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Nextpeptide Inc |
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+86-0571-81612335 +8613336028439 |
| Email: |
sales@nextpeptide.com |
Tos-PEG7-CH2CO2t-butyl ester manufacturers
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| | Tos-PEG7-CH2CO2t-butyl ester Basic information |
| Product Name: | Tos-PEG7-CH2CO2t-butyl ester | | Synonyms: | Tos-PEG7-CH2CO2t-butyl ester;Tos-PEG7-CH2CO2tBu;Tos-PEG6-CH2COOtBu;Tos-PEG6-CH2-Boc;3,6,9,12,15,18-Hexaoxaeicosanoic acid, 20-[[(4-methylphenyl)sulfonyl]oxy]-, 1,1-dimethylethyl ester;Tos-PEG7-t-butyl acetate;Tos-PEG6-CH2COOtBu/3,6,9,12,15,18-Hexaoxaeicosanoic acid, 20-[[(4-methylphenyl)sulfonyl]oxy]-, 1,1-dimethylethyl ester;tert-Butyl 20-(Tosyloxy)-3,6,9,12,15,18-hexaoxaicosan-1-oate | | CAS: | 1530777-90-2 | | MF: | C25H42O11S | | MW: | 550.66 | | EINECS: | | | Product Categories: | | | Mol File: | 1530777-90-2.mol |  |
| | Tos-PEG7-CH2CO2t-butyl ester Chemical Properties |
| storage temp. | Storage temp. 2-8°C | | form | Viscous Liquid | | color | Colorless to light yellow |
| | Tos-PEG7-CH2CO2t-butyl ester Usage And Synthesis |
| Description | Tos-PEG7-CH2CO2tBu is a PEG linker containing a t-butyl ester and a tosyl group. The hydrophilic PEG spacer increases solubility in aqueous media. The t-butyl protected carboxyl group can be deprotected under acidic conditions. The tosyl group is a very good leaving group for nucleophilic substitution reactions. | | Uses | Tos-PEG6-CH2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. | | IC 50 | PEGs; Alkyl/ether | | References | [1] Snaebjornsson MT, et al. Non-canonical functions of enzymes facilitate cross-talk between cell metabolic and regulatory pathways. Exp Mol Med. 2018 Apr 16;50(4):34. DOI:10.1038/s12276-018-0065-6 |
| | Tos-PEG7-CH2CO2t-butyl ester Preparation Products And Raw materials |
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