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| | Azido-PEG8-t-butyl ester Basic information |
| Product Name: | Azido-PEG8-t-butyl ester | | Synonyms: | Azido-PEG8-t-butyl ester;Azido-PEG9-t-butly ester;N3-PEG8-CH2CH2COOtBu;Azido-PEG8-COOtBu;Azido-PEG8-Boc;N3-PEG8-CH2CH2COOtBu,Azido-PEG8-t-butyl ester;N3-?PEG8-?t-?butyl ester;4,7,10,13,16,19,22,25-Octaoxaheptacosanoic acid, 27-azido-, 1,1-dimethylethyl ester | | CAS: | 1623791-99-0 | | MF: | C23H45N3O10 | | MW: | 523.62 | | EINECS: | | | Product Categories: | SiChem;peg | | Mol File: | 1623791-99-0.mol |  |
| | Azido-PEG8-t-butyl ester Chemical Properties |
| storage temp. | Store at Room Tem. | | solubility | Soluble in Water, DMSO, DCM, DMF | | form | Liquid | | color | Light yellow to yellow |
| | Azido-PEG8-t-butyl ester Usage And Synthesis |
| Description | Azido-PEG8-t-butyl ester is a click chemistry compound conpprising an azide group and a t-butyl ester moiety. The hydrophilic PEG spacer increases solubility in aqueous media. The azide group can react with alkyne, BCN, DBCO via Click Chemistry to yield a stable triazole linkage. | | Uses | Azido-PEG8-Boc is a PEG- and Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs[1]. Azido-PEG8-Boc is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups. | | IC 50 | PEGs; Alkyl/ether | | References | [1] Garofalo, Antonio, et al. Efficient synthesis of small-sized phosphonated dendrons: potential organic coatings of iron oxide nanoparticles. New Journal of Chemistry (2014), 38(11), 5226-5239. |
| | Azido-PEG8-t-butyl ester Preparation Products And Raw materials |
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