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| | 4-Methoxyphenylmagnesium bromide Basic information |
| | 4-Methoxyphenylmagnesium bromide Chemical Properties |
| Boiling point | 65-67 °C | | density | 0.955 g/mL at 25 °C | | Fp | −4 °F | | storage temp. | Flammables + water-Freezer (-20°C)e area | | form | Liquid | | color | Yellow to brown | | Water Solubility | Severe reaction | | Sensitive | Air & Moisture Sensitive | | InChI | 1S/C7H7O.BrH.Mg/c1-8-7-5-3-2-4-6-7;;/h3-6H,1H3;1H;/q;;+1/p-1 | | InChIKey | JKXAZEXIOPFJSC-UHFFFAOYSA-M | | SMILES | COc1ccc([Mg]Br)cc1 |
| Hazard Codes | F,C | | Risk Statements | 11-14-19-22-34-14/15-40-37 | | Safety Statements | 16-26-33-36/37/39-45-6A-43B | | RIDADR | UN 2924 3/PG 2 | | WGK Germany | - | | HazardClass | 4.3 | | PackingGroup | II | | HS Code | 29319090 | | Storage Class | 3 - Flammable liquids | | Hazard Classifications | Acute Tox. 4 Oral
Carc. 2
Eye Dam. 1
Flam. Liq. 2
Skin Corr. 1B
STOT SE 3 |
| | 4-Methoxyphenylmagnesium bromide Usage And Synthesis |
| Chemical Properties | Clear to brown solution when properly stored | | Uses | 4-Methoxyphenylmagnesium bromide is applied in Grignard-reactions as a reagent for the introduction of the 4-methoxyphenyl group. | | reaction suitability | reaction type: Grignard Reaction | | Synthesis | A mixture of Mg (13.49 g, 554.99 mmol) and I2 (50.00 mg, 197.00 mol) in THF (260 mL) was degassed and purged 3 times with N 2 , and then compound 1A (86.50 g, 462.49 mmol in THF (200 mL)) was added to the mixture. The mixture was stirred at 25 C for 1 h under N2 atmosphere. The color of the mixture changed. The crude product compound 4-methoxyphenylmagnesium bromide was used in the next step without further purification (97.74 g, crude). |
| | 4-Methoxyphenylmagnesium bromide Preparation Products And Raw materials |
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