- Azido-PEG3-alcohol
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- $2.00 / 100kg
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2025-10-13
- CAS:86520-52-7
- Min. Order: 1kg
- Purity: 99%
- Supply Ability: 100kg
- azido-PEG3-OH
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- $0.00 / 10g
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2025-06-07
- CAS:86520-52-7
- Min. Order: 10g
- Purity: >99.00%
- Supply Ability: 10g
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| | 2-[2-(2-AZIDOETHOXY)ETHOXY]ETHANOL Basic information |
| | 2-[2-(2-AZIDOETHOXY)ETHOXY]ETHANOL Chemical Properties |
| Fp | -33℃ | | storage temp. | 2-8°C | | solubility | Chloroform (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly) | | form | Oil | | color | Colourless to Light Yellow | | Appearance | colorless liquid | | BRN | 4418543 | | InChI | InChI=1S/C6H13N3O3/c7-9-8-1-3-11-5-6-12-4-2-10/h10H,1-6H2 | | InChIKey | PMNIHDBMMDOUPD-UHFFFAOYSA-N | | SMILES | C(O)COCCOCCN=[N+]=[N-] |
| Hazard Codes | F,Xi | | Risk Statements | 11-38 | | Safety Statements | 16 | | RIDADR | UN 2398 3 / PGII | | WGK Germany | 3 | | HS Code | 2929900090 | | Storage Class | 3 - Flammable liquids | | Hazard Classifications | Flam. Liq. 2 Skin Irrit. 2 |
| | 2-[2-(2-AZIDOETHOXY)ETHOXY]ETHANOL Usage And Synthesis |
| Description | Azido-PEG3-alcohol is a click chemistry PEG linker containing an azide group and a terminal hydroxyl group. The azide group is reactive with alkyne, BCN, DBCO via Click Chemistry to yield a stable triazole linkage. The hydroxyl group enables further derivatization or replacement with other reactive functional groups. | | Chemical Properties | Yellowish Liquid | | Uses | Azido-PEG3-alcohol is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1]. Azido-PEG3-alcohol is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups. | | reaction suitability | reaction type: click chemistry reagent type: linker | | IC 50 | PEGs | | References | [1] Zhang F, et al. Discovery of a new class of PROTAC BRD4 degraders based on a dihydroquinazolinone derivative and lenalidomide/pomalidomide. Bioorg Med Chem. 2020 Jan 1;28(1):115228. DOI:10.1016/j.bmc.2019.115228 |
| | 2-[2-(2-AZIDOETHOXY)ETHOXY]ETHANOL Preparation Products And Raw materials |
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