| Company Name: |
Alfa Aesar |
| Tel: |
400-6106006 |
| Email: |
saleschina@alfa-asia.com |
- L-Lys.2Hcl
-
-
2026-09-11
- CAS:657-26-1
- Min. Order: 1kg
- Purity: 98%
- Supply Ability: 1T+
|
| | L-Lysine dihydrochloride Basic information |
| | L-Lysine dihydrochloride Chemical Properties |
| Melting point | 200-206 °C(lit.) | | alpha | 14 º (c=2, water 18 ºC) | | refractive index | 15 ° (C=2, H2O) | | storage temp. | Keep in dark place,Inert atmosphere,Room temperature | | solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | | form | Crystalline Powder | | color | White to very light yellow | | Water Solubility | Soluble in water (100 mg/ml). | | Sensitive | Hygroscopic | | Merck | 14,5636 | | BRN | 4539715 | | InChI | InChI=1/C6H14N2O2.2ClH/c7-4-2-1-3-5(8)6(9)10;;/h5H,1-4,7-8H2,(H,9,10);2*1H/t5-;;/s3 | | InChIKey | JBBURJFZIMRPCZ-WHWWGIJDNA-N | | SMILES | [C@@H](N)(C(=O)O)CCCCN.Cl.Cl |&1:0,r| | | CAS DataBase Reference | 657-26-1(CAS DataBase Reference) | | EPA Substance Registry System | Lysine dihydrochloride (657-26-1) | | CAS Number Unlabeled | 657-26-1 |
| Hazard Codes | Xi | | Risk Statements | 36/37/38 | | Safety Statements | 22-24/25-37/39-26 | | WGK Germany | 3 | | F | 3-10 | | TSCA | TSCA listed | | HS Code | 29224190 | | Storage Class | 11 - Combustible Solids |
| | L-Lysine dihydrochloride Usage And Synthesis |
| Chemical Properties | white to very light yellow crystalline powder | | Uses | Synthesis of hyperbranched polylysine using the N-hydroxysuccinimide ester of L-lysine dihydrochloride as AB 2 building block. The histidine and lysine standards were prepared from L-histidine monohydro- chloride and L-lysine dihydrochloride respectively. L-Homocitrulline-The copper complex was prepared from L-lysine dihydrochloride in 80 to 86 per cent yields. | | Biological Activity | L-Lysine is an essential proteinogenic α amino acid used in a wide range of applications including as a supplement in cell culture media; a substrate of enzymes such as L-lysine oxidase (EC 1.4.3.14); a component of poly-lysine polymers; and a substrate for oxidation and glycation mechanism studies. | | Synthesis | L-lysine dihydrochloride is an organic intermediate that can be obtained from Boc-Lys-OH as a feedstock by removing the protective groups. HCl (4 M in dioxane, 2.5 mL, 10.0 mmol, 10.0 equiv) was added to a solution of Boc-Lys-OH (297 mg, 1.00 mmol) in MeOH (10 mL). The reaction mixture was stirred for 24 h at room temperature. The solvent was removed under vacuum. The residue was dried under high vacuum for 4 hours to obtain the product. | | Purification Methods | Crystallise it from MeOH, in the presence of excess HCl, by adding diethyl ether. [Yoneya J Biochem (Tokyo) 38 343 1951, Kearley & Ingersoll J Am Chem Soc 73 5783 1951, Beilstein 4 IV 2717.] |
| | L-Lysine dihydrochloride Preparation Products And Raw materials |
|