- 2-Chloropyrazine
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2026-06-30
- CAS:14508-49-7
- Min. Order: 1KG
- Purity: 98.0%
- Supply Ability: 10000KGS
- 2-Chloropyrazine
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- $10.00
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2026-05-28
- CAS:14508-49-7
- Min. Order: 1KG
- Purity: 99.%
- Supply Ability: 10 ton
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| | 2-Chloropyrazine Basic information |
| | 2-Chloropyrazine Chemical Properties |
| Melting point | 153~154℃ | | Boiling point | 153-154 °C (lit.) | | density | 1.283 g/mL at 25 °C (lit.) | | refractive index | n20/D 1.539(lit.) | | Fp | 136 °F | | storage temp. | Inert atmosphere,Room Temperature | | solubility | Soluble in Methanol | | form | Liquid | | pka | -1.10±0.10(Predicted) | | Specific Gravity | 1.283 | | color | Clear colorless to yellow | | Water Solubility | INSOLUBLE | | BRN | 107019 | | InChI | 1S/C4H3ClN2/c5-4-3-6-1-2-7-4/h1-3H | | InChIKey | GELVZYOEQVJIRR-UHFFFAOYSA-N | | SMILES | Clc1cnccn1 | | LogP | 0.700 | | CAS DataBase Reference | 14508-49-7(CAS DataBase Reference) | | NIST Chemistry Reference | Chloropyrazine(14508-49-7) | | EPA Substance Registry System | Pyrazine, chloro- (14508-49-7) |
| Hazard Codes | Xi | | Risk Statements | 36/37/38 | | Safety Statements | 26-36-37/39 | | RIDADR | UN 1993 3/PG 3 | | WGK Germany | 3 | | Hazard Note | Irritant | | TSCA | TSCA listed | | HazardClass | 3 | | PackingGroup | III | | HS Code | 29339990 | | Storage Class | 3 - Flammable liquids | | Hazard Classifications | Flam. Liq. 3 |
| | 2-Chloropyrazine Usage And Synthesis |
| Chemical Properties | clear colorless to yellowish liquid | | Uses | 2-Chloropyrazine is used in cardiotonic, in biological, drug, flavoring and perfumery industry. | | Application | 2-Chloropyrazine is used as a reagent in the synthesis of hetaryloxy benzoxaborole compounds which have antimalarial activity. 2-Chloropyrazine is also used to prepare 4,5-disubstituted 6-aryloxy-1,3-dihydrobenzo[c][1,2]oxaboroles which are broad-spectrum serine β-lactamase inhibitors. | | Definition | ChEBI: 2-chloropyrazine is a member of pyrazines. | | Purification Methods | Fractionally distil it through a short column packed with glass helices. It has apenetrating, mildly pungent odour with a high vapour pressure at room temperature. [Erickson & Spoerri J Am Chem Soc 68 400 1946, Hetman & O.Donnell J Org Chem 28 1682 1963, Beilstein 23/5 V 366.] |
| | 2-Chloropyrazine Preparation Products And Raw materials |
| Raw materials | Glyoxal | | Preparation Products | N-Boc-5,6,7,8-tetrahydro-3-methoxy-[1,2,4]triazolo[4,3-A]pyrazine ,98%-->Methyl 7-aminothieno[2,3-b]pyrazine-6-carboxylate-->1-(2-Pyrazinyl)-piperazine-->3-Chloropyrazine-2-carbonitrile-->3-(Trifluoromethyl)-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyrazine-->2,3-Dichloropyrazine-->3-(Trifluoromethyl)-1,2,4-triazolo[4,3-a]pyrazine-->Pyrazinecarbonitrile-->2-Isopropylpyrazine-->2-Methyl-3-(methylthio)pyrazine-->2,2'-Bipyrazine-->Iodopyrazine-->Pyrazine-->2-(Methylthio)pyrazine-->2-Methoxypyrazine-->Benzyl-pyrazin-2-yl-amine-->Isopropyl-pyrazin-2-yl-aMine-->1-(Pyrazin-2-yl)-1H-pyrazole-4-carbaldehyde-->2-Methyl-2-pyrazin-2-yl-propionitrile |
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