2-[2-(2-AZIDOETHOXY)ETHOXY]ETHANOL

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Products Intro: Product Name:2-[2-(2-AZIDOETHOXY)ETHOXY]ETHANOL
CAS:86520-52-7
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2-[2-(2-AZIDOETHOXY)ETHOXY]ETHANOL manufacturers

  • Azido-PEG3-alcohol
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  • 2025-10-13
  • CAS:86520-52-7
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  • Purity: 99%
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  • azido-PEG3-OH
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  • 2025-06-07
  • CAS:86520-52-7
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2-[2-(2-AZIDOETHOXY)ETHOXY]ETHANOL Basic information
Product Name:2-[2-(2-AZIDOETHOXY)ETHOXY]ETHANOL
Synonyms:2-[2-(2-AZIDOETHOXY)ETHOXY]ETHANOL;azido-PEG3-OH;Ethanol, 2-[2-(2-azidoethoxy)ethoxy]-;2-[2-(2-azidoethoxy)ethoxy]ethan-1-ol;1-Azido-8-hydroxy-3,6-dioxaoctane;8-Azido-3,6-dioxaoctanol;2-[2-(2-Azidoethoxy)ethoxy]ethanol solution;8-Azido-3,6-dioxaoctanol solution
CAS:86520-52-7
MF:C6H13N3O3
MW:175.18572
EINECS:
Product Categories:Nitric Oxide Reagents;Cross Linking Reagents;building block;peg
Mol File:Mol File
2-[2-(2-AZIDOETHOXY)ETHOXY]ETHANOL Structure
2-[2-(2-AZIDOETHOXY)ETHOXY]ETHANOL Chemical Properties
Fp -33℃
storage temp. 2-8°C
solubility Chloroform (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly)
form Oil
color Colourless to Light Yellow
Appearancecolorless liquid
BRN 4418543
InChIInChI=1S/C6H13N3O3/c7-9-8-1-3-11-5-6-12-4-2-10/h10H,1-6H2
InChIKeyPMNIHDBMMDOUPD-UHFFFAOYSA-N
SMILESC(O)COCCOCCN=[N+]=[N-]
Safety Information
Hazard Codes F,Xi
Risk Statements 11-38
Safety Statements 16
RIDADR UN 2398 3 / PGII
WGK Germany 3
HS Code 2929900090
Storage Class3 - Flammable liquids
Hazard ClassificationsFlam. Liq. 2
Skin Irrit. 2
MSDS Information
2-[2-(2-AZIDOETHOXY)ETHOXY]ETHANOL Usage And Synthesis
DescriptionAzido-PEG3-alcohol is a click chemistry PEG linker containing an azide group and a terminal hydroxyl group. The azide group is reactive with alkyne, BCN, DBCO via Click Chemistry to yield a stable triazole linkage. The hydroxyl group enables further derivatization or replacement with other reactive functional groups.
Chemical PropertiesYellowish Liquid
UsesAzido-PEG3-alcohol is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1]. Azido-PEG3-alcohol is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
reaction suitabilityreaction type: click chemistry
reagent type: linker
IC 50PEGs
References[1] Zhang F, et al. Discovery of a new class of PROTAC BRD4 degraders based on a dihydroquinazolinone derivative and lenalidomide/pomalidomide. Bioorg Med Chem. 2020 Jan 1;28(1):115228. DOI:10.1016/j.bmc.2019.115228
Tag:2-[2-(2-AZIDOETHOXY)ETHOXY]ETHANOL(86520-52-7) Related Product Information
N3-PEG4-tBu Azido-PEG12-NHS ester Azido-PEG8-NHS ester Azido-PEG2-acid Azide-PEG5-t-butyl ester Azido-PEG2-t-butyl ester Azido-PEG5-NHS ester Azido-dPEG4-acid N3-PEG3-tBu Azido-PEG12-t-butyl ester N3-PEG6-tBu 1-Azido-3,6,9-trioxaundecane-11-ol 1-Azidohexaethylene Glycol 3,6,9,12,15,18,21,24-Octaoxapentacosan-1-amine MPEG8-N3 Azido-PEG6 AMINO-PEG12-T-BUTYL ESTER 1-AMINO-3,6,9-TRIOXAUNDECANYL-11-OL

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