Z-D-Arg-Gly-Arg-PNA 2 HCl

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Company Name: Hangzhou Zhenhe Huacheng Biopharmaceutical Technology Co., Ltd  Gold
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Z-D-Arg-Gly-Arg-PNA 2 HCl manufacturers

Z-D-Arg-Gly-Arg-PNA 2 HCl Basic information
Product Name:Z-D-Arg-Gly-Arg-PNA 2 HCl
Synonyms:S-2765(FXa substrate);Chromogenix S-2238;benzyl N-[(2R)-5-(diaminomethylideneamino)-1-[[2-[[(2S)-5-(diaminomethylideneamino)-1-(4-nitroanilino)-1-oxopentan-2-yl]amino]-2-oxoethyl]amino]-1-oxopentan-2-yl]carbamate;CHROMOGENIX;S2765 ;S 2765;Z-D-ARG-GLY-ARG-PNA.2HCL;Z-RGR-PNA;Z-D-Arg-Gly-Arg-pNA (hydrochloride);Chromogenic Substrate for Thrombin
CAS:113711-77-6
MF:C28H40ClN11O7
MW:678.15
EINECS:
Product Categories:ADC Linker
Mol File:113711-77-6.mol
Z-D-Arg-Gly-Arg-PNA 2 HCl Structure
Z-D-Arg-Gly-Arg-PNA 2 HCl Chemical Properties
storage temp. Store at -20°C
solubility DMF: 14 mg/ml; DMSO: 14 mg/ml; Ethanol: partially soluble; PBS (pH 7.2): 0.5 mg/ml
form A solid
Sequence{Z-D-Arg}-Gly-Arg-{pNA}
Stability:Hygroscopic
InChIKeyZYHXVFYARSJKCR-STMTUNMVNA-N
SMILESN(C1C=CC(N(=O)=O)=CC=1)C(=O)[C@H](CCCNC(N)=N)NC(=O)CNC(=O)[C@@H](CCCNC(N)=N)NC(=O)OCC1C=CC=CC=1.Cl |&1:12,27,r|
Safety Information
MSDS Information
Z-D-Arg-Gly-Arg-PNA 2 HCl Usage And Synthesis
DescriptionZ-D-Arg-Gly-Arg-pNA is a colorimetric substrate for Factor Xa.1,2 Factor Xa preferentially binds to and cleaves the Arg-Gly-Arg (RGR) peptide sequence to release p-nitroanilide (pNA), which can be quantified by colorimetric detection at 405 nm as a measure of Factor Xa activity.
UsesZ-D-Arg-Gly-Arg-pNA Dihydrochloride is a reagent used in the preparation and testing of tripeptides and intermediates (arginine-containing) as reagent for the determination of serine protease.
References1. Gustavsson, S.I., and Arielly, S. New Peptide Derivatives ,(1989).
2. Joo, H.-S., Park, G.-C., Kim, K.-M., et al. Novel alkaline protease from the polychaeta, Periserrula leucophryna: Purification and characterization Proc. Biochem. 36(8-9),893-900(2001).
Z-D-Arg-Gly-Arg-PNA 2 HCl Preparation Products And Raw materials
Tag:Z-D-Arg-Gly-Arg-PNA 2 HCl(113711-77-6) Related Product Information
L-alpha-Phosphatidylserines, brain, porcine Z-Ile-Glu-Thr-Asp-PNA Z-Gly-Pro-Arg-PNA Z-Gly-Gly-Leu-PNA H-D-Phe-Pip-Arg-pNA acetate CATHEPSIN B SUBSTRATE I, COLORIMETRIC Z-ALA-ALA-LEU-PNA Z-ALA-PRO-PNA Z-ARG-PNA HCL Lysophosphatidylethanolamines, egg PG?(egg?PC) Phosphatidylcholines, egg Phosphatidylinositol (Soy) SodiuM D-Arginine amide dihydrochloride Z-D-ARG-GLY-ARG-PNA 2 HCL L-Arginine p-nitroanilide dihydrochloride GLY-ARG P-NITROANILIDE DIHYDROCHLORIDE AC-ARG-PNA HCL