitylene, 2-bromo-;TIMTEC-BB SBB007975 | | CAS: | 576-83-0 | | MF: | C9H11Br | | MW: | 199.09 | | EINECS: | 209-405-9 | | Product Categories: | Aromatic Hydrocarbons (substituted) & Derivatives | | Mol File: | 576-83-0.mol |  |
| | 2,4,6-Trimethybromombenzene Chemical Properties |
| Melting point | 2 °C(lit.) | | Boiling point | 225 °C(lit.) | | density | 1.301 g/mL at 25 °C(lit.) | | refractive index | n20/D 1.552(lit.) | | Fp | 205 °F | | storage temp. | Sealed in dry,Room Temperature | | form | Liquid | | color | Clear colorless to very slightly yellow | | Water Solubility | Insoluble in water(20°C) . | | Sensitive | Light Sensitive | | BRN | 1907245 | | InChI | InChI=1S/C9H11Br/c1-6-4-7(2)9(10)8(3)5-6/h4-5H,1-3H3 | | InChIKey | RRTLQRYOJOSPEA-UHFFFAOYSA-N | | SMILES | C1(C)=CC(C)=CC(C)=C1Br | | CAS DataBase Reference | 576-83-0(CAS DataBase Reference) | | NIST Chemistry Reference | Benzene, 2-bromo-1,3,5-trimethyl-(576-83-0) | | EPA Substance Registry System | 2-Bromomesitylene (576-83-0) |
| Hazard Codes | Xi | | Risk Statements | 36/37/38 | | Safety Statements | 26-36-36/37/39-23 | | WGK Germany | 3 | | TSCA | TSCA listed | | HS Code | 29036990 | | Storage Class | 10 - Combustible liquids | | Hazard Classifications | STOT SE 3 |
| | 2,4,6-Trimethybromombenzene Usage And Synthesis |
| Chemical Properties | colorless liquid | | Uses | 2-Bromomesitylene is a useful synthetic intermediate, Aromatics, Boron Derivatives, Catalyst. It is an intermediate used to prepare Hydrogen[4-[bis(2,4,6-trimethylphenyl)phosphino]-2,3,5,6-tetrafluorophenyl]hydrobis(2,3,4,5,6-pentafluorophenyl)borate (H714510) which is a frustrated phosphonium borate for metal-free catalytic hydrogenation of imines. | | Synthesis | The general procedure for the synthesis of 2-bromo-1,3,5-trimethylbenzene from 1,3,5-trimethylbenzene was as follows: N-bromosuccinimide (NBS, 1.0 mmol) and Catalyst 1 (0.1 or 1 mol% Au based on the substrate) were accurately weighed and added to 10 mL of a sealed reaction vessel, followed by 1,2-dichloroethane (DCE, 2 mL) and 1,3,5- trimethylbenzene (1.0 mmol). The reaction mixture was stirred at a set temperature for a specified time. Upon completion of the reaction, the catalyst was removed by separation using a magnet, followed by concentration of the reaction solution under reduced pressure and final purification by column chromatography to afford the target product 2-bromo-1,3,5-trimethylbenzene. | | References | [1] Journal of Organic Chemistry, 1993, vol. 58, # 11, p. 3072 - 3075
[2] Tetrahedron, 2009, vol. 65, # 22, p. 4429 - 4439
[3] Angewandte Chemie - International Edition, 2010, vol. 49, # 11, p. 2028 - 2032
[4] Tetrahedron Letters, 2013, vol. 54, # 9, p. 1063 - 1066
[5] Synthesis, 2002, # 2, p. 169 - 171 |
| | 2,4,6-Trimethybromombenzene Preparation Products And Raw materials |
| Raw materials | Mesitylene-->N-Bromosuccinimide-->1,2-Dichloroethane-->1,3,5-TribroMo-2,4,6-TriMethyl-Benzene-->2,4-DIBROMOMESITYLENE | | Preparation Products | 2-METHOXY-3-PYRIDINECARBOXALDEHYDE-->3-METHOXY-PYRIDINE-2-CARBALDEHYDE-->Boron Standard Metal Solution-->3,4,5-TRIMETHYLBENZOIC ACID-->2,4,6-Trimethylbenzenesulfonic acid-->4-BROMO-3,5-DIMETHYL-BENZOIC ACID METHYL ESTER-->2,4,6-Trimethylbenzophenone-->1,3-BIS(2,4,6-TRIMETHYLPHENYL)-IMIDAZOLIDINIUM-CHLORIDE-->2-Bromo-benzene-1,3,5-tricarboxylic acid |
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