- RO495
-
- $35.00
-
2026-07-27
- CAS:1258296-60-4
- Purity: 99.40%
- Supply Ability: 10g
|
| Product Name: | RO495 | | Synonyms: | RO495;RO495/RO-495;RO495 (TYK Tool 1);CS-2667;Benzamide, N-[2-[(2-amino-6-methyl-4-pyrimidinyl)amino]-4-pyridinyl]-2,6-dichloro-;N-(2-((2-amino-6-methylpyrimidin-4-yl)amino)pyridin-4-yl)-2,6-dichlorobenzamide;RO495 (CS-2667);Janus kinase,Inhibitor,inhibit,RO 495,RO495,JAK,RO-495 | | CAS: | 1258296-60-4 | | MF: | C17H14Cl2N6O | | MW: | 389.24 | | EINECS: | | | Product Categories: | | | Mol File: | 1258296-60-4.mol |  |
| | RO495 Chemical Properties |
| density | 1.517±0.06 g/cm3(Predicted) | | storage temp. | Store at -20°C | | solubility | DMSO: 78 mg/mL (200.39 mM);Ethanol: Insoluble | | pka | 10.48±0.70(Predicted) | | form | Solid | | color | Light yellow to yellow | | Water Solubility | Water: Insoluble |
| | RO495 Usage And Synthesis |
| Uses | RO495 is a potent inhibitor of non-receptor tyrosine-protein kinase 2 (TYK2 kinase)[1]. | | References | [1] Tobie D. Lee, et al. A High-Throughput Screen of a Library of Therapeutics Identifies Cytotoxic Substrates of P-glycoprotein. Molecular Pharmacology November 2019, 96 (5) 629-640. DOI:10.1124/mol.119.115964 |
| | RO495 Preparation Products And Raw materials |
|