3,5-Dihydroxy-7-methoxy-2-(4-methoxy-phenyl)-chromen-4-one

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3,5-Dihydroxy-7-methoxy-2-(4-methoxy-phenyl)-chromen-4-one manufacturers

3,5-Dihydroxy-7-methoxy-2-(4-methoxy-phenyl)-chromen-4-one Basic information

Product Name:	3,5-Dihydroxy-7-methoxy-2-(4-methoxy-phenyl)-chromen-4-one
Synonyms:	KAEMPFEROL-7,4'-DIMETHYL ETHER;3,5-dihydroxy-7-methoxy-2-(4-methoxyphenyl)-4-benzopyrone;3,5-Dihydroxy-7-methoxy-2-(4-methoxy-phenyl)-;2-(4-Methoxyphenyl)-3,5-dihydroxy-7-methoxy-4H-1-benzopyran-4-one;4'-O,7-O-Dimethylkaempferol;Kaempferol 4',7-dimethyl ether;Einecs 239-513-1;3,5-Dihydroxy-7-Methoxy-2-(4-Methoxyphenyl)-4H-chroMen-4-one
CAS:	15486-33-6
MF:	C17H14O6
MW:	314.29
EINECS:	239-513-1
Product Categories:	Flavanols
Mol File:	15486-33-6.mol

3,5-Dihydroxy-7-methoxy-2-(4-methoxy-phenyl)-chromen-4-one Chemical Properties

Safety Information

MSDS Information

3,5-Dihydroxy-7-methoxy-2-(4-methoxy-phenyl)-chromen-4-one Usage And Synthesis

Uses	Kaempferol-7,4'-dimethyl ether is a PTP1B inhibitor, and also can inhibit the production of NO. Kaempferol-7,4'-dimethyl ether shows the inhibition rate of 46.1% at 100 μM. Kaempferol-7,4'-dimethyl ether inhibits PTP1B activity with IC50 value of 16.92 μM[1][2].
Definition	ChEBI: 7,4'-dimethylkaempferol is a dimethoxyflavone that is kaempferol in which the hydroxy groups at position 4' and 7 have been replaced by methoxy groups. It is a component of bee glue and has been isolated from several plant species including Betula exilis, Zingiber mekongense and Alpinia flabellata. It has a role as an antioxidant and a plant metabolite. It is a dimethoxyflavone, a dihydroxyflavone and a member of flavonols. It is functionally related to a kaempferol. It is a conjugate acid of a 7,4'-O-dimethylkaempferol 3-olate.
References	[1] Teeratad, et al. Inhibition of nitric oxide production by compounds from Boesenbergia longiflora using lipopolysaccharide-stimulated RAW264.7 macrophage cells.[J]. Songklanakarin Journal of Science & Technology, 2013. [2] To D-C, et al. PTP1B Inhibitory Flavonoids From Orthosiphon stamineus Benth. and Their Growth Inhibition on Human Breast Cancer Cells. Natural Product Communications. 2020,15(1).

3,5-Dihydroxy-7-methoxy-2-(4-methoxy-phenyl)-chromen-4-one Preparation Products And Raw materials

Tag:3,5-Dihydroxy-7-methoxy-2-(4-methoxy-phenyl)-chromen-4-one(15486-33-6) Related Product Information

Kaempferol 3-(6-O-glucopyranosylglucoside) Kaempferol-3-O-(2,6-di-O-trans-p-coumaroyl)-beta-D-glucopyranoside KaeMpferol 7-O-rhaMnoside KaeMpferol-4'-O-β-D-glucopyranoside kaempferol-3-O-galactoside 7-[[2-O-(6-deoxy-alpha-L-mannopyranosyl)-beta-D-glucopyranosyl]oxy]-3,5-dihydroxy-2-(4-hydroxyphenyl)-4H-benzopyran-4-one Kaempferol 3-neohesperidoside Kaempferol Kaempferol 3-sophoroside-7-glucoside kaempferol 3-O-sophoroside kaempferol-3-O-glucosyl(1-2)rhamnoside KaeMpferol 3-sophoroside-7-rhaMnoside Kaempferol-3-O-(2"-O-β-D- glucopyl)-β-D–rutinoside 4H-1-Benzopyran-4-one, 3-[[6-deoxy-2-O-[6-O-[(2Z)-3-(4-hydroxyphenyl)-1-oxo-2-propen-1-yl]-β-D-glucopyranosyl]-α-L-mannopyranosyl]oxy]-5,7-dihydroxy-2-(4-hydroxyphenyl)- Kaempferol-7-O-glucoside Kaempferol-3-O-rutinoside Kaempferol-3-glucuronide Kaempferol 3-α-L-arabinopyranoside