Z-D-ARG-GLY-ARG-PNA 2 HCL manufacturers
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| | Z-D-ARG-GLY-ARG-PNA 2 HCL Basic information |
| Product Name: | Z-D-ARG-GLY-ARG-PNA 2 HCL | | Synonyms: | Z-D-ARG-GLY-ARG-PNA 2 HCL;Z-D-Arg-Gly-Arg-pNA;S-2765(FXa substrate);Chromogenix S-2238;benzyl N-[(2R)-5-(diaminomethylideneamino)-1-[[2-[[(2S)-5-(diaminomethylideneamino)-1-(4-nitroanilino)-1-oxopentan-2-yl]amino]-2-oxoethyl]amino]-1-oxopentan-2-yl]carbamate;CHROMOGENIX;S2765 ;S 2765;Z-D-ARG-GLY-ARG-PNA.2HCL;Z-RGR-PNA | | CAS: | 113711-77-6 | | MF: | C28H40ClN11O7 | | MW: | 678.15 | | EINECS: | | | Product Categories: | ADC Linker | | Mol File: | 113711-77-6.mol |  |
| | Z-D-ARG-GLY-ARG-PNA 2 HCL Chemical Properties |
| storage temp. | Store at -20°C | | solubility | DMF: 14 mg/ml; DMSO: 14 mg/ml; Ethanol: partially soluble; PBS (pH 7.2): 0.5 mg/ml | | form | A solid | | Sequence | {Z-D-Arg}-Gly-Arg-{pNA} | | Stability: | Hygroscopic | | InChIKey | ZYHXVFYARSJKCR-STMTUNMVNA-N | | SMILES | N(C1C=CC(N(=O)=O)=CC=1)C(=O)[C@H](CCCNC(N)=N)NC(=O)CNC(=O)[C@@H](CCCNC(N)=N)NC(=O)OCC1C=CC=CC=1.Cl |&1:12,27,r| |
| | Z-D-ARG-GLY-ARG-PNA 2 HCL Usage And Synthesis |
| Description | Z-D-Arg-Gly-Arg-pNA is a colorimetric substrate for Factor Xa.1,2 Factor Xa preferentially binds to and cleaves the Arg-Gly-Arg (RGR) peptide sequence to release p-nitroanilide (pNA), which can be quantified by colorimetric detection at 405 nm as a measure of Factor Xa activity. | | Uses | Z-D-Arg-Gly-Arg-pNA Dihydrochloride is a reagent used in the preparation and testing of tripeptides and intermediates (arginine-containing) as reagent for the determination of serine protease. | | References | 1. Gustavsson, S.I., and Arielly, S. New Peptide Derivatives ,(1989).
2. Joo, H.-S., Park, G.-C., Kim, K.-M., et al. Novel alkaline protease from the polychaeta, Periserrula leucophryna: Purification and characterization Proc. Biochem. 36(8-9),893-900(2001). |
| | Z-D-ARG-GLY-ARG-PNA 2 HCL Preparation Products And Raw materials |
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